FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336303620> ?p ?o ?g. }

• W2336303620 endingPage "117" @default.
• W2336303620 startingPage "111" @default.
• W2336303620 abstract "The rapid recruitment of neutrophils from peripheral blood into infected sites is critical step for inflammatory responses; however, the excessive and improper recruitment can lead to serious tissue damages. Thus, it is a promising strategy to inhibit their excessive recruitment for treating inflammation-related disease. Here, we isolated a polysaccharide (RDPA1) from Rosa davurica, to evaluate its physicochemical property and inhibitory effects on neutrophil migration. RDPA1 was obtained by hot-water extraction, ethanol precipitation, and fractionated by DEAE-cellulose and Sepharose CL-6B columns. RDPA1 significantly inhibited in vitro migration of human neutrophils evaluated by transwell chamber and impacted the migratory behavior observed by time-lapsed microscopy, we found the migrated distance and average velocity of RDPA1-treated cells were greatly reduced. In addition, RDPA1 treatment impaired in vivo neutrophil infiltration in the peritonitis mice. RDPA1 exhibited significant blocking capacity of the interaction between β2 integrins and ICAM-1 evaluated by flow cytometry and in vitro protein binding assay. Together, these results suggest RDPA1 could be considered as a potential candidate for developing a novel anti-inflammatory agent." @default.
• W2336303620 created "2016-06-24" @default.
• W2336303620 creator A5006361582 @default.
• W2336303620 creator A5023564133 @default.
• W2336303620 creator A5023929272 @default.
• W2336303620 creator A5055606904 @default.
• W2336303620 creator A5056932320 @default.
• W2336303620 creator A5060155994 @default.
• W2336303620 creator A5073388349 @default.
• W2336303620 date "2016-08-01" @default.
• W2336303620 modified "2023-10-15" @default.
• W2336303620 title "Characterization of a polysaccharide from Rosa davurica and inhibitory activity against neutrophil migration" @default.
• W2336303620 cites W1968834637 @default.
• W2336303620 cites W1970248850 @default.
• W2336303620 cites W1976077517 @default.
• W2336303620 cites W1996720689 @default.
• W2336303620 cites W2004187431 @default.
• W2336303620 cites W2004638361 @default.
• W2336303620 cites W2006360074 @default.
• W2336303620 cites W2016843247 @default.
• W2336303620 cites W2024898420 @default.
• W2336303620 cites W2026199497 @default.
• W2336303620 cites W2036965973 @default.
• W2336303620 cites W2046126561 @default.
• W2336303620 cites W2051749753 @default.
• W2336303620 cites W2059450992 @default.
• W2336303620 cites W2065047527 @default.
• W2336303620 cites W2069375519 @default.
• W2336303620 cites W2075126360 @default.
• W2336303620 cites W2076001179 @default.
• W2336303620 cites W2079299253 @default.
• W2336303620 cites W2088091625 @default.
• W2336303620 cites W2099968214 @default.
• W2336303620 cites W2105064482 @default.
• W2336303620 cites W2133582510 @default.
• W2336303620 cites W2151514508 @default.
• W2336303620 cites W2161077775 @default.
• W2336303620 cites W2182355171 @default.
• W2336303620 cites W2217330407 @default.
• W2336303620 cites W4293247451 @default.
• W2336303620 cites W4320301113 @default.
• W2336303620 doi "https://doi.org/10.1016/j.ijbiomac.2016.04.062" @default.
• W2336303620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27112979" @default.
• W2336303620 hasPublicationYear "2016" @default.
• W2336303620 type Work @default.
• W2336303620 sameAs 2336303620 @default.
• W2336303620 citedByCount "13" @default.
• W2336303620 countsByYear W23363036202017 @default.
• W2336303620 countsByYear W23363036202019 @default.
• W2336303620 countsByYear W23363036202020 @default.
• W2336303620 countsByYear W23363036202021 @default.
• W2336303620 countsByYear W23363036202022 @default.
• W2336303620 countsByYear W23363036202023 @default.
• W2336303620 crossrefType "journal-article" @default.
• W2336303620 hasAuthorship W2336303620A5006361582 @default.
• W2336303620 hasAuthorship W2336303620A5023564133 @default.
• W2336303620 hasAuthorship W2336303620A5023929272 @default.
• W2336303620 hasAuthorship W2336303620A5055606904 @default.
• W2336303620 hasAuthorship W2336303620A5056932320 @default.
• W2336303620 hasAuthorship W2336303620A5060155994 @default.
• W2336303620 hasAuthorship W2336303620A5073388349 @default.
• W2336303620 hasConcept C100817775 @default.
• W2336303620 hasConcept C121332964 @default.
• W2336303620 hasConcept C126322002 @default.
• W2336303620 hasConcept C150903083 @default.
• W2336303620 hasConcept C153400128 @default.
• W2336303620 hasConcept C170493617 @default.
• W2336303620 hasConcept C185592680 @default.
• W2336303620 hasConcept C202751555 @default.
• W2336303620 hasConcept C203014093 @default.
• W2336303620 hasConcept C207001950 @default.
• W2336303620 hasConcept C26291073 @default.
• W2336303620 hasConcept C2776914184 @default.
• W2336303620 hasConcept C2780199535 @default.
• W2336303620 hasConcept C2781227287 @default.
• W2336303620 hasConcept C54166955 @default.
• W2336303620 hasConcept C553184892 @default.
• W2336303620 hasConcept C55493867 @default.
• W2336303620 hasConcept C71924100 @default.
• W2336303620 hasConcept C86803240 @default.
• W2336303620 hasConcept C97355855 @default.
• W2336303620 hasConcept C98274493 @default.
• W2336303620 hasConceptScore W2336303620C100817775 @default.
• W2336303620 hasConceptScore W2336303620C121332964 @default.
• W2336303620 hasConceptScore W2336303620C126322002 @default.
• W2336303620 hasConceptScore W2336303620C150903083 @default.
• W2336303620 hasConceptScore W2336303620C153400128 @default.
• W2336303620 hasConceptScore W2336303620C170493617 @default.
• W2336303620 hasConceptScore W2336303620C185592680 @default.
• W2336303620 hasConceptScore W2336303620C202751555 @default.
• W2336303620 hasConceptScore W2336303620C203014093 @default.
• W2336303620 hasConceptScore W2336303620C207001950 @default.
• W2336303620 hasConceptScore W2336303620C26291073 @default.
• W2336303620 hasConceptScore W2336303620C2776914184 @default.
• W2336303620 hasConceptScore W2336303620C2780199535 @default.
• W2336303620 hasConceptScore W2336303620C2781227287 @default.
• W2336303620 hasConceptScore W2336303620C54166955 @default.
• W2336303620 hasConceptScore W2336303620C553184892 @default.

• next