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• W2336635409 abstract "Back to table of contents Previous article Next article No AccessRBC and plasma levels of haloperidol and clinical response in schizophreniaPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.139.8.1054AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractThe authors conducted a fixed-dose study of haloperidol blood levels and clinical response in schizophrenic in patients and found that those with steady-state RBC haloperidol levels in the range of 2.4--5.4 ng/ml showed greater improvement than those with lower or higher levels. They found a similar , although nonsignificant, curvilinear relationship between plasma haloperidol levels and clinical response. These findings suggest that the relationship between haloperidol blood levels and clinical response fits a therapeutic window for the treatment of schizophrenia. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byAge-related alteration of haloperidol-serum protein binding18 February 2010 | Journal of Pharmacy and Pharmacology, Vol. 55, No. 1Journal of Clinical Pharmacy and Therapeutics, Vol. 21, No. 4Fundamental & Clinical Pharmacology, Vol. 9, No. 5Haloperidol Concentrations in Patients With Alzheimer's DementiaThe American Journal of Geriatric Psychiatry, Vol. 2, No. 2Neuropsychological test scores and clinical response to neuroleptic drugs in schizophrenic patientsComprehensive Psychiatry, Vol. 33, No. 2Hyperactivity of Associations in Psychosis26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 23, No. 2Biological Psychiatry, Vol. 26, No. 4Neuroleptic Plasma Concentrations and Clinical Response: In Search of a Therapeutic Window30 August 2016 | Drug Intelligence & Clinical Pharmacy, Vol. 22, No. 5Serum haloperidol levels and clinical response in chronic, treatment-resistant schizophrenic patients2 July 2016 | Journal of Psychopharmacology, Vol. 2, No. 2Pharmacology & Therapeutics, Vol. 38, No. 1Journal of Forensic Sciences, Vol. 33, No. 3Clinics in Laboratory Medicine, Vol. 7, No. 2Neuroleptic Blood Levels and Clinical Response1 May 1986 | The Canadian Journal of Psychiatry, Vol. 31, No. 4British Journal of Psychiatry, Vol. 148, No. 2Psychiatry Research, Vol. 14, No. 3Psychiatry Research, Vol. 12, No. 4Psychiatry Research, Vol. 11, No. 3Psychiatry Research, Vol. 11, No. 1Psychiatric Clinics of North America, Vol. 7, No. 3Psychological Medicine, Vol. 14, No. 4Psychiatry and Clinical Neurosciences, Vol. 38, No. 2Nordisk Psykiatrisk Tidsskrift, Vol. 38, No. 1-2 Volume 139Issue 8 August 1982Pages 1054-1056 Metrics PDF download History Published online 1 April 2006 Published in print 1 August 1982" @default.
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