FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336403757> ?p ?o ?g. }

• W2336403757 endingPage "901" @default.
• W2336403757 startingPage "900" @default.
• W2336403757 abstract "To the Editor: Frailty refers to systematic vulnerability to poor adjustment (e.g., mortality, hospitalization) to a stressor event (e.g., a fall accident) and prevails in old age.1 In the Oporto Centenarian Study, 36.0% of participants were prefrail, and 60.0% were frail based on the Fried scale.2 In the Hong Kong Centenarian Study, based on a 32-item frailty index, 16% of participants were nonfrail, 59% were prefrail, and 25% were frail.3 Few centenarian studies have explored the relationship between frailty and its health consequences. Because frailty can be screened for and managed using multicomponent interventions,1, 4 a deeper understanding of the overlap between frailty and multidimensional health outcomes may help clinicians and policy-makers appreciate the effect of frailty on the well-being of these exceptional survivors. Frailty, comorbidity, and disability correlate strongly with each other in older people,5 but their interaction with self-rated health (SRH), a robust proxy of physical health and health behaviors, in near-centenarians and centenarians is unknown.6 A cross-sectional data analysis of 121 community-dwelling Chinese near-centenarians and centenarians (mean age 97.7 ± 2.3, range 95,108; 74.2% female) was performed to examine the prevalence of overlap between frailty, comorbidity, disability, and poor SRH. Frailty was defined as scoring more than 2 out of 5 on the FRAIL (F = fatigue; R = resistance (strength of grip); A = ambulation; I = illness; L = loss of weight) scale.5 Disability was defined as having difficulty with one or more instrumental activities of daily living (IADLs: shopping, preparing meals, laundry, public transport, telephoning, managing finances). Comorbidity was defined as a score greater than 0 on the Charlson Comorbidity Index.7 Participants who responded very poor or poor to the single-item question, “How do you rate your current health?” were regarded as having poor SRH. The institutional review board of the University of Hong Kong approved this study. Informed consent was obtained before the study. Based on the FRAIL scale, 20% of participants were regarded as nonfrail (score 0), 56% were prefrail (score 1–2), and 24% were frail (score >2). Figure 1 illustrates the prevalence of overlap of frailty, disability, comorbidity, and poor SRH. Every frail participant had at least one comorbidity, one disability, or poor SRH. Frailty co-occurred with poor SRH in 32.4% of participants (24/74), with disability in 31.4% (22/70), and with comorbidity in 26.0% (19/73); 71.0% of participants had poor SRH, disability, or comorbidity or some combination but were not frail. Of all possible combinations, the most common combination was having all four symptoms (frailty, poor SRH, disability, comorbidity; n = 17, 14.0%). Eleven (9.1%) participants could be regarded as robust because they did not meet any of the four parameters. Thus, frailty was found to overlap significantly with adverse functional (IADL dependency), medical (comorbidity), and subjective (poor SRH) health outcomes. Every frail participant had at least one adverse outcome, although having one of these adverse conditions did not necessarily confer frailty, even in these extremely old adults. Furthermore, 90.9% of participants were nonfrail or prefrail or had one or a combination of comorbidity, disability, or poor SRH, indicating that there is much heterogeneity in frailty status among near-centenarians and centenarians. These findings underscore the importance of frailty screening for these exceptional survivors, because their frailty status may lead healthcare professionals to discover multiple underlying health and psychosocial problems. Interventions such as resistance and aerobic exercises, caloric and protein support, dietary supplementation, and reduction of polypharmacy may slow or even reverse the progression of frailty.1, 4 Programs based on the principles of traditional Chinese medicine, such as qigong and tai chi, have also attained preliminary success in improving disability, mobility, and handgrip strength and reducing falls.8, 9 Multidimensional programs, knitting exercises, dietary supplementation, and psychosocial intervention together may ultimately help promote autonomy and participation in family and social roles, adding life to years.10 This is the first study to report the prevalence of overlap of frailty, comorbidity, disability, and poor SRH in community-dwelling near-centenarians and centenarians. The findings show that frailty status may indicate deficits in multiple dimensions of health in these very old adults. It was also found that a significant proportion of community-dwelling near-centenarians and centenarians were not frail, suggesting that frailty could be avoided, or even reversed, even in the tenth decade of life. Portions of the results of this manuscript were presented at the 21st International Centenarian Consortium, Sardinia, Italy, June 18–20, 2015. Conflict of Interest: All authors declare no conflict of interests. This study was supported by the Seed Funding Program for Basic Research, the matching fund from the Department of Social Work and Social Administration at University of Hong Kong (Project No. 104001032), and AXA. Author Contributions: Lau: data analysis, writing the manuscript. Kwan: expert advice, comments on manuscript. Cheung: principal investigator, commentd on manuscript. Sponsor's Role: The funding bodies had no role in the design, methods, subject recruitment, data collection, analysis, or preparation of the paper." @default.
