FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337377655> ?p ?o ?g. }

• W2337377655 endingPage "19162" @default.
• W2337377655 startingPage "19155" @default.
• W2337377655 abstract "Recent studies revealed common genetic risks for both viral bronchiolitis and asthma. Genome-wide association studies revealed that rs7216389 in the ORMDL3 gene is associated with childhood asthma. We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibility/viral findings among 247 infant bronchiolitis cases and 190 healthy controls. We genotyped single nucleotide polymorphisms by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry and detected respiratory viruses with multiplex reverse transcriptase-polymerase chain reaction. Only the genotype and allele frequencies of rs7216389 significantly differed between bronchiolitis and controls. The frequencies of the TT homozygote and the T allele of rs7216389 were significantly higher in the bronchiolitis patients (P = 0.0325; P = 0.0089, respectively). Polymorphisms were not associated with bronchiolitis severity. Cases were further stratified by viral infection, but no significant differences in the ORMDL3 genotype between the virus-detected group (e.g., respiratory syncytial virus alone, respiratory virus alone, virus detected) and no-virus-detected group were observed. Bronchiolitis is associated with the ORMDL3 gene in Chinese children, and there were no significant associations between genetic variations and disease severity or respiratory viruses. The TT homozygote and the T allele of rs7216389 in ORMDL3 increased bronchiolitis risk. The rs7216389 polymorphism may be a predictor for identifying infants with predisposition to virus-induced wheezing to persistent asthma." @default.
• W2337377655 created "2016-06-24" @default.
• W2337377655 creator A5005636099 @default.
• W2337377655 creator A5020426022 @default.
• W2337377655 creator A5045435869 @default.
• W2337377655 creator A5047420372 @default.
• W2337377655 creator A5057310427 @default.
• W2337377655 creator A5081715749 @default.
• W2337377655 date "2015-01-01" @default.
• W2337377655 modified "2023-10-16" @default.
• W2337377655 title "ORMDL3 variants associated with bronchiolitis susceptibility in a Chinese population" @default.
• W2337377655 cites W1488184011 @default.
• W2337377655 cites W1883135246 @default.
• W2337377655 cites W1972635337 @default.
• W2337377655 cites W1999604173 @default.
• W2337377655 cites W2008599922 @default.
• W2337377655 cites W2012568595 @default.
• W2337377655 cites W2014777411 @default.
• W2337377655 cites W2027411718 @default.
• W2337377655 cites W2048510189 @default.
• W2337377655 cites W2053048205 @default.
• W2337377655 cites W2062661663 @default.
• W2337377655 cites W2083060892 @default.
• W2337377655 cites W2083778924 @default.
• W2337377655 cites W2091514197 @default.
• W2337377655 cites W2118364170 @default.
• W2337377655 cites W2125178177 @default.
• W2337377655 cites W2130504874 @default.
• W2337377655 cites W2140479418 @default.
• W2337377655 cites W2140981885 @default.
• W2337377655 cites W2145762862 @default.
• W2337377655 cites W2146101869 @default.
• W2337377655 cites W2150387021 @default.
• W2337377655 cites W2157794811 @default.
• W2337377655 cites W2159826008 @default.
• W2337377655 cites W2170115663 @default.
• W2337377655 cites W2170226324 @default.
• W2337377655 cites W2172160537 @default.
• W2337377655 cites W2325690509 @default.
• W2337377655 doi "https://doi.org/10.4238/2015.december.29.25" @default.
• W2337377655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26782568" @default.
• W2337377655 hasPublicationYear "2015" @default.
• W2337377655 type Work @default.
• W2337377655 sameAs 2337377655 @default.
• W2337377655 citedByCount "2" @default.
• W2337377655 countsByYear W23373776552019 @default.
• W2337377655 countsByYear W23373776552022 @default.
• W2337377655 crossrefType "journal-article" @default.
• W2337377655 hasAuthorship W2337377655A5005636099 @default.
• W2337377655 hasAuthorship W2337377655A5020426022 @default.
• W2337377655 hasAuthorship W2337377655A5045435869 @default.
• W2337377655 hasAuthorship W2337377655A5047420372 @default.
• W2337377655 hasAuthorship W2337377655A5057310427 @default.
• W2337377655 hasAuthorship W2337377655A5081715749 @default.
• W2337377655 hasBestOaLocation W23373776551 @default.
• W2337377655 hasConcept C104317684 @default.
• W2337377655 hasConcept C135763542 @default.
• W2337377655 hasConcept C153209595 @default.
• W2337377655 hasConcept C159047783 @default.
• W2337377655 hasConcept C180754005 @default.
• W2337377655 hasConcept C203014093 @default.
• W2337377655 hasConcept C2522874641 @default.
• W2337377655 hasConcept C2776042228 @default.
• W2337377655 hasConcept C2778821649 @default.
• W2337377655 hasConcept C2908647359 @default.
• W2337377655 hasConcept C54355233 @default.
• W2337377655 hasConcept C67636389 @default.
• W2337377655 hasConcept C71924100 @default.
• W2337377655 hasConcept C86803240 @default.
• W2337377655 hasConcept C99454951 @default.
• W2337377655 hasConceptScore W2337377655C104317684 @default.
• W2337377655 hasConceptScore W2337377655C135763542 @default.
• W2337377655 hasConceptScore W2337377655C153209595 @default.
• W2337377655 hasConceptScore W2337377655C159047783 @default.
• W2337377655 hasConceptScore W2337377655C180754005 @default.
• W2337377655 hasConceptScore W2337377655C203014093 @default.
• W2337377655 hasConceptScore W2337377655C2522874641 @default.
• W2337377655 hasConceptScore W2337377655C2776042228 @default.
• W2337377655 hasConceptScore W2337377655C2778821649 @default.
• W2337377655 hasConceptScore W2337377655C2908647359 @default.
• W2337377655 hasConceptScore W2337377655C54355233 @default.
• W2337377655 hasConceptScore W2337377655C67636389 @default.
• W2337377655 hasConceptScore W2337377655C71924100 @default.
• W2337377655 hasConceptScore W2337377655C86803240 @default.
• W2337377655 hasConceptScore W2337377655C99454951 @default.
• W2337377655 hasIssue "4" @default.
• W2337377655 hasLocation W23373776551 @default.
• W2337377655 hasLocation W23373776552 @default.
• W2337377655 hasOpenAccess W2337377655 @default.
• W2337377655 hasPrimaryLocation W23373776551 @default.
• W2337377655 hasRelatedWork W1190776263 @default.
• W2337377655 hasRelatedWork W1487857142 @default.
• W2337377655 hasRelatedWork W1492270877 @default.
• W2337377655 hasRelatedWork W2002092803 @default.
• W2337377655 hasRelatedWork W2103125327 @default.
• W2337377655 hasRelatedWork W2372596039 @default.
• W2337377655 hasRelatedWork W2382381422 @default.
• W2337377655 hasRelatedWork W3055258070 @default.

• next