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- W2336707617 abstract "Lymphangiomatosis (eg, generalized lymphatic anomaly) is an abnormal proliferation of lymphatic endothelial cells. It is often a childhood disease, but it may present in adulthood by infiltrating organs and cause obstruction, bleeding, or disruption of lymphatic flow. Pulmonary involvement may be mild or cause diffuse interstitial lung disease, airway obstruction, hemoptysis, chylothorax, chylopericardium, and culminate in respiratory failure. Treatment has been limited to surgical resection or drainage procedures because there is no accepted effective systemic therapy. This report presents a patient with lymphangiomatosis and life-threatening hemoptysis in whom positive immunostaining for c-KIT suggested upregulation of tyrosine kinase and whose disease was controlled with imatinib." @default.
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- W2336707617 date "2016-04-01" @default.
- W2336707617 modified "2023-09-26" @default.
- W2336707617 title "Imatinib Treatment of Lymphangiomatosis (Generalized Lymphatic Anomaly)" @default.
- W2336707617 doi "https://doi.org/10.6004/jnccn.2016.0045" @default.
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