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- W2336285994 abstract "Degisken immun yetersizlik sendromu, erkeklerde ve kad›nlarda ikinci ve ucuncu on y›l›nda ortaya c›kan immun hastal›klar›n bir sendromudur. Hastalarda serum immunoglobulin seviyeleri dusukken, B hucre say›s› normaldir ya da hafif azalm›st›r. S›kl›kla T hucre defektleri gorulur. Hastalarda kulak, gogus ve sinus enfeksiyon s›kl›g› artm›st›r. Barsak enfeksiyonlardan, ayr›ca Giardia intestinalis buyuk bir sorundur. Barsak kanseri ve lenfoma insidans› artm›s olup, degisik organlarda kazeifiye olmam›s granulomlar gorulebilir. Bu yaz›da, hastanemize kronik diyare ile basvuran ve degisken immun yetersizlik sendromu tan›s›n› alan dort hasta literatur ›s›g›nda sunulmustur. Common variable immunodeficiency is a syndrome of immune disorders that may occur spontaneously, usually in the second or third decade of life, in both males and females. These patients usually have very low serum levels of immunoglobulin classes, with normal or slightly reduced numbers of B cells. T cells are also not fully functional in a proportion of patients. Patients with this disorder are susceptible to frequent bacterial infections, particularly of the chest, ears and sinuses. Infection of the gut, particularly with Giardia lamblia is also a significant problem. There is a high incidence of gut cancer and lymphoma and noncaseating granulomas in multiple organs can also occur. In this report four cases with common variable immunodeficiency who presented with chronic diarrhea are discussed in the light of the relevant literature." @default.
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- W2336285994 date "2002-04-01" @default.
- W2336285994 modified "2023-09-27" @default.
- W2336285994 title "Common variable immunodeficiency syndrome: four cases" @default.
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