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- W2336255501 abstract "Abstract Objective To compare the prophylactic effectiveness of dexmedetomidine, meperidine, and ketamine for postoperative shivering. Materials and methods A randomised, controlled, double-blind, clinical trial, including 160 patients (ASA I–II) undergoing surgical procedures under general anaesthesia for longer than 1 h. They were randomly assigned to four groups to receive a single intravenous dose: dexmedetomidine 1 μg/kg (group A, n = 33), meperidine 0.4 mg/kg (group B, n = 38), ketamine 0.5 mg/kg (group C, n = 40), or 0.9% saline solution (group D, n = 45), administered 20 min before the skin suture. To avoid bias, the anaesthetic induction and maintenance technique, as well as postoperative follow-up was standardised. Results For any level of shivering, the greatest incidence was observed in the placebo group (47%) ( P P P Conclusion Meperidine given intravenously in a single dose of 0.4 mg/kg is a useful means for preventing postoperative shivering." @default.
- W2336255501 created "2016-06-24" @default.
- W2336255501 creator A5072593996 @default.
- W2336255501 date "2016-11-01" @default.
- W2336255501 modified "2023-10-01" @default.
- W2336255501 title "Comparison of the effectiveness of dexmedetomidine, meperidine and ketamine in the prevention of postoperative shivering" @default.
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- W2336255501 doi "https://doi.org/10.1016/j.redare.2016.06.002" @default.
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