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• W2336122902 abstract "To review the current literature on safety, efficacy, and measures of surgeon and patient satisfaction with lidocaine hydrochloride gel as a tool for ocular anesthesia.Pubmed search using keywords lidocaine gel, ophthalmic, and surgery and compiling cross-references. Twenty-six total references were reviewed, including 15 prospective randomized controlled trials (RCTs, total N = 933, average N = 62), 6 nonrandomized prospective studies (total N = 234, average N = 39), 2 animal studies, 1 microbiologic study, and 2 letters to the editor.The RCTs and nonrandomized prospective studies evaluated a number of measures including timing of onset of anesthesia, duration of anesthesia, intraoperative and postoperative pain, need for additional anesthetic applications, intracameral lidocaine levels, and adverse effects. Control groups received topical drops, subconjunctival anesthetic, retrobulbar anesthetic, or sham gel. Lidocaine gel was shown to be at least as effective for pain control as alternative therapies in all studies, with longer duration of action than topical drops. Patient and surgeon satisfaction were high, and adverse effects were rare and comparable to those for anesthetic drop formulations. Surgical settings included cataract, pterygium, trabeculectomy, strabismus, intravitreal injection, vitrectomy, and penetrating keratoplasty.Lidocaine gel is a safe, effective, and potentially underutilized tool for ophthalmic surgery." @default.
• W2336122902 created "2016-06-24" @default.
• W2336122902 creator A5045328356 @default.
• W2336122902 creator A5076119737 @default.
• W2336122902 date "2009-10-01" @default.
• W2336122902 modified "2023-10-03" @default.
• W2336122902 title "Safety, efficacy, and patient acceptability of lidocaine hydrochloride ophthalmic gel as a topical ocular anesthetic for use in ophthalmic procedures" @default.
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• W2336122902 doi "https://doi.org/10.2147/opth.s4935" @default.
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