FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337505067> ?p ?o ?g. }

• W2337505067 endingPage "55" @default.
• W2337505067 startingPage "347" @default.
• W2337505067 abstract "The orientation of the anterior-posterior (A-P) axis was examined in gastrula-stage Hnf3beta, Otx2 and Lim1 null mutant embryos that display defective axis development. In situ hybridization analysis of the expression pattern of genes associated with the posterior germ layer tissues and the primitive streak (T, Wnt3 and Fgf8) and anterior endoderm (Cer1 and Sox17) revealed that the A-P axis of mutant embryos remains aligned with the proximo-distal plane of the gastrula. Further analysis revealed that cells which express Chrd activity are either absent in Hnf3beta mutant embryos or localised in heterotopic sites in Lim1 and Otx2 null mutants. Lim1-expressing cells are present in the Hnf3beta mutant embryo albeit in heterotopic sites. In all three mutants, Gsc-expressing cells are missing from the anterior mesendoderm. These findings suggest that although some cells with organizer activity may be present in the mutant embryo, they are not properly localised and fail to contribute to the axial mesoderm of the head. By contrast, in T/T mutant embryos that display normal head fold development, the expression domains of organizer, primitive streak and anterior endoderm genes are regionalised correctly in the gastrula." @default.
• W2337505067 created "2016-06-24" @default.
• W2337505067 creator A5005311973 @default.
• W2337505067 creator A5049883489 @default.
• W2337505067 creator A5052145237 @default.
• W2337505067 creator A5066410172 @default.
• W2337505067 creator A5080788580 @default.
• W2337505067 date "2001-01-01" @default.
• W2337505067 modified "2023-09-23" @default.
• W2337505067 title "Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity." @default.
• W2337505067 cites W1541821200 @default.
• W2337505067 cites W1542932778 @default.
• W2337505067 cites W1616656317 @default.
• W2337505067 cites W1680418198 @default.
• W2337505067 cites W1829700783 @default.
• W2337505067 cites W1922106993 @default.
• W2337505067 cites W1958452436 @default.
• W2337505067 cites W1966300079 @default.
• W2337505067 cites W1970489582 @default.
• W2337505067 cites W1979549057 @default.
• W2337505067 cites W1984696112 @default.
• W2337505067 cites W1998023087 @default.
• W2337505067 cites W2002549741 @default.
• W2337505067 cites W2003028861 @default.
• W2337505067 cites W2006853616 @default.
• W2337505067 cites W2008777486 @default.
• W2337505067 cites W2013154305 @default.
• W2337505067 cites W2022787977 @default.
• W2337505067 cites W2030656510 @default.
• W2337505067 cites W2043684972 @default.
• W2337505067 cites W2049326750 @default.
• W2337505067 cites W2057375692 @default.
• W2337505067 cites W2063778808 @default.
• W2337505067 cites W2079276277 @default.
• W2337505067 cites W2094145003 @default.
• W2337505067 cites W2098890132 @default.
• W2337505067 cites W2107141327 @default.
• W2337505067 cites W2108946209 @default.
• W2337505067 cites W2109052299 @default.
• W2337505067 cites W2110118328 @default.
• W2337505067 cites W2111935536 @default.
• W2337505067 cites W2112302721 @default.
• W2337505067 cites W2120142812 @default.
• W2337505067 cites W2127510589 @default.
• W2337505067 cites W2131340112 @default.
• W2337505067 cites W2137854993 @default.
• W2337505067 cites W2148354523 @default.
• W2337505067 cites W2150240495 @default.
• W2337505067 cites W2158470573 @default.
• W2337505067 cites W2165695219 @default.
• W2337505067 cites W2183066763 @default.
• W2337505067 cites W2187208469 @default.
• W2337505067 cites W2189351183 @default.
• W2337505067 cites W2406464272 @default.
• W2337505067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11291865" @default.
• W2337505067 hasPublicationYear "2001" @default.
• W2337505067 type Work @default.
• W2337505067 sameAs 2337505067 @default.
• W2337505067 citedByCount "11" @default.
• W2337505067 countsByYear W23375050672016 @default.
• W2337505067 countsByYear W23375050672022 @default.
• W2337505067 crossrefType "journal-article" @default.
• W2337505067 hasAuthorship W2337505067A5005311973 @default.
• W2337505067 hasAuthorship W2337505067A5049883489 @default.
• W2337505067 hasAuthorship W2337505067A5052145237 @default.
• W2337505067 hasAuthorship W2337505067A5066410172 @default.
• W2337505067 hasAuthorship W2337505067A5080788580 @default.
• W2337505067 hasConcept C104317684 @default.
• W2337505067 hasConcept C105702510 @default.
• W2337505067 hasConcept C107459253 @default.
• W2337505067 hasConcept C129536746 @default.
• W2337505067 hasConcept C143065580 @default.
• W2337505067 hasConcept C145103041 @default.
• W2337505067 hasConcept C150194340 @default.
• W2337505067 hasConcept C153911025 @default.
• W2337505067 hasConcept C18155467 @default.
• W2337505067 hasConcept C191548132 @default.
• W2337505067 hasConcept C196843134 @default.
• W2337505067 hasConcept C203014093 @default.
• W2337505067 hasConcept C204232928 @default.
• W2337505067 hasConcept C2777164004 @default.
• W2337505067 hasConcept C2780915607 @default.
• W2337505067 hasConcept C54355233 @default.
• W2337505067 hasConcept C66518211 @default.
• W2337505067 hasConcept C75059768 @default.
• W2337505067 hasConcept C81439078 @default.
• W2337505067 hasConcept C86803240 @default.
• W2337505067 hasConcept C87073359 @default.
• W2337505067 hasConcept C95444343 @default.
• W2337505067 hasConceptScore W2337505067C104317684 @default.
• W2337505067 hasConceptScore W2337505067C105702510 @default.
• W2337505067 hasConceptScore W2337505067C107459253 @default.
• W2337505067 hasConceptScore W2337505067C129536746 @default.
• W2337505067 hasConceptScore W2337505067C143065580 @default.
• W2337505067 hasConceptScore W2337505067C145103041 @default.
• W2337505067 hasConceptScore W2337505067C150194340 @default.
• W2337505067 hasConceptScore W2337505067C153911025 @default.
• W2337505067 hasConceptScore W2337505067C18155467 @default.

• next