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- W2336762960 abstract "SEVERAL authors have reported that pineal extracts cause clinical improvement in schizophrenia.1 Altschule2 corroborated these findings and concluded that Protein-free extracts made at a pH of about 8.5 and at temperatures between 55 and 70°C. reverse biochemical abnormalities of schizophrenia and cause clinical improvement. He further stated3 that patients hospitalized for fifteen years or more showed only slight to moderate improvement.On the basis of this earlier work indicating that pineal extracts might be useful in schizophrenia a double-blind study was established to compare the effects of pineal extract¶ with a placebo when given to 8 women with chronic schizophrenia . . ." @default.
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- W2336762960 date "1960-12-29" @default.
- W2336762960 modified "2023-10-18" @default.
- W2336762960 title "A Pilot Study Comparing the Effects of Pineal Extract and a Placebo in Patients with Chronic Schizophrenia" @default.
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- W2336762960 doi "https://doi.org/10.1056/nejm196012292632602" @default.
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