FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2338755716> ?p ?o ?g. }

• W2338755716 endingPage "968" @default.
• W2338755716 startingPage "962" @default.
• W2338755716 abstract "Abstract To explore the etiology of congenital hypoplastic or Diamond-Blackfan anemia (DBA) we investigated in vitro erythropoiesis in nine patients. Of the nine, seven were clinically responsive to prednisone. Four were infants evaluated at the time of diagnosis. Six were never or were only minimally transfused. Those for whom prednisone had been prescribed had discontinued the drug a minimum of five months prior to study. The bone marrows of these nine patients were compared with those of hematologically normal individuals and with those of four patients with transient erythroblastopenia of childhood (TEC) whose erythroid aplasia was as severe as that of the patients with DBA. Using the plasma clot semisolid culture technique to enumerate erythroid progenitors and to evaluate the growth characteristics of the colonies to which they give rise, we concluded that at the onset of DBA: (a) erythroid progenitor frequency does not correlate with the degree of anemia and erythroblastopenia; (b) erythroid progenitor differentiation may in some cases be abnormally insensitive to crude preparations of erythropoietin; and (c) progenitor erythropoietin insensitivity in vitro does not necessarily indicate prednisone insensitivity in vivo. Thus, DBA does not appear to be solely the result of deficient formation of erythroid progenitors but is, in addition, a disorder that is due to defective progenitor differentiation in vivo." @default.
• W2338755716 created "2016-06-24" @default.
• W2338755716 creator A5024304426 @default.
• W2338755716 creator A5044759942 @default.
• W2338755716 creator A5069343341 @default.
• W2338755716 creator A5091658738 @default.
• W2338755716 date "1986-04-01" @default.
• W2338755716 modified "2023-10-16" @default.
• W2338755716 title "Defective erythroid progenitor differentiation system in congenital hypoplastic (Diamond-Blackfan) anemia" @default.
• W2338755716 cites W1517751361 @default.
• W2338755716 cites W1789486470 @default.
• W2338755716 cites W1964389322 @default.
• W2338755716 cites W1965721553 @default.
• W2338755716 cites W1966582145 @default.
• W2338755716 cites W1969686092 @default.
• W2338755716 cites W1971389590 @default.
• W2338755716 cites W1991388591 @default.
• W2338755716 cites W1994005628 @default.
• W2338755716 cites W1997173837 @default.
• W2338755716 cites W2004126780 @default.
• W2338755716 cites W2023257542 @default.
• W2338755716 cites W2028989615 @default.
• W2338755716 cites W2042684508 @default.
• W2338755716 cites W2065577646 @default.
• W2338755716 cites W2076593817 @default.
• W2338755716 cites W2091997969 @default.
• W2338755716 cites W2093900523 @default.
• W2338755716 cites W2100406695 @default.
• W2338755716 cites W2122248575 @default.
• W2338755716 cites W2282755628 @default.
• W2338755716 cites W2293879350 @default.
• W2338755716 cites W2305126270 @default.
• W2338755716 cites W2315323207 @default.
• W2338755716 cites W2332875841 @default.
• W2338755716 cites W2339964258 @default.
• W2338755716 cites W2345005943 @default.
• W2338755716 cites W2401480096 @default.
• W2338755716 cites W2412126959 @default.
• W2338755716 cites W2417706019 @default.
• W2338755716 cites W2460302150 @default.
• W2338755716 cites W2460453843 @default.
• W2338755716 cites W298649660 @default.
• W2338755716 cites W30146480 @default.
• W2338755716 cites W31973432 @default.
• W2338755716 doi "https://doi.org/10.1182/blood.v67.4.962.962" @default.
• W2338755716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3955239" @default.
• W2338755716 hasPublicationYear "1986" @default.
• W2338755716 type Work @default.
• W2338755716 sameAs 2338755716 @default.
• W2338755716 citedByCount "81" @default.
• W2338755716 countsByYear W23387557162012 @default.
• W2338755716 countsByYear W23387557162013 @default.
• W2338755716 countsByYear W23387557162014 @default.
• W2338755716 countsByYear W23387557162015 @default.
• W2338755716 countsByYear W23387557162016 @default.
• W2338755716 countsByYear W23387557162017 @default.
• W2338755716 countsByYear W23387557162018 @default.
• W2338755716 countsByYear W23387557162019 @default.
• W2338755716 countsByYear W23387557162020 @default.
• W2338755716 countsByYear W23387557162021 @default.
• W2338755716 countsByYear W23387557162022 @default.
• W2338755716 crossrefType "journal-article" @default.
• W2338755716 hasAuthorship W2338755716A5024304426 @default.
• W2338755716 hasAuthorship W2338755716A5044759942 @default.
• W2338755716 hasAuthorship W2338755716A5069343341 @default.
• W2338755716 hasAuthorship W2338755716A5091658738 @default.
• W2338755716 hasBestOaLocation W23387557161 @default.
• W2338755716 hasConcept C104317684 @default.
• W2338755716 hasConcept C126322002 @default.
• W2338755716 hasConcept C15729860 @default.
• W2338755716 hasConcept C16685009 @default.
• W2338755716 hasConcept C201750760 @default.
• W2338755716 hasConcept C203014093 @default.
• W2338755716 hasConcept C2778248108 @default.
• W2338755716 hasConcept C2778368355 @default.
• W2338755716 hasConcept C2778534260 @default.
• W2338755716 hasConcept C2778720950 @default.
• W2338755716 hasConcept C2778997081 @default.
• W2338755716 hasConcept C2779703530 @default.
• W2338755716 hasConcept C28328180 @default.
• W2338755716 hasConcept C54355233 @default.
• W2338755716 hasConcept C67705224 @default.
• W2338755716 hasConcept C71924100 @default.
• W2338755716 hasConcept C86803240 @default.
• W2338755716 hasConcept C88478588 @default.
• W2338755716 hasConceptScore W2338755716C104317684 @default.
• W2338755716 hasConceptScore W2338755716C126322002 @default.
• W2338755716 hasConceptScore W2338755716C15729860 @default.
• W2338755716 hasConceptScore W2338755716C16685009 @default.
• W2338755716 hasConceptScore W2338755716C201750760 @default.
• W2338755716 hasConceptScore W2338755716C203014093 @default.
• W2338755716 hasConceptScore W2338755716C2778248108 @default.
• W2338755716 hasConceptScore W2338755716C2778368355 @default.
• W2338755716 hasConceptScore W2338755716C2778534260 @default.
• W2338755716 hasