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- W2337644580 abstract "Background While “string-of-beads” coronary Fibromuscular Dysplasia (FMD) is rare, recent works suggest that Spontaneous Coronary Artery Dissection (SCAD) (a cardiac complication typically occurring in young women with few risk factors) is due to FMD in >80% of cases. Other aspects suggestive of coronary FMD include smooth narrowing, intramural hematoma and tortuosity. The management of FMD-related coronary events differs from that of atherosclerotic events: (I) conservative treatment is the preferred option; (II) screening for extra-coronary FMD lesions should be considered. Unfortunately, most interventional cardiologists are not familiar with this entity and many cases are overlooked. The aim of this study was to look for the prevalence and clinical presentation of coronary FMD in young women admitted to the Cath Lab for an acute coronary event. Methods Coronary angiograms of all women aged Results Aspects suggestive of coronary FMD were identified in 19/336 patients (mean age: 42 ± 6.7 years). The predominant presentation was suspected coronary artery dissection (12 patients), either isolated (n = 5) or associated with smooth narrowing (n = 4), tortuosity (n = 2) or intramural hematoma (n = 1). In an additional 7 patients, aspects of smooth narrowing (n = 5) or tortuous coronary vessels (n = 2) were identified in the absence of direct evidence of dissection. Compared to 19 sex- and age-matched controls with atherosclerotic disease, the prevalence of diabetes was significantly lower (11 vs 58%, p = 0.002), and the prevalence of smoking higher (63 vs 16%, p = 0.003). No difference in the prevalence of hypertension (47 vs 32%, p = 0.3) or dyslipidemia (42 vs 53%, p = 0.5) was found. Conclusions In this retrospective series of women aged" @default.
- W2337644580 created "2016-06-24" @default.
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- W2337644580 date "2015-12-01" @default.
- W2337644580 modified "2023-09-25" @default.
- W2337644580 title "CO-02: Prevalence and characteristics of coronary fibromuscular dysplasia in women aged <50 years admitted for an acute coronary event" @default.
- W2337644580 doi "https://doi.org/10.1016/s0003-3928(16)30002-6" @default.
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