FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337514173> ?p ?o ?g. }

• W2337514173 endingPage "11" @default.
• W2337514173 startingPage "706" @default.
• W2337514173 abstract "To evaluate the expression of epidermal growth factor receptor (EGFR), p53, p21 and thymidylate synthase (TS) in a pretherapy biopsy specimen of locally advanced squamous cell esophageal cancer and correlate these markers with response to neoadjuvant chemoradiotherapy.Sixty-two patients with histopathologically proven locally advanced (T3 or greater) squamous cell esophageal cancer were enrolled. The expression of EGRF, p53, p21 and TS markers was assessed with immunohistochemistry. Semiquantitative assessment of expression of these markers was performed based on the percent of the stained cells. Radiotherapy (45-50.4 Gy) was delivered concomitantly with 5-fluorouracil (5-FU)/leucovorin (LV)/cisplatin (CIS) chemotherapy. Five to 6 weeks after chemoradiation, response to treatment was assessed. Medically fit and operable patients were operated. The resected material underwent histopathological evaluation of tumor expansion, histological classification after initial multimodality treatment (yp TNM), residual status and tumor regression grade (TRG).Out of 62 patients enrolled, 41 (66%) were evaluated for molecular markers. Clinical response rate was 43.9%. Out of 41 patients, 12 (29%) underwent surgery. TRG 1 was noted in 58% of the patients. In a pretherapy tumor specimen, positive expression was noted in 80, 90, 80 and 71% for EGFR, p53, p21 and TS, respectively. We noted no statistically significant difference neither between tumor marker expression and clinical response to chemoradiation, nor between tumor marker expression and TRG.We registered no difference in response to treatment between EGFR, TS, p21 and p53 positive and negative staining." @default.
• W2337514173 created "2016-06-24" @default.
• W2337514173 creator A5006265180 @default.
• W2337514173 creator A5017834537 @default.
• W2337514173 creator A5023046965 @default.
• W2337514173 creator A5036110395 @default.
• W2337514173 creator A5072430373 @default.
• W2337514173 creator A5079170101 @default.
• W2337514173 date "2013-01-22" @default.
• W2337514173 modified "2023-09-23" @default.
• W2337514173 title "Is there a correlation between molecular markers and response to neoadjuvant chemoradiotherapy in locally advanced squamous cell esophageal cancer?" @default.
• W2337514173 cites W1969183945 @default.
• W2337514173 cites W1977468182 @default.
• W2337514173 cites W1991172758 @default.
• W2337514173 cites W2004394004 @default.
• W2337514173 cites W2004898879 @default.
• W2337514173 cites W2012673254 @default.
• W2337514173 cites W2025560151 @default.
• W2337514173 cites W2026511198 @default.
• W2337514173 cites W2027216527 @default.
• W2337514173 cites W2040583755 @default.
• W2337514173 cites W2044433058 @default.
• W2337514173 cites W2063298165 @default.
• W2337514173 cites W2070884133 @default.
• W2337514173 cites W2074990506 @default.
• W2337514173 cites W2080344286 @default.
• W2337514173 cites W2117223681 @default.
• W2337514173 cites W2127996441 @default.
• W2337514173 cites W2136419286 @default.
• W2337514173 cites W2136935697 @default.
• W2337514173 cites W2139174810 @default.
• W2337514173 cites W2139248078 @default.
• W2337514173 cites W2140625837 @default.
• W2337514173 cites W2147117977 @default.
• W2337514173 cites W2184515929 @default.
• W2337514173 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23335529" @default.
• W2337514173 hasPublicationYear "2013" @default.
• W2337514173 type Work @default.
• W2337514173 sameAs 2337514173 @default.
• W2337514173 citedByCount "3" @default.
• W2337514173 countsByYear W23375141732014 @default.
• W2337514173 countsByYear W23375141732020 @default.
• W2337514173 crossrefType "journal-article" @default.
• W2337514173 hasAuthorship W2337514173A5006265180 @default.
• W2337514173 hasAuthorship W2337514173A5017834537 @default.
• W2337514173 hasAuthorship W2337514173A5023046965 @default.
• W2337514173 hasAuthorship W2337514173A5036110395 @default.
• W2337514173 hasAuthorship W2337514173A5072430373 @default.
• W2337514173 hasAuthorship W2337514173A5079170101 @default.
• W2337514173 hasConcept C121608353 @default.
• W2337514173 hasConcept C123321153 @default.
• W2337514173 hasConcept C126322002 @default.
• W2337514173 hasConcept C142724271 @default.
• W2337514173 hasConcept C143998085 @default.
• W2337514173 hasConcept C204232928 @default.
• W2337514173 hasConcept C2775934546 @default.
• W2337514173 hasConcept C2776694085 @default.
• W2337514173 hasConcept C2778239845 @default.
• W2337514173 hasConcept C2778292576 @default.
• W2337514173 hasConcept C2778424827 @default.
• W2337514173 hasConcept C2779742542 @default.
• W2337514173 hasConcept C2780456651 @default.
• W2337514173 hasConcept C509974204 @default.
• W2337514173 hasConcept C530470458 @default.
• W2337514173 hasConcept C71924100 @default.
• W2337514173 hasConceptScore W2337514173C121608353 @default.
• W2337514173 hasConceptScore W2337514173C123321153 @default.
• W2337514173 hasConceptScore W2337514173C126322002 @default.
• W2337514173 hasConceptScore W2337514173C142724271 @default.
• W2337514173 hasConceptScore W2337514173C143998085 @default.
• W2337514173 hasConceptScore W2337514173C204232928 @default.
• W2337514173 hasConceptScore W2337514173C2775934546 @default.
• W2337514173 hasConceptScore W2337514173C2776694085 @default.
• W2337514173 hasConceptScore W2337514173C2778239845 @default.
• W2337514173 hasConceptScore W2337514173C2778292576 @default.
• W2337514173 hasConceptScore W2337514173C2778424827 @default.
• W2337514173 hasConceptScore W2337514173C2779742542 @default.
• W2337514173 hasConceptScore W2337514173C2780456651 @default.
• W2337514173 hasConceptScore W2337514173C509974204 @default.
• W2337514173 hasConceptScore W2337514173C530470458 @default.
• W2337514173 hasConceptScore W2337514173C71924100 @default.
• W2337514173 hasIssue "4" @default.
• W2337514173 hasLocation W23375141731 @default.
• W2337514173 hasOpenAccess W2337514173 @default.
• W2337514173 hasPrimaryLocation W23375141731 @default.
• W2337514173 hasRelatedWork W1979838159 @default.
• W2337514173 hasRelatedWork W1986634144 @default.
• W2337514173 hasRelatedWork W1992836159 @default.
• W2337514173 hasRelatedWork W2002209175 @default.
• W2337514173 hasRelatedWork W2045565271 @default.
• W2337514173 hasRelatedWork W2138402953 @default.
• W2337514173 hasRelatedWork W2379292808 @default.
• W2337514173 hasRelatedWork W2404042595 @default.
• W2337514173 hasRelatedWork W2608336355 @default.
• W2337514173 hasRelatedWork W2096456165 @default.
• W2337514173 hasVolume "17" @default.
• W2337514173 isParatext "false" @default.
• W2337514173 isRetracted "false" @default.

• next