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• W2335987620 abstract "espanolLos solventes organicos son muy usados en la produccion de pinturas, y sus efectos toxicos son ampliamente conocidos. El proposito de esta investigacion fue establecer los efectos de la exposicion ocupacional a solventes organicos sobre la salud de trabajadores de una fabrica de pinturas. Se hizo un estudio de corte transversal, comparando trabajadores expuestos y no expuestos a solventes. La poblacion estuvo constituida por 220 personas; la muestra, por 63 trabajadores (28,6%), 34 expuestos (33 hombres, 97%, una mujer, 3%) y 29 no expuestos (10 hombres, 35%, 19 mujeres, 65%). Se realizaron: historia medica ocupacional incluyendo entrevista y examen fisico; cuestionario de salud mental; y analisis toxicologicos (tolueno y xileno en sangre; acido hipurico, acetona, metiletilcetona y metilisobutilcetona en orina). No hubo diferencias estadisticamente significativas entre los grupos, respecto al riesgo de sufrir cefalea, conjuntivitis, ardor ocular, disnea, irritabilidad, vertigo, mareos, ni tendencia a la depresion. Solo para el cansancio hubo un riesgo relativo (RR) dos veces mayor de sufrirlo entre los expuestos con respecto a los no expuestos, siendo esta diferencia estadisticamente significativa, para un intervalo de confianza (IC) de 95%, RR = 2,0 (1,2-3,3, 95% IC). Los trabajadores no presentaron alteraciones al examen fisico ni en los analisis toxicologicos, que se pudieran relacionar con la exposicion a solventes, lo que podria atribuirse a: condiciones adecuadas de exposicion, entrenamiento continuo del personal y conocimiento de los riesgos a los que se exponen. Se concluye en la necesidad de aplicar programas de vigilancia epidemiologica dirigidos a monitorear la exposicion ocupacional a solventes, con enfasis en la deteccion precoz de efectos. EnglishOrganic solvents are highly used in paint production and are well known for their toxic effects. The objective of this study was to determine the effects associated with occupational exposures in painting industry workers. A cross-sectional study was conducted, comparing a group of workers exposed to organic solvents with a non-exposed reference group. The target population consisted of 220 workers, with a sample of 34 exposed (33 male, one female) and 29 non-exposed persons (10 male, 19 female). An occupational medical history (including interview and physical examination), mental health questionnaire and certain toxicological analyses (blood toluene and xylene, and urinary measurements of hippuric acid, acetone, methylethylketone and methylisobutylketone) were obtained from the study participants. No significant differences were found between the two groups with respect to symptoms of headache, conjunctivitis, ocular irritation, dyspnea, irritability, vertigo, dizziness, or tendency towards depression. Exposed workers were twice as likely to present fatigue than non-exposed ones (RR = 2.0, 1.2 to 3.3, 95% confidence limits). There were no abnormalities detected through the physical examination or toxicological analysis. This could be attributed to adequate exposure controls, ongoing worker training and/or to worker awareness of the risks in their workplaces.. There is a need to apply surveillance programs to monitor occupational exposure to solvents, with an emphasis on early detection of effects." @default.
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• W2335987620 date "1998-01-01" @default.
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• W2335987620 title "Exposición ocupacional a solventes orgánicos en una fábrica de pinturas en Venezuela, 1997" @default.
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