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- W2336140130 abstract "Extracorporeal carbon dioxide removal (ECCO2R) utilizes the fact that it is simpler to clear the blood of CO2 than to oxygenate it. The entire metabolic production of CO2 can often be removed with relatively low blood flows, and accordingly smaller cannulas and simpler equipment. In ARDS, when oxygenation is also challenged, ECCO2R serves to reduce ventilatory demand, allowing lower tidal volumes, better protecting the lung. In obstructive diseases, since oxygenation is usually only modestly impaired, ECCO2R could help to liberate patients from invasive mechanical ventilation or prevent its need in the first place. In patients with chronic obstructive pulmonary disease (COPD) and status asthmaticus, ECCO2R has been shown to improve gas exchange, reduce the work of breathing, reduce dynamic hyperinflation, and allow reduction in ventilatory support. Although certain risks attend ECCO2R use, it also may have advantages compared with invasive ventilation. Clinical trials are needed to define the role for ECCO2R." @default.
- W2336140130 created "2016-06-24" @default.
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- W2336140130 date "2016-01-01" @default.
- W2336140130 modified "2023-09-27" @default.
- W2336140130 title "ECCO2R in Obstructive Diseases: Evidence, Indications, and Exclusions" @default.
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- W2336140130 doi "https://doi.org/10.1007/978-1-4939-3005-0_4" @default.
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