Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337011191> ?p ?o ?g. }
- W2337011191 endingPage "477" @default.
- W2337011191 startingPage "471" @default.
- W2337011191 abstract "Triethyltin binds to native cat and rat haemoglobin but not to their denatured forms or to other animal haemoglobins. Two molecules of the organotin bind to one molecule of R-state cat haemoglobin with affinity constants of about 1 × 105 M-1. Little or no triethyltin is bound to the deoxygenated (T-state) protein. Binding appears to be dependent upon the existence of a specific three-dimensional configuration of cysteine and histidine residues. The properties of the triethyltin-cat haemoglobin complex are consistent with those of a haemoglobin conformer whose allosteric equilibrium is displaced toward the R-state. Its oxygen affinity and rate of oxidation by nitrite is increased, and the rate of reduction of the methaemoglobin derivative by ascorbate is decreased. These effects of triethyltin are opposite and antagonistic to the effects of inositol hexaphosphate. They are exerted on the alpha- as well as beta-haem groups, even though triethyltin is bound at sites on alpha-globin far removed from the haem groups." @default.
- W2337011191 created "2016-06-24" @default.
- W2337011191 creator A5049509494 @default.
- W2337011191 creator A5064640760 @default.
- W2337011191 date "1986-01-15" @default.
- W2337011191 modified "2023-09-29" @default.
- W2337011191 title "Organotin-protein interactions. Binding of triethyltin bromide to cat haemoglobin" @default.
- W2337011191 cites W138422244 @default.
- W2337011191 cites W1516957708 @default.
- W2337011191 cites W1622853955 @default.
- W2337011191 cites W1775372295 @default.
- W2337011191 cites W1777721252 @default.
- W2337011191 cites W1910226981 @default.
- W2337011191 cites W1967104325 @default.
- W2337011191 cites W1969136884 @default.
- W2337011191 cites W1971151780 @default.
- W2337011191 cites W1981644133 @default.
- W2337011191 cites W198681247 @default.
- W2337011191 cites W1987891858 @default.
- W2337011191 cites W1993068721 @default.
- W2337011191 cites W1995680430 @default.
- W2337011191 cites W1997423266 @default.
- W2337011191 cites W1999411315 @default.
- W2337011191 cites W2004194157 @default.
- W2337011191 cites W2012242419 @default.
- W2337011191 cites W2026911129 @default.
- W2337011191 cites W2030447670 @default.
- W2337011191 cites W2038179420 @default.
- W2337011191 cites W2044744685 @default.
- W2337011191 cites W2047401261 @default.
- W2337011191 cites W2080012882 @default.
- W2337011191 cites W2086859369 @default.
- W2337011191 cites W2091365251 @default.
- W2337011191 cites W2120135466 @default.
- W2337011191 cites W2125087906 @default.
- W2337011191 cites W2157418135 @default.
- W2337011191 cites W2322315864 @default.
- W2337011191 cites W2337615768 @default.
- W2337011191 doi "https://doi.org/10.1042/bj2330471" @default.
- W2337011191 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1153049" @default.
- W2337011191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3954745" @default.
- W2337011191 hasPublicationYear "1986" @default.
- W2337011191 type Work @default.
- W2337011191 sameAs 2337011191 @default.
- W2337011191 citedByCount "30" @default.
- W2337011191 countsByYear W23370111912012 @default.
- W2337011191 countsByYear W23370111912014 @default.
- W2337011191 countsByYear W23370111912020 @default.
- W2337011191 crossrefType "journal-article" @default.
- W2337011191 hasAuthorship W2337011191A5049509494 @default.
- W2337011191 hasAuthorship W2337011191A5064640760 @default.
- W2337011191 hasBestOaLocation W23370111912 @default.
- W2337011191 hasConcept C125996951 @default.
- W2337011191 hasConcept C127503593 @default.
- W2337011191 hasConcept C166342909 @default.
- W2337011191 hasConcept C178790620 @default.
- W2337011191 hasConcept C181199279 @default.
- W2337011191 hasConcept C185592680 @default.
- W2337011191 hasConcept C26865036 @default.
- W2337011191 hasConcept C2776217839 @default.
- W2337011191 hasConcept C2776300020 @default.
- W2337011191 hasConcept C2778460671 @default.
- W2337011191 hasConcept C2778917026 @default.
- W2337011191 hasConcept C32909587 @default.
- W2337011191 hasConcept C540031477 @default.
- W2337011191 hasConcept C55493867 @default.
- W2337011191 hasConcept C71240020 @default.
- W2337011191 hasConcept C77562769 @default.
- W2337011191 hasConceptScore W2337011191C125996951 @default.
- W2337011191 hasConceptScore W2337011191C127503593 @default.
- W2337011191 hasConceptScore W2337011191C166342909 @default.
- W2337011191 hasConceptScore W2337011191C178790620 @default.
- W2337011191 hasConceptScore W2337011191C181199279 @default.
- W2337011191 hasConceptScore W2337011191C185592680 @default.
- W2337011191 hasConceptScore W2337011191C26865036 @default.
- W2337011191 hasConceptScore W2337011191C2776217839 @default.
- W2337011191 hasConceptScore W2337011191C2776300020 @default.
- W2337011191 hasConceptScore W2337011191C2778460671 @default.
- W2337011191 hasConceptScore W2337011191C2778917026 @default.
- W2337011191 hasConceptScore W2337011191C32909587 @default.
- W2337011191 hasConceptScore W2337011191C540031477 @default.
- W2337011191 hasConceptScore W2337011191C55493867 @default.
- W2337011191 hasConceptScore W2337011191C71240020 @default.
- W2337011191 hasConceptScore W2337011191C77562769 @default.
- W2337011191 hasIssue "2" @default.
- W2337011191 hasLocation W23370111911 @default.
- W2337011191 hasLocation W23370111912 @default.
- W2337011191 hasLocation W23370111913 @default.
- W2337011191 hasLocation W23370111914 @default.
- W2337011191 hasOpenAccess W2337011191 @default.
- W2337011191 hasPrimaryLocation W23370111911 @default.
- W2337011191 hasRelatedWork W1985037241 @default.
- W2337011191 hasRelatedWork W2022768087 @default.
- W2337011191 hasRelatedWork W2022804193 @default.
- W2337011191 hasRelatedWork W2041071840 @default.
- W2337011191 hasRelatedWork W2075370468 @default.
- W2337011191 hasRelatedWork W2088051949 @default.
- W2337011191 hasRelatedWork W2165422947 @default.