FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336440969> ?p ?o ?g. }

• W2336440969 endingPage "1515" @default.
• W2336440969 startingPage "1507" @default.
• W2336440969 abstract "<h3>Aims</h3> The WHO9s draft HCV elimination targets propose an 80% reduction in incidence and a 65% reduction in HCV-related deaths by 2030. We estimate the treatment scale-up required and cost-effectiveness of reaching these targets among injecting drug use (IDU)-acquired infections using Australian disease estimates. <h3>Methods</h3> A mathematical model of HCV transmission, liver disease progression and treatment among current and former people who inject drugs (PWID). Treatment scale-up and the most efficient allocation to priority groups (PWID or patients with advanced liver disease) were determined; total healthcare and treatment costs, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs) compared with inaction were calculated. <h3>Results</h3> 5662 (95% CI 5202 to 6901) courses per year (30/1000 IDU-acquired infections) were required, prioritised to patients with advanced liver disease, to reach the mortality target. 4725 (3278–8420) courses per year (59/1000 PWID) were required, prioritised to PWID, to reach the incidence target; this also achieved the mortality target, but to avoid clinically unacceptable HCV-related deaths an additional 5564 (1959–6917) treatments per year (30/1000 IDU-acquired infections) were required for 5 years for patients with advanced liver disease. Achieving both targets in this way cost $A4.6 ($A4.2–$A4.9) billion more than inaction, but gained 184 000 (119 000–417 000) QALYs, giving an ICER of $A25 121 ($A11 062–$A39 036) per QALY gained. <h3>Conclusions</h3> Achieving WHO elimination targets with treatment scale-up is likely to be cost-effective, based on Australian HCV burden and demographics. Reducing incidence should be a priority to achieve both WHO elimination goals in the long-term." @default.
• W2336440969 created "2016-06-24" @default.
• W2336440969 creator A5013176250 @default.
• W2336440969 creator A5021448672 @default.
• W2336440969 creator A5023179056 @default.
• W2336440969 creator A5023605193 @default.
• W2336440969 creator A5077160653 @default.
• W2336440969 date "2016-04-12" @default.
• W2336440969 modified "2023-10-14" @default.
• W2336440969 title "Treatment scale-up to achieve global HCV incidence and mortality elimination targets: a cost-effectiveness model" @default.
• W2336440969 cites W1486416052 @default.
• W2336440969 cites W1717835252 @default.
• W2336440969 cites W1895949411 @default.
• W2336440969 cites W1967240016 @default.
• W2336440969 cites W1992436155 @default.
• W2336440969 cites W2000926720 @default.
• W2336440969 cites W2047400589 @default.
• W2336440969 cites W2086887894 @default.
• W2336440969 cites W2089948902 @default.
• W2336440969 cites W2093150448 @default.
• W2336440969 cites W2101368910 @default.
• W2336440969 cites W2104563699 @default.
• W2336440969 cites W2106791445 @default.
• W2336440969 cites W2107629382 @default.
• W2336440969 cites W2115399503 @default.
• W2336440969 cites W2117027295 @default.
• W2336440969 cites W2127291044 @default.
• W2336440969 cites W2168019791 @default.
• W2336440969 cites W2274680380 @default.
• W2336440969 cites W2304421451 @default.
• W2336440969 cites W2334770329 @default.
• W2336440969 cites W2412554464 @default.
• W2336440969 cites W2435552101 @default.
• W2336440969 doi "https://doi.org/10.1136/gutjnl-2016-311504" @default.
• W2336440969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27196586" @default.
• W2336440969 hasPublicationYear "2016" @default.
• W2336440969 type Work @default.
• W2336440969 sameAs 2336440969 @default.
• W2336440969 citedByCount "112" @default.
• W2336440969 countsByYear W23364409692016 @default.
• W2336440969 countsByYear W23364409692017 @default.
• W2336440969 countsByYear W23364409692018 @default.
• W2336440969 countsByYear W23364409692019 @default.
• W2336440969 countsByYear W23364409692020 @default.
• W2336440969 countsByYear W23364409692021 @default.
• W2336440969 countsByYear W23364409692022 @default.
• W2336440969 countsByYear W23364409692023 @default.
• W2336440969 crossrefType "journal-article" @default.
• W2336440969 hasAuthorship W2336440969A5013176250 @default.
• W2336440969 hasAuthorship W2336440969A5021448672 @default.
• W2336440969 hasAuthorship W2336440969A5023179056 @default.
• W2336440969 hasAuthorship W2336440969A5023605193 @default.
• W2336440969 hasAuthorship W2336440969A5077160653 @default.
• W2336440969 hasConcept C112930515 @default.
• W2336440969 hasConcept C120665830 @default.
• W2336440969 hasConcept C121332964 @default.
• W2336440969 hasConcept C126322002 @default.
• W2336440969 hasConcept C177713679 @default.
• W2336440969 hasConcept C194828623 @default.
• W2336440969 hasConcept C2776455275 @default.
• W2336440969 hasConcept C2777075537 @default.
• W2336440969 hasConcept C2779134260 @default.
• W2336440969 hasConcept C3019080777 @default.
• W2336440969 hasConcept C61511704 @default.
• W2336440969 hasConcept C64332521 @default.
• W2336440969 hasConcept C71924100 @default.
• W2336440969 hasConceptScore W2336440969C112930515 @default.
• W2336440969 hasConceptScore W2336440969C120665830 @default.
• W2336440969 hasConceptScore W2336440969C121332964 @default.
• W2336440969 hasConceptScore W2336440969C126322002 @default.
• W2336440969 hasConceptScore W2336440969C177713679 @default.
• W2336440969 hasConceptScore W2336440969C194828623 @default.
• W2336440969 hasConceptScore W2336440969C2776455275 @default.
• W2336440969 hasConceptScore W2336440969C2777075537 @default.
• W2336440969 hasConceptScore W2336440969C2779134260 @default.
• W2336440969 hasConceptScore W2336440969C3019080777 @default.
• W2336440969 hasConceptScore W2336440969C61511704 @default.
• W2336440969 hasConceptScore W2336440969C64332521 @default.
• W2336440969 hasConceptScore W2336440969C71924100 @default.
• W2336440969 hasIssue "8" @default.
• W2336440969 hasLocation W23364409691 @default.
• W2336440969 hasLocation W23364409692 @default.
• W2336440969 hasOpenAccess W2336440969 @default.
• W2336440969 hasPrimaryLocation W23364409691 @default.
• W2336440969 hasRelatedWork W2005049219 @default.
• W2336440969 hasRelatedWork W2010804163 @default.
• W2336440969 hasRelatedWork W2041145027 @default.
• W2336440969 hasRelatedWork W2052313548 @default.
• W2336440969 hasRelatedWork W2066175645 @default.
• W2336440969 hasRelatedWork W2115503673 @default.
• W2336440969 hasRelatedWork W2159627298 @default.
• W2336440969 hasRelatedWork W2187740012 @default.
• W2336440969 hasRelatedWork W4288702852 @default.
• W2336440969 hasRelatedWork W639950516 @default.
• W2336440969 hasVolume "66" @default.
• W2336440969 isParatext "false" @default.
• W2336440969 isRetracted "false" @default.
• W2336440969 magId "2336440969" @default.

• next