FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2336833511> ?p ?o ?g. }

• W2336833511 endingPage "E300" @default.
• W2336833511 startingPage "E292" @default.
• W2336833511 abstract "The activation state of branched-chain alpha-keto acid dehydrogenase (BCDH) was studied in rat hindlimb muscles during starvation and insulinopenic diabetes, conditions in which circulating branched-chain amino acids (BCAA) are increased and their oxidation is accelerated. Muscle BCDH is predominantly inactive (phosphorylated) in postabsorptive rats but is activated by increased circulating leucine. Diabetes (streptozotocin-induced and spontaneous BB/W) increased circulating BCAA four- to fivefold and BCDH activity approximately threefold. Insulin treatment caused near normalization of circulating BCAA without correcting BCDH activity. Adrenalectomy of diabetics decreased (without normalizing) circulating BCAA and BCDH activation. Starvation caused mild, progressive increases in circulating BCAA and significant activation of BCDH only after 4 days. Leucine infusion activated BCDH in muscle but the activation by leucine was markedly blunted by diabetes. In isolated perfused hindlimbs (control and diabetic) insulin did not affect BCDH significantly; perfusion with leucine activated BCDH, and this response appeared blunted in diabetics. Activation of muscle BCDH may contribute to increased BCAA catabolism in diabetes; the blunted activation response to hyperleucinemia may spare BCAA and contribute to their persistent elevation in plasma." @default.
• W2336833511 created "2016-06-24" @default.
• W2336833511 creator A5011760383 @default.
• W2336833511 creator A5036711707 @default.
• W2336833511 creator A5059712516 @default.
• W2336833511 date "1988-03-01" @default.
• W2336833511 modified "2023-10-13" @default.
• W2336833511 title "Effects of diabetes and starvation on skeletal muscle branched-chain alpha-keto acid dehydrogenase activity" @default.
• W2336833511 cites W1548643016 @default.
• W2336833511 cites W1592077310 @default.
• W2336833511 cites W1593344292 @default.
• W2336833511 cites W1600370018 @default.
• W2336833511 cites W1765190831 @default.
• W2336833511 cites W1982115462 @default.
• W2336833511 cites W1985482597 @default.
• W2336833511 cites W1997404599 @default.
• W2336833511 cites W2025421578 @default.
• W2336833511 cites W2026370296 @default.
• W2336833511 cites W2049663562 @default.
• W2336833511 cites W2056197982 @default.
• W2336833511 cites W2069161027 @default.
• W2336833511 cites W2084862063 @default.
• W2336833511 cites W2088055031 @default.
• W2336833511 cites W2094769502 @default.
• W2336833511 cites W2124134528 @default.
• W2336833511 cites W2325903650 @default.
• W2336833511 cites W2344526997 @default.
• W2336833511 cites W2415104947 @default.
• W2336833511 cites W43280368 @default.
• W2336833511 cites W2170562590 @default.
• W2336833511 doi "https://doi.org/10.1152/ajpendo.1988.254.3.e292" @default.
• W2336833511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2964788" @default.
• W2336833511 hasPublicationYear "1988" @default.
• W2336833511 type Work @default.
• W2336833511 sameAs 2336833511 @default.
• W2336833511 citedByCount "25" @default.
• W2336833511 countsByYear W23368335112013 @default.
• W2336833511 countsByYear W23368335112016 @default.
• W2336833511 countsByYear W23368335112018 @default.
• W2336833511 countsByYear W23368335112020 @default.
• W2336833511 countsByYear W23368335112021 @default.
• W2336833511 countsByYear W23368335112022 @default.
• W2336833511 countsByYear W23368335112023 @default.
• W2336833511 crossrefType "journal-article" @default.
• W2336833511 hasAuthorship W2336833511A5011760383 @default.
• W2336833511 hasAuthorship W2336833511A5036711707 @default.
• W2336833511 hasAuthorship W2336833511A5059712516 @default.
• W2336833511 hasConcept C126322002 @default.
• W2336833511 hasConcept C134018914 @default.
• W2336833511 hasConcept C185592680 @default.
• W2336833511 hasConcept C197683979 @default.
• W2336833511 hasConcept C2776580952 @default.
• W2336833511 hasConcept C2779306644 @default.
• W2336833511 hasConcept C2779959927 @default.
• W2336833511 hasConcept C2780606744 @default.
• W2336833511 hasConcept C2780677274 @default.
• W2336833511 hasConcept C515207424 @default.
• W2336833511 hasConcept C55493867 @default.
• W2336833511 hasConcept C555293320 @default.
• W2336833511 hasConcept C62231903 @default.
• W2336833511 hasConcept C71924100 @default.
• W2336833511 hasConcept C86803240 @default.
• W2336833511 hasConcept C96942376 @default.
• W2336833511 hasConceptScore W2336833511C126322002 @default.
• W2336833511 hasConceptScore W2336833511C134018914 @default.
• W2336833511 hasConceptScore W2336833511C185592680 @default.
• W2336833511 hasConceptScore W2336833511C197683979 @default.
• W2336833511 hasConceptScore W2336833511C2776580952 @default.
• W2336833511 hasConceptScore W2336833511C2779306644 @default.
• W2336833511 hasConceptScore W2336833511C2779959927 @default.
• W2336833511 hasConceptScore W2336833511C2780606744 @default.
• W2336833511 hasConceptScore W2336833511C2780677274 @default.
• W2336833511 hasConceptScore W2336833511C515207424 @default.
• W2336833511 hasConceptScore W2336833511C55493867 @default.
• W2336833511 hasConceptScore W2336833511C555293320 @default.
• W2336833511 hasConceptScore W2336833511C62231903 @default.
• W2336833511 hasConceptScore W2336833511C71924100 @default.
• W2336833511 hasConceptScore W2336833511C86803240 @default.
• W2336833511 hasConceptScore W2336833511C96942376 @default.
• W2336833511 hasIssue "3" @default.
• W2336833511 hasLocation W23368335111 @default.
• W2336833511 hasLocation W23368335112 @default.
• W2336833511 hasOpenAccess W2336833511 @default.
• W2336833511 hasPrimaryLocation W23368335111 @default.
• W2336833511 hasRelatedWork W156420595 @default.
• W2336833511 hasRelatedWork W1967884851 @default.
• W2336833511 hasRelatedWork W1989577895 @default.
• W2336833511 hasRelatedWork W2004055858 @default.
• W2336833511 hasRelatedWork W2031623187 @default.
• W2336833511 hasRelatedWork W2032110122 @default.
• W2336833511 hasRelatedWork W2084957500 @default.
• W2336833511 hasRelatedWork W2119527577 @default.
• W2336833511 hasRelatedWork W2338220152 @default.
• W2336833511 hasRelatedWork W50364286 @default.
• W2336833511 hasVolume "254" @default.
• W2336833511 isParatext "false" @default.
• W2336833511 isRetracted "false" @default.
• W2336833511 magId "2336833511" @default.

• next