Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337131073> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2337131073 abstract "Micrococcal-nuclease digestion of rat liver nuclei selectively released mononucleosomes associated with ADP-ribosylated [Caplan, Ord & Stocken (1978) Biochem. J.174, 475–483] histone H1. Two classes of mononucleosome were detected, those that leaked out during digestion and those that were subsequently released by 5mm-sodium phosphate buffer (pH6.8)/0.2mm-NaEDTA. The former, from which histone H1 had been dissociated, contained 140-base-pair-length DNA and core histones;the latter contained core particles and mononucleosomes with histone H1 and 200-base-pair-length DNA. When normal liver nuclei were phosphorylated with [γ-32P]ATP, dissociated histone H1, which could be separated from core particles with Sephadex G-200, showed 32P uptake. 32P uptake into histones H2A and poly(ADP-ribosyl)ated H3 was appreciable in core particles, but was less evident in nucleosomes still containing histone H1. When [3H]-thymidine was given to partially hepatectomized rats in S-phase, 5–10min pulses in animals of over 300g body wt. showed the presence of high-specific-radioactivity DNA in released core particles and mononucleosomes compared with DNA retained in the nuclear pellets. Mononucleosomes from rat livers in S-phase with new, [3H]lysine-containing histones, had higher 32P incorporation in histones H1 and their core histones, than for di- or tri-nucleosomes. Thermal-denaturation properties of control and phosphorylated mononucleosomes and core particles were very similar; removal of histone H1 and non-histone chromosomal proteins in 0.5m-NaCl markedly increased the proportion of DNA ‘melting’ below 70°C." @default.
- W2337131073 created "2016-06-24" @default.
- W2337131073 creator A5089371074 @default.
- W2337131073 creator A5091307414 @default.
- W2337131073 date "1979-01-15" @default.
- W2337131073 modified "2023-10-18" @default.
- W2337131073 title "Nucleosomes from normal and regenerating rat liver" @default.
- W2337131073 cites W1491796581 @default.
- W2337131073 cites W1607046039 @default.
- W2337131073 cites W1775749144 @default.
- W2337131073 cites W1906197854 @default.
- W2337131073 cites W1996266432 @default.
- W2337131073 cites W1998423671 @default.
- W2337131073 cites W2003266932 @default.
- W2337131073 cites W2019725919 @default.
- W2337131073 cites W2021310901 @default.
- W2337131073 cites W2027628189 @default.
- W2337131073 cites W2036465299 @default.
- W2337131073 cites W2037059281 @default.
- W2337131073 cites W2079084847 @default.
- W2337131073 cites W2080494841 @default.
- W2337131073 cites W2084324725 @default.
- W2337131073 cites W2084997010 @default.
- W2337131073 cites W2086088658 @default.
- W2337131073 cites W2143944792 @default.
- W2337131073 cites W2155306457 @default.
- W2337131073 cites W2221620639 @default.
- W2337131073 cites W2404142871 @default.
- W2337131073 cites W74247517 @default.
- W2337131073 doi "https://doi.org/10.1042/bj1780173" @default.
- W2337131073 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1186494" @default.
- W2337131073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/435276" @default.
- W2337131073 hasPublicationYear "1979" @default.
- W2337131073 type Work @default.
- W2337131073 sameAs 2337131073 @default.
- W2337131073 citedByCount "6" @default.
- W2337131073 crossrefType "journal-article" @default.
- W2337131073 hasAuthorship W2337131073A5089371074 @default.
- W2337131073 hasAuthorship W2337131073A5091307414 @default.
- W2337131073 hasBestOaLocation W23371310732 @default.
- W2337131073 hasConcept C101152365 @default.
- W2337131073 hasConcept C12554922 @default.
- W2337131073 hasConcept C139024627 @default.
- W2337131073 hasConcept C153911025 @default.
- W2337131073 hasConcept C173681060 @default.
- W2337131073 hasConcept C552990157 @default.
- W2337131073 hasConcept C55493867 @default.
- W2337131073 hasConcept C60325843 @default.
- W2337131073 hasConcept C64927066 @default.
- W2337131073 hasConcept C84772758 @default.
- W2337131073 hasConcept C86803240 @default.
- W2337131073 hasConceptScore W2337131073C101152365 @default.
- W2337131073 hasConceptScore W2337131073C12554922 @default.
- W2337131073 hasConceptScore W2337131073C139024627 @default.
- W2337131073 hasConceptScore W2337131073C153911025 @default.
- W2337131073 hasConceptScore W2337131073C173681060 @default.
- W2337131073 hasConceptScore W2337131073C552990157 @default.
- W2337131073 hasConceptScore W2337131073C55493867 @default.
- W2337131073 hasConceptScore W2337131073C60325843 @default.
- W2337131073 hasConceptScore W2337131073C64927066 @default.
- W2337131073 hasConceptScore W2337131073C84772758 @default.
- W2337131073 hasConceptScore W2337131073C86803240 @default.
- W2337131073 hasLocation W23371310731 @default.
- W2337131073 hasLocation W23371310732 @default.
- W2337131073 hasLocation W23371310733 @default.
- W2337131073 hasLocation W23371310734 @default.
- W2337131073 hasOpenAccess W2337131073 @default.
- W2337131073 hasPrimaryLocation W23371310731 @default.
- W2337131073 hasRelatedWork W1854935287 @default.
- W2337131073 hasRelatedWork W1981397859 @default.
- W2337131073 hasRelatedWork W2014532072 @default.
- W2337131073 hasRelatedWork W2016891566 @default.
- W2337131073 hasRelatedWork W2022534851 @default.
- W2337131073 hasRelatedWork W2188640932 @default.
- W2337131073 hasRelatedWork W2337131073 @default.
- W2337131073 hasRelatedWork W293104292 @default.
- W2337131073 hasRelatedWork W3093247712 @default.
- W2337131073 hasRelatedWork W2395854792 @default.
- W2337131073 isParatext "false" @default.
- W2337131073 isRetracted "false" @default.
- W2337131073 magId "2337131073" @default.
- W2337131073 workType "article" @default.