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- W2336504538 abstract "Cryptogenic fibrosing alveolitis (CFA) is now recognized as a distinct clinico-pathological entity albeit of unknown aetiology and uncertain pathogenesis. The histological pattern has been well described as an inflammatory and fibrosing process, though with wide variation in the degree of involvement in different parts of the lung and between individual cases. The end-stage disease is a honeycomb lung, with the sub-pleural position of the honeycombing being instantly diagnostic. The use of the term CFA as a diagnosis in biopsies simply showing interstitial fibrosis should be avoided, as this diagnosis labels the patient as having a chronic terminal condition and may result in inappropriate treatment with powerful immunosuppresive drugs. Currently, the diagnosis of CFA requires careful histological assessment of either open or thoracoscopic lung biopsies; it should not be made on specimens obtained by transbronchial biopsy." @default.
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- W2336504538 date "1967-03-01" @default.
- W2336504538 modified "2023-10-18" @default.
- W2336504538 title "Diffuse Interstitial Pulmonary Fibrosis" @default.
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- W2336504538 doi "https://doi.org/10.1016/s0025-7125(16)33067-x" @default.
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