FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2337878444> ?p ?o ?g. }

• W2337878444 endingPage "S245" @default.
• W2337878444 startingPage "S241" @default.
• W2337878444 abstract "Introduction Fat grafting for breast cancer (BrCa) reconstruction and breast augmentation has become increasingly more popular. A major area of debate and controversy is the effect of adipose-derived stem cells (ASCs) on remnant or undetected BrCa cells. We investigate the in vitro response of BrCa to ASCs in a coculture model with regards to cell migration. Methods The study was approved by the institutional review board. BrCa and adipose tissue specimens either from subcutaneous breast tissue or abdominal lipoaspirate were obtained from the same patient. BrCa cells and ASCs were harvested with either explant culture and/or enzymatic digestion. Tissues were grown in cell culture flasks until adequate cell libraries were established. Adipose-derived stem cells from adipose specimens were characterized with flow cytometry. Immunofluorescence (IF) staining of the initial cell population harvested from the BrCa specimens confirmed the presence of CD24, an epithelial marker of BrCa. A homogenous CD 24+/CD 90− BrCa cell population was obtained with flowcytometric cell sorting. The in vitro migration of BrCa cells was examined in coculture with and without ASCs. Results Adipose-derived stem cells harvested from the adipose specimens were positive for mesenchymal stem cell markers CD 105, CD 90, CD 73, and CD 44 and negative for lymphocyte cell marker CD 34 and leukocyte marker CD 45. The percentage of the CD 24+/CD 90− BrCa cells in the initial cell population harvested from BrCa specimens was 0.61%. The BrCa cells morphologically had large nuclei and small cytoplasm in clusters under the light microscope, suggesting a cancer cell phenotype. CD 24 expression on the surface of BrCa cells was confirmed with IF staining. The number of BrCa cells migrated in ASCs coculture was approximately 10 times higher than the number of BrCa cells migrated in BrCa cell only cultures. Conclusions Adipose-derived stem cells significantly increase the migration capacity of BrCa cells in vitro in cocultures. This should be taken into consideration when performing fat grafting to the breast especially in patients with a history of BrCa or strong family history of BrCa." @default.
• W2337878444 created "2016-06-24" @default.
• W2337878444 creator A5011832483 @default.
• W2337878444 creator A5017359925 @default.
• W2337878444 creator A5042267289 @default.
• W2337878444 creator A5056091409 @default.
• W2337878444 creator A5081546351 @default.
• W2337878444 date "2016-05-01" @default.
• W2337878444 modified "2023-09-29" @default.
• W2337878444 title "In Vitro Effects of Adipose-Derived Stem Cells on Breast Cancer Cells Harvested From the Same Patient" @default.
• W2337878444 cites W1977062995 @default.
• W2337878444 cites W1984075943 @default.
• W2337878444 cites W1989768828 @default.
• W2337878444 cites W1992179524 @default.
• W2337878444 cites W1992692472 @default.
• W2337878444 cites W2017703699 @default.
• W2337878444 cites W2028412521 @default.
• W2337878444 cites W2034729702 @default.
• W2337878444 cites W2046913482 @default.
• W2337878444 cites W2057711031 @default.
• W2337878444 cites W2086742051 @default.
• W2337878444 cites W2093636263 @default.
• W2337878444 cites W2102638899 @default.
• W2337878444 cites W2107402669 @default.
• W2337878444 cites W2108886080 @default.
• W2337878444 cites W2109168189 @default.
• W2337878444 cites W2118544754 @default.
• W2337878444 cites W2136696335 @default.
• W2337878444 cites W2139599594 @default.
• W2337878444 cites W2144810035 @default.
• W2337878444 cites W2149685956 @default.
• W2337878444 cites W2154399948 @default.
• W2337878444 cites W2166830738 @default.
• W2337878444 cites W2166845850 @default.
• W2337878444 cites W2167461737 @default.
• W2337878444 cites W2173497140 @default.
• W2337878444 cites W2331808613 @default.
• W2337878444 cites W2341027667 @default.
• W2337878444 cites W4229949943 @default.
• W2337878444 cites W4240362928 @default.
• W2337878444 cites W4251749726 @default.
• W2337878444 cites W617702064 @default.
• W2337878444 doi "https://doi.org/10.1097/sap.0000000000000802" @default.
• W2337878444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27070671" @default.
• W2337878444 hasPublicationYear "2016" @default.
• W2337878444 type Work @default.
• W2337878444 sameAs 2337878444 @default.
• W2337878444 citedByCount "11" @default.
• W2337878444 countsByYear W23378784442018 @default.
• W2337878444 countsByYear W23378784442019 @default.
• W2337878444 countsByYear W23378784442020 @default.
• W2337878444 countsByYear W23378784442022 @default.
• W2337878444 countsByYear W23378784442023 @default.
• W2337878444 crossrefType "journal-article" @default.
• W2337878444 hasAuthorship W2337878444A5011832483 @default.
• W2337878444 hasAuthorship W2337878444A5017359925 @default.
• W2337878444 hasAuthorship W2337878444A5042267289 @default.
• W2337878444 hasAuthorship W2337878444A5056091409 @default.
• W2337878444 hasAuthorship W2337878444A5081546351 @default.
• W2337878444 hasBestOaLocation W23378784442 @default.
• W2337878444 hasConcept C126322002 @default.
• W2337878444 hasConcept C136302470 @default.
• W2337878444 hasConcept C142724271 @default.
• W2337878444 hasConcept C171089720 @default.
• W2337878444 hasConcept C198826908 @default.
• W2337878444 hasConcept C28328180 @default.
• W2337878444 hasConcept C2908647359 @default.
• W2337878444 hasConcept C502942594 @default.
• W2337878444 hasConcept C71924100 @default.
• W2337878444 hasConcept C86803240 @default.
• W2337878444 hasConcept C95444343 @default.
• W2337878444 hasConcept C99454951 @default.
• W2337878444 hasConceptScore W2337878444C126322002 @default.
• W2337878444 hasConceptScore W2337878444C136302470 @default.
• W2337878444 hasConceptScore W2337878444C142724271 @default.
• W2337878444 hasConceptScore W2337878444C171089720 @default.
• W2337878444 hasConceptScore W2337878444C198826908 @default.
• W2337878444 hasConceptScore W2337878444C28328180 @default.
• W2337878444 hasConceptScore W2337878444C2908647359 @default.
• W2337878444 hasConceptScore W2337878444C502942594 @default.
• W2337878444 hasConceptScore W2337878444C71924100 @default.
• W2337878444 hasConceptScore W2337878444C86803240 @default.
• W2337878444 hasConceptScore W2337878444C95444343 @default.
• W2337878444 hasConceptScore W2337878444C99454951 @default.
• W2337878444 hasIssue "Supplement 3" @default.
• W2337878444 hasLocation W23378784441 @default.
• W2337878444 hasLocation W23378784442 @default.
• W2337878444 hasLocation W23378784443 @default.
• W2337878444 hasOpenAccess W2337878444 @default.
• W2337878444 hasPrimaryLocation W23378784441 @default.
• W2337878444 hasRelatedWork W1965045547 @default.
• W2337878444 hasRelatedWork W1974318733 @default.
• W2337878444 hasRelatedWork W1976203623 @default.
• W2337878444 hasRelatedWork W1996688134 @default.
• W2337878444 hasRelatedWork W2178224052 @default.
• W2337878444 hasRelatedWork W2326377876 @default.
• W2337878444 hasRelatedWork W2405146356 @default.
• W2337878444 hasRelatedWork W3039644791 @default.

• next