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- W2337133719 abstract "Lawsonia inermis flowers were evaluated for chemical and biological properties for the first time. Extracts were prepared successively by hexane, chloroform and methanol. Phenolics (7.8-239.0g gallic acid equival ent/kg of dry mass), tannins (12.5148.5mg cathechin equivalent/kg of dry mass) and fl avonoids (36.2-43.75mg quercetin equivalent/kg of dry mass) were quantifie d. Methanol extract has a high antioxidant activity (IC 50 =8.5mg/L by DPPH assay and IC 50 =5mg/L by ABTS assay) and a good anti-inflammatory activity against 5-Lip oxygenase (IC 50 =49.33mg/L) compared to references. However, extracts exhibited a poor anti-Alzheimer and antidiabetic activities. Chloroform extract exhibited a higher anticancer activity (IC 50 =20mg/L). We observed high correlations between phenolics and flavonoids with antioxidant and anti-inflammatory activities ( 0.75<R2<0.97). Finally, a very good correlation between anti-inflammatory activity and antioxidant activity with R2=0.99. It may be interpreted that the greatest an ti-inflammatory activity was excreted by the best antioxidants extracts, which c ontain the high amounts of total phenolics." @default.
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- W2337133719 date "2015-01-01" @default.
- W2337133719 modified "2023-09-26" @default.
- W2337133719 title "Assessment of antioxidant, anti-inflammatory, anti-cholinesterase and cytotoxic activities of Henna ( Lawsonia inermis ) flowers" @default.
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