• W2336403757 created "2016-06-24" @default.
• W2336403757 creator A5010094513 @default.
• W2336403757 creator A5058667475 @default.
• W2336403757 creator A5085319776 @default.
• W2336403757 date "2016-04-01" @default.
• W2336403757 modified "2023-10-14" @default.
• W2336403757 title "Overlap of Frailty, Comorbidity, Disability, and Poor Self-Rated Health in Community-Dwelling Near-Centenarians and Centenarians" @default.
• W2336403757 cites W1967619173 @default.
• W2336403757 cites W2000445173 @default.
• W2336403757 cites W2017537727 @default.
• W2336403757 cites W2028717323 @default.
• W2336403757 cites W2034772834 @default.
• W2336403757 cites W2048248802 @default.
• W2336403757 cites W2081237890 @default.
• W2336403757 cites W2092170177 @default.
• W2336403757 cites W2167879582 @default.
• W2336403757 cites W4251826030 @default.
• W2336403757 doi "https://doi.org/10.1111/jgs.14063" @default.
• W2336403757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27100597" @default.
• W2336403757 hasPublicationYear "2016" @default.
• W2336403757 type Work @default.
• W2336403757 sameAs 2336403757 @default.
• W2336403757 citedByCount "10" @default.
• W2336403757 countsByYear W23364037572017 @default.
• W2336403757 countsByYear W23364037572018 @default.
• W2336403757 countsByYear W23364037572019 @default.
• W2336403757 countsByYear W23364037572021 @default.
• W2336403757 countsByYear W23364037572022 @default.
• W2336403757 crossrefType "journal-article" @default.
• W2336403757 hasAuthorship W2336403757A5010094513 @default.
• W2336403757 hasAuthorship W2336403757A5058667475 @default.
• W2336403757 hasAuthorship W2336403757A5085319776 @default.
• W2336403757 hasBestOaLocation W23364037571 @default.
• W2336403757 hasConcept C118552586 @default.
• W2336403757 hasConcept C2779159551 @default.
• W2336403757 hasConcept C71924100 @default.
• W2336403757 hasConcept C74909509 @default.
• W2336403757 hasConceptScore W2336403757C118552586 @default.
• W2336403757 hasConceptScore W2336403757C2779159551 @default.
• W2336403757 hasConceptScore W2336403757C71924100 @default.
• W2336403757 hasConceptScore W2336403757C74909509 @default.
• W2336403757 hasFunder F4320321048 @default.
• W2336403757 hasFunder F4320322170 @default.
• W2336403757 hasIssue "4" @default.
• W2336403757 hasLocation W23364037571 @default.
• W2336403757 hasLocation W23364037572 @default.
• W2336403757 hasLocation W23364037573 @default.
• W2336403757 hasOpenAccess W2336403757 @default.
• W2336403757 hasPrimaryLocation W23364037571 @default.
• W2336403757 hasRelatedWork W1992990069 @default.
• W2336403757 hasRelatedWork W2033834333 @default.
• W2336403757 hasRelatedWork W2081454999 @default.
• W2336403757 hasRelatedWork W2108679242 @default.
• W2336403757 hasRelatedWork W2336403757 @default.
• W2336403757 hasRelatedWork W2529894631 @default.
• W2336403757 hasRelatedWork W2728221742 @default.
• W2336403757 hasRelatedWork W3084463050 @default.
• W2336403757 hasRelatedWork W3092917813 @default.
• W2336403757 hasRelatedWork W99168133 @default.
• W2336403757 hasVolume "64" @default.
• W2336403757 isParatext "false" @default.
• W2336403757 isRetracted "false" @default.
• W2336403757 magId "2336403757" @default.
• W2336403757 workType "article" @default.