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• W2337245162 abstract "Background: Medicinal plants are used by many ethnic groups as a source of medicine for the treatment of various ailments in both&#x0D; humans and domestic animals. These plants produce secondary metabolites that have antimicrobial properties, thus screening of&#x0D; medicinal plants provide another alternative for producing chemical fungicides that are relatively non-toxic and cost-effective.&#x0D; Materials and methods: Leaf extracts of selected South African plant species (Bucida buceras, Breonadia salicina, Harpephyllum&#x0D; caffrum, Olinia ventosa, Vangueria infausta and Xylotheca kraussiana) were investigated for activity against selected&#x0D; phytopathogenic fungi (Aspergillus niger, Aspergillus parasiticus, Colletotricum gloeosporioides, Penicillium janthinellum, P.&#x0D; expansum, Trichoderma harzianum and Fusarium oxysporum). These plant fungal pathogens causes major economic losses in fruit&#x0D; industry such as blue rot on nectaries and postharvest disease in citrus. Plant species were selected from 600 evaluated inter alia,&#x0D; against two animal fungal pathogens (Candida albicans and Cryptococcus neoformans). Antioxidant activity of the selected plant&#x0D; extracts were investigated using a qualitative assay (2, 2-diphenyl-1-picrylhydrazyl (DPPH)). Bioautography assay was used to&#x0D; determine the number of antifungal compounds in plant extracts.&#x0D; Results: All plant extracts were active against the selected plant phytopathogenic fungi. Moreover, Bucida buceras had the best&#x0D; antifungal activity against four of the fungi, with minimum inhibitory concentration (MIC) values as low as 0.02 mg/ml and 0.08&#x0D; mg/ml against P. expansum, P. janthinellum, T. harzianum and F. oxysporum. The plant extracts of five plant species did not possess&#x0D; strong antioxidant activity. However, methanol extract of X. kraussiana was the most active radical scavenger in the DPPH assay&#x0D; amongst the six medicinal plants screened. No antifungal compounds were observed in some of the plant extracts with good&#x0D; antifungal activity as shown in the microdilution assay, indicating possible synergism between the separated metabolites.&#x0D; Conclusion: The results showed that acetone was the best extractant. Furthermore, our findings also confirm the traditional use of&#x0D; Breonadia salicina and demonstrate the potential value of developing biopesticides from plants." @default.
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• W2337245162 date "2016-07-03" @default.
• W2337245162 modified "2023-10-06" @default.
• W2337245162 title "ANTIOXIDANT AND ANTIFUNGAL ACTIVITY OF SELECTED MEDICINAL PLANT EXTRACTS AGAINST PHYTOPATHOGENIC FUNGI" @default.
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• W2337245162 doi "https://doi.org/10.21010/ajtcam.v13i4.28" @default.
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