Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336648889> ?p ?o ?g. }
- W2336648889 abstract "Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis that is characterized clinically by frequent presentation with obstructive jaundice, histologically by a dense lymphoplasmacytic infiltrate with fibrosis, and therapeutically by a dramatic response to corticosteroid therapy. Two distinct diseases, type 1 and type 2 AIP, share these features. However, these 2 diseases have unique pancreatic histopathologic patterns and differ significantly in their demographic profiles, clinical presentation, and natural history. Recognizing the popular and long-standing association of the term “AIP” with what is now called “type 1 AIP,” we suggest using “AIP” solely for type 1 AIP and to acknowledge its own distinct disease status by using “idiopathic duct-centric chronic pancreatitis” (IDCP) for type 2 AIP. AIP is the pancreatic manifestation of immunoglobulin G4–related disease (IgG4-RD). The etiopathogenesis of AIP and IgG4-RD is largely unknown. However, the remarkable effectiveness of B-cell depletion therapy with rituximab in patients with AIP and IgG4-RD highlights the crucial role of B cells in its pathogenesis. IDCP is less commonly recognized, and little is known about its pathogenesis. IDCP has no biomarker but is associated with inflammatory bowel disease in w25% of patients. Recently, the international consensus diagnostic criteria for AIP identified combinations of features that are diagnostic of both diseases. Both AIP and IDCP are corticosteroid responsive; however, relapses are common in AIP and rare in IDCP. Therefore, maintenance therapy with either an immunomodulator (eg, azathioprine, 6-mercaptopurine, or mycophenolate mofetil) or rituximab is often necessary for patients with AIP. Long-term survival is excellent for both patients with AIP and patients with IDCP." @default.
- W2336648889 created "2016-06-24" @default.
- W2336648889 creator A5012767113 @default.
- W2336648889 creator A5048460582 @default.
- W2336648889 creator A5080215605 @default.
- W2336648889 date "2015-01-01" @default.
- W2336648889 modified "2023-09-22" @default.
- W2336648889 title "REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY AND HEPATOLOGY" @default.
- W2336648889 cites W1507977629 @default.
- W2336648889 cites W1551766892 @default.
- W2336648889 cites W1615320989 @default.
- W2336648889 cites W1641557591 @default.
- W2336648889 cites W1685267289 @default.
- W2336648889 cites W1898864790 @default.
- W2336648889 cites W1939145404 @default.
- W2336648889 cites W1963556772 @default.
- W2336648889 cites W1966137959 @default.
- W2336648889 cites W1966350082 @default.
- W2336648889 cites W1969615927 @default.
- W2336648889 cites W1970338349 @default.
- W2336648889 cites W1971271788 @default.
- W2336648889 cites W1980033719 @default.
- W2336648889 cites W1982216466 @default.
- W2336648889 cites W1984200136 @default.
- W2336648889 cites W1986864699 @default.
- W2336648889 cites W1988026983 @default.
- W2336648889 cites W1988353585 @default.
- W2336648889 cites W1992949106 @default.
- W2336648889 cites W1993216906 @default.
- W2336648889 cites W1994675456 @default.
- W2336648889 cites W1995220040 @default.
- W2336648889 cites W1995250834 @default.
- W2336648889 cites W1997312920 @default.
- W2336648889 cites W1997445453 @default.
- W2336648889 cites W2000690365 @default.
- W2336648889 cites W2002537558 @default.
- W2336648889 cites W2004252050 @default.
- W2336648889 cites W2006108813 @default.
- W2336648889 cites W2006153978 @default.
- W2336648889 cites W2008022161 @default.
- W2336648889 cites W2008589195 @default.
- W2336648889 cites W2011017433 @default.
- W2336648889 cites W2016726826 @default.
- W2336648889 cites W2019122570 @default.
- W2336648889 cites W2019256148 @default.
- W2336648889 cites W2019858056 @default.
- W2336648889 cites W2020695318 @default.
- W2336648889 cites W2023849333 @default.
- W2336648889 cites W2024455516 @default.
- W2336648889 cites W2025302382 @default.
- W2336648889 cites W2026199677 @default.
- W2336648889 cites W2027639860 @default.
- W2336648889 cites W2027654396 @default.
- W2336648889 cites W2028420844 @default.
- W2336648889 cites W2028751606 @default.
- W2336648889 cites W2030312935 @default.
- W2336648889 cites W2030487909 @default.
- W2336648889 cites W2031477993 @default.
- W2336648889 cites W2031679296 @default.
- W2336648889 cites W2035273687 @default.
- W2336648889 cites W2036555354 @default.
- W2336648889 cites W2036937564 @default.
- W2336648889 cites W2038335265 @default.
- W2336648889 cites W2039130348 @default.
- W2336648889 cites W2041129207 @default.
- W2336648889 cites W2042567949 @default.
- W2336648889 cites W2042657838 @default.
- W2336648889 cites W2047750405 @default.
- W2336648889 cites W2050753305 @default.
- W2336648889 cites W2054000176 @default.
- W2336648889 cites W2055704736 @default.
- W2336648889 cites W2056586537 @default.
- W2336648889 cites W2056930998 @default.
- W2336648889 cites W2060024551 @default.
- W2336648889 cites W2061456247 @default.
- W2336648889 cites W2069863449 @default.
- W2336648889 cites W2071958740 @default.
- W2336648889 cites W2073601476 @default.
- W2336648889 cites W2075587347 @default.
- W2336648889 cites W2082621274 @default.
- W2336648889 cites W2082783569 @default.
- W2336648889 cites W2083422149 @default.
- W2336648889 cites W2084130908 @default.
- W2336648889 cites W2084491229 @default.
- W2336648889 cites W2086053238 @default.
- W2336648889 cites W2087416289 @default.
- W2336648889 cites W2088201219 @default.
- W2336648889 cites W2088328410 @default.
- W2336648889 cites W2090382977 @default.
- W2336648889 cites W2090542053 @default.
- W2336648889 cites W2092221697 @default.
- W2336648889 cites W2097092798 @default.
- W2336648889 cites W2100918713 @default.
- W2336648889 cites W2101939433 @default.
- W2336648889 cites W2110084003 @default.
- W2336648889 cites W2110343119 @default.
- W2336648889 cites W2110662561 @default.
- W2336648889 cites W2111115131 @default.
- W2336648889 cites W2112039471 @default.
- W2336648889 cites W2126983369 @default.