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• W2337226318 abstract "Back to table of contents Previous article Next article No AccessTryptophan metabolism in children with attentional deficit disorderPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.138.8.1082AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractThe authors present the first report, to their knowledge, of hyperserotonemia in children with attentional deficit disorder who had normal intelligence. Hyperserotonemic children had significantly lower levels of plasma total and protein-bound tryptophan and a higher percentage of free tryptophan than those with normal serotonin levels. Plasma kynurenine did not differ, suggesting that the hyperserotonemia is not due to a blockade of the kynurenine pathway but may reflect on increase in tissue tryptophan uptake and use. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byPotential Inflammatory Biomarker in Patients with Attention Deficit Hyperactivity Disorder27 October 2022 | International Journal of Molecular Sciences, Vol. 23, No. 21The role of tryptophan metabolic pathway in children with attention deficit hyperactivity disorder with and without comorbid oppositional defiant disorder and conduct disorderPsychiatry Research, Vol. 298Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker12 September 2019 | Scientific Reports, Vol. 9, No. 1Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide23 May 2018 | The World Journal of Biological Psychiatry, Vol. 33Serotonin Dysfunction, Aggressive Behavior, and Mental Illness: Exploring the Link Using a Dimensional Approach10 April 2017 | ACS Chemical Neuroscience, Vol. 8, No. 5Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 70Neurochemistry International, Vol. 82The Role of Kynurenine Pathway Metabolites in Neuropsychiatric DisordersADHD Attention Deficit and Hyperactivity Disorders, Vol. 6, No. 3Journal of Intellectual Disability Research, Vol. 31, No. 2Developmental Medicine & Child Neurology, Vol. 24, No. 3Expert Review of Neurotherapeutics, Vol. 7, No. 10, Vol. 98Journal of Addictions Nursing, Vol. 12, No. 3-4Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 34, No. 1, Vol. 2Journal of Child and Adolescent Psychopharmacology, Vol. 3, No. 1The Functional Approach of Biological Research in PsychiatryAmerican Journal of Medical Genetics, Vol. 36, No. 4International Journal of Biometeorology, Vol. 34, No. 16 - Le recherches biochimiques dans l’autisme infantileSerotonin and measured intelligenceJournal of Autism and Developmental Disorders, Vol. 18, No. 4British Journal of Psychiatry, Vol. 153, No. S3Psychophysiological Effects of Methylphenidate (Ritalin)1 September 2016 | Psychological Reports, Vol. 61, No. 1Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 26, No. 5Journal of Child Psychology and Psychiatry, Vol. 28, No. 6Pemoline and urinary excretion of catecholamines and indoleamines in children with attention deficit disorder1 April 2006 | American Journal of Psychiatry, Vol. 143, No. 3Environment International, Vol. 12, No. 1-4Journal of the American Academy of Child Psychiatry, Vol. 25, No. 4BibliographiePostgraduate Medicine, Vol. 78, No. 2Nutritional Therapy in Children Volume 138Issue 8 August 1981Pages 1082-1085 Metrics PDF download History Published online 1 April 2006 Published in print 1 August 1981" @default.
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