FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336612658> ?p ?o ?g. }

• W2336612658 endingPage "6" @default.
• W2336612658 startingPage "72" @default.
• W2336612658 abstract "To assess the role of genetic variation in determining factor VII (FVII) activity and antigen levels we studied a polymorphism located in the 5' region of the gene (5'F7), an intronic mutation (IVS7), and the 353Arg-Gln polymorphism. All the polymorphisms, which showed strong allelic association, analyzed separately or in combination by the one-way analysis of variance, were associated with significantly different FVII levels. The 5'F7 and 353Arg-Gln polymorphic systems, which have very similar allele frequencies, contributed to a similar extent to the total phenotypic variance, whereas the contribution of the IVS7 polymorphism was lower. Genetic variation at the FVII locus, evaluated on combined genotypes, accounted for up to 40% of the phenotype FVII variance. As also shown by the two-way analysis of variance, the use of two out of three markers is advisable, and since the 5'F7 polymorphism can be screened by a simple immunoassay, it should be preferred for population-based studies. No substantial differences between FVII activity and FVII antigen levels were found, thus suggesting that the variation was due to biosynthesis- or stability-mediated mechanisms. The genetic control of FVII levels described in this study plays an important role in determining plasma FVII level variability, which may influence the hemostatic balance." @default.
• W2336612658 created "2016-06-24" @default.
• W2336612658 creator A5005916484 @default.
• W2336612658 creator A5015812167 @default.
• W2336612658 creator A5029202139 @default.
• W2336612658 creator A5040190403 @default.
• W2336612658 creator A5043376581 @default.
• W2336612658 creator A5057150740 @default.
• W2336612658 creator A5057403590 @default.
• W2336612658 creator A5065749799 @default.
• W2336612658 creator A5069798282 @default.
• W2336612658 creator A5081012832 @default.
• W2336612658 date "1996-01-01" @default.
• W2336612658 modified "2023-10-16" @default.
• W2336612658 title "Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma." @default.
• W2336612658 cites W12830774 @default.
• W2336612658 cites W171150731 @default.
• W2336612658 cites W1973658401 @default.
• W2336612658 cites W2025767551 @default.
• W2336612658 cites W2036363775 @default.
• W2336612658 cites W2053868688 @default.
• W2336612658 cites W2054910698 @default.
• W2336612658 cites W2062429189 @default.
• W2336612658 cites W2084124265 @default.
• W2336612658 cites W2093045218 @default.
• W2336612658 cites W2112357129 @default.
• W2336612658 cites W2131803294 @default.
• W2336612658 cites W2136831146 @default.
• W2336612658 cites W2145649393 @default.
• W2336612658 cites W2149221304 @default.
• W2336612658 cites W2273122967 @default.
• W2336612658 cites W2402350085 @default.
• W2336612658 cites W2410744738 @default.
• W2336612658 cites W2419528618 @default.
• W2336612658 cites W2430367416 @default.
• W2336612658 cites W79382813 @default.
• W2336612658 cites W1596798861 @default.
• W2336612658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8548429" @default.
• W2336612658 hasPublicationYear "1996" @default.
• W2336612658 type Work @default.
• W2336612658 sameAs 2336612658 @default.
• W2336612658 citedByCount "49" @default.
• W2336612658 countsByYear W23366126582012 @default.
• W2336612658 countsByYear W23366126582013 @default.
• W2336612658 countsByYear W23366126582015 @default.
• W2336612658 countsByYear W23366126582016 @default.
• W2336612658 countsByYear W23366126582017 @default.
• W2336612658 countsByYear W23366126582018 @default.
• W2336612658 countsByYear W23366126582019 @default.
• W2336612658 countsByYear W23366126582021 @default.
• W2336612658 crossrefType "journal-article" @default.
• W2336612658 hasAuthorship W2336612658A5005916484 @default.
• W2336612658 hasAuthorship W2336612658A5015812167 @default.
• W2336612658 hasAuthorship W2336612658A5029202139 @default.
• W2336612658 hasAuthorship W2336612658A5040190403 @default.
• W2336612658 hasAuthorship W2336612658A5043376581 @default.
• W2336612658 hasAuthorship W2336612658A5057150740 @default.
• W2336612658 hasAuthorship W2336612658A5057403590 @default.
• W2336612658 hasAuthorship W2336612658A5065749799 @default.
• W2336612658 hasAuthorship W2336612658A5069798282 @default.
• W2336612658 hasAuthorship W2336612658A5081012832 @default.
• W2336612658 hasConcept C104317684 @default.
• W2336612658 hasConcept C126322002 @default.
• W2336612658 hasConcept C127716648 @default.
• W2336612658 hasConcept C135763542 @default.
• W2336612658 hasConcept C149737253 @default.
• W2336612658 hasConcept C180754005 @default.
• W2336612658 hasConcept C2778382381 @default.
• W2336612658 hasConcept C2780930249 @default.
• W2336612658 hasConcept C37463918 @default.
• W2336612658 hasConcept C54355233 @default.
• W2336612658 hasConcept C68873052 @default.
• W2336612658 hasConcept C71924100 @default.
• W2336612658 hasConcept C84597430 @default.
• W2336612658 hasConcept C86803240 @default.
• W2336612658 hasConceptScore W2336612658C104317684 @default.
• W2336612658 hasConceptScore W2336612658C126322002 @default.
• W2336612658 hasConceptScore W2336612658C127716648 @default.
• W2336612658 hasConceptScore W2336612658C135763542 @default.
• W2336612658 hasConceptScore W2336612658C149737253 @default.
• W2336612658 hasConceptScore W2336612658C180754005 @default.
• W2336612658 hasConceptScore W2336612658C2778382381 @default.
• W2336612658 hasConceptScore W2336612658C2780930249 @default.
• W2336612658 hasConceptScore W2336612658C37463918 @default.
• W2336612658 hasConceptScore W2336612658C54355233 @default.
• W2336612658 hasConceptScore W2336612658C68873052 @default.
• W2336612658 hasConceptScore W2336612658C71924100 @default.
• W2336612658 hasConceptScore W2336612658C84597430 @default.
• W2336612658 hasConceptScore W2336612658C86803240 @default.
• W2336612658 hasIssue "1" @default.
• W2336612658 hasLocation W23366126581 @default.
• W2336612658 hasOpenAccess W2336612658 @default.
• W2336612658 hasPrimaryLocation W23366126581 @default.
• W2336612658 hasRelatedWork W1975252266 @default.
• W2336612658 hasRelatedWork W2012806395 @default.
• W2336612658 hasRelatedWork W2016312727 @default.
• W2336612658 hasRelatedWork W2045710264 @default.
• W2336612658 hasRelatedWork W2045775869 @default.

• next