FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337506121> ?p ?o ?g. }

• W2337506121 endingPage "550" @default.
• W2337506121 startingPage "543" @default.
• W2337506121 abstract "Multistep hepatocarcinogenesis progresses from dysplastic nodules to early hepatocellular carcinoma ( eHCC ) and to advanced HCC . The aim of the present study was to investigate the detailed histopathological features of eHCC . We investigated 66 small vaguely nodular lesions resected from 40 patients. The degree of cellular and structural atypia and stromal invasion were assessed. The immunohistochemical expression of HCC ‐related markers adenylate cyclase‐associated protein 2 ( CAP 2), heat shock protein 70 ( HSP 70), Bmi‐1, CD 34 and h‐caldesmon were evaluated. Of the 66 nodules, 10 were diagnosed as low‐grade dysplastic nodules ( LGDN ), 10 as high‐grade dysplastic nodules ( HGDN ) and 46 as eHCC . Among the 46 eHCC , 18 nodules (39.1%) showed marked stromal invasion and/or the presence of the scirrhous component and were subclassified as high‐grade eHCC ( HG e HCC ). The remaining 28 eHCC , which lacked these features, were subclassified as low‐grade eHCC ( LG e HCC ) and were examined further. HG e HCC showed high levels of cellular and structural atypia and large tumor size. The immunohistochemical expression of CAP 2 and the area of sinusoidal vascularization showed increases from LGDN to HG e HCC . The density of arterial tumor vessels was high in HG e HCC compared with other nodule types. Cluster analysis of these parameters subclassified 65 nodules into HG e HCC ‐dominant, LG e HCC and HGDN ‐dominant, and LGDN ‐dominant groups. These results indicate the increased malignant potential of HG e HCC and suggest that it is already a transitional stage to advanced HCC . We consider that our grading classification system may be valuable for considering treatment strategies for eHCC around 2 cm in diameter." @default.
• W2337506121 created "2016-06-24" @default.
• W2337506121 creator A5010688236 @default.
• W2337506121 creator A5012979592 @default.
• W2337506121 creator A5018112691 @default.
• W2337506121 creator A5029342937 @default.
• W2337506121 creator A5056642819 @default.
• W2337506121 creator A5059497904 @default.
• W2337506121 creator A5074189829 @default.
• W2337506121 creator A5075771983 @default.
• W2337506121 creator A5084805424 @default.
• W2337506121 creator A5091811703 @default.
• W2337506121 date "2016-03-18" @default.
• W2337506121 modified "2023-10-14" @default.
• W2337506121 title "Early hepatocellular carcinoma with high‐grade atypia in small vaguely nodular lesions" @default.
• W2337506121 cites W1964319630 @default.
• W2337506121 cites W1968147880 @default.
• W2337506121 cites W1972956861 @default.
• W2337506121 cites W1977485345 @default.
• W2337506121 cites W2058579700 @default.
• W2337506121 cites W2060770070 @default.
• W2337506121 cites W2084202175 @default.
• W2337506121 cites W2084262557 @default.
• W2337506121 cites W2101270576 @default.
• W2337506121 cites W2108361563 @default.
• W2337506121 cites W2123431135 @default.
• W2337506121 cites W2123992522 @default.
• W2337506121 cites W2145198850 @default.
• W2337506121 cites W2146284084 @default.
• W2337506121 cites W2147541435 @default.
• W2337506121 cites W2158738298 @default.
• W2337506121 cites W2253298865 @default.
• W2337506121 cites W2525980773 @default.
• W2337506121 cites W4250410090 @default.
• W2337506121 cites W4368205260 @default.
• W2337506121 doi "https://doi.org/10.1111/cas.12893" @default.
• W2337506121 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4832853" @default.
• W2337506121 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26797961" @default.
• W2337506121 hasPublicationYear "2016" @default.
• W2337506121 type Work @default.
• W2337506121 sameAs 2337506121 @default.
• W2337506121 citedByCount "8" @default.
• W2337506121 countsByYear W23375061212017 @default.
• W2337506121 countsByYear W23375061212018 @default.
• W2337506121 countsByYear W23375061212020 @default.
• W2337506121 countsByYear W23375061212021 @default.
• W2337506121 countsByYear W23375061212022 @default.
• W2337506121 countsByYear W23375061212023 @default.
• W2337506121 crossrefType "journal-article" @default.
• W2337506121 hasAuthorship W2337506121A5010688236 @default.
• W2337506121 hasAuthorship W2337506121A5012979592 @default.
• W2337506121 hasAuthorship W2337506121A5018112691 @default.
• W2337506121 hasAuthorship W2337506121A5029342937 @default.
• W2337506121 hasAuthorship W2337506121A5056642819 @default.
• W2337506121 hasAuthorship W2337506121A5059497904 @default.
• W2337506121 hasAuthorship W2337506121A5074189829 @default.
• W2337506121 hasAuthorship W2337506121A5075771983 @default.
• W2337506121 hasAuthorship W2337506121A5084805424 @default.
• W2337506121 hasAuthorship W2337506121A5091811703 @default.
• W2337506121 hasBestOaLocation W23375061211 @default.
• W2337506121 hasConcept C126322002 @default.
• W2337506121 hasConcept C142724271 @default.
• W2337506121 hasConcept C16930146 @default.
• W2337506121 hasConcept C204232928 @default.
• W2337506121 hasConcept C2777546739 @default.
• W2337506121 hasConcept C2778019345 @default.
• W2337506121 hasConcept C2781283455 @default.
• W2337506121 hasConcept C71924100 @default.
• W2337506121 hasConcept C90924648 @default.
• W2337506121 hasConceptScore W2337506121C126322002 @default.
• W2337506121 hasConceptScore W2337506121C142724271 @default.
• W2337506121 hasConceptScore W2337506121C16930146 @default.
• W2337506121 hasConceptScore W2337506121C204232928 @default.
• W2337506121 hasConceptScore W2337506121C2777546739 @default.
• W2337506121 hasConceptScore W2337506121C2778019345 @default.
• W2337506121 hasConceptScore W2337506121C2781283455 @default.
• W2337506121 hasConceptScore W2337506121C71924100 @default.
• W2337506121 hasConceptScore W2337506121C90924648 @default.
• W2337506121 hasFunder F4320320912 @default.
• W2337506121 hasFunder F4320321945 @default.
• W2337506121 hasIssue "4" @default.
• W2337506121 hasLocation W23375061211 @default.
• W2337506121 hasLocation W23375061212 @default.
• W2337506121 hasLocation W23375061213 @default.
• W2337506121 hasOpenAccess W2337506121 @default.
• W2337506121 hasPrimaryLocation W23375061211 @default.
• W2337506121 hasRelatedWork W2010061202 @default.
• W2337506121 hasRelatedWork W2138198379 @default.
• W2337506121 hasRelatedWork W2165306189 @default.
• W2337506121 hasRelatedWork W2273901811 @default.
• W2337506121 hasRelatedWork W2359625386 @default.
• W2337506121 hasRelatedWork W2381576875 @default.
• W2337506121 hasRelatedWork W2423002161 @default.
• W2337506121 hasRelatedWork W2766588635 @default.
• W2337506121 hasRelatedWork W2980418058 @default.
• W2337506121 hasRelatedWork W3029220886 @default.
• W2337506121 hasVolume "107" @default.
• W2337506121 isParatext "false" @default.

• next