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• W2336749345 abstract "During post-transcriptional gene regulation (PTGR), RNA binding proteins (RBPs) interact with all classes of RNA to control RNA maturation, stability, transport, and translation. Here, we describe Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP), a transcriptome-scale method for identifying RBP binding sites on target RNAs with nucleotide-level resolution. This method is readily applicable to any protein directly contacting RNA, including RBPs that are predicted to bind in a sequence- or structure-dependent manner at discrete RNA recognition elements (RREs), and those that are thought to bind transiently, such as RNA polymerases or helicases." @default.
• W2336749345 created "2016-06-24" @default.
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• W2336749345 date "2016-01-01" @default.
• W2336749345 modified "2023-09-29" @default.
• W2336749345 title "PAR-CLIP: A Method for Transcriptome-Wide Identification of RNA Binding Protein Interaction Sites" @default.
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• W2336749345 doi "https://doi.org/10.1007/978-1-4939-3067-8_10" @default.
• W2336749345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5142217" @default.
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