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• W2337321963 abstract "thrombus formation. Until this process has been fully established, the non-adherent, disorganized thrombus may propagate and/or embolize. Not all venous thrombi pose equal embolic risk. Studies have shown that isolated calf vein thrombi carry a limited risk of pulmonary embolism. 8 Furthermore, studies have suggested that isolated calf vein thrombi are smaller and do not cause significant morbidity or mortality if they embolize. Contradictory evidence from several other studies has indicated that isolated calf vein thrombi do embolize and that propagation proximally may occur rapidly leading to fatal pulmonary embolism. 9,10 The current diagnostic and therapeutic management of DVT is influenced strongly by the different risks assigned to proximal and calf vein thrombi. Most clinicians do not anticoagulate patients with isolated calf vein thrombosis unless objective evidence of proximal extension is found on serial evaluation. Exceptions may be made for highrisk patients. Pulmonary embolism is best viewed as a complication of DVT. The two conditions often co-exist. Asymptomatic DVT is found in 40% to 50% of patients with PE. Forty percent of patients with DVT have clinically silent PE based on objective studies. 11" @default.
• W2337321963 created "2016-06-24" @default.
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• W2337321963 date "2002-02-01" @default.
• W2337321963 modified "2023-09-23" @default.
• W2337321963 title "The Role of D-Dimer in the Diagnosis of Venous Thromboembolism" @default.
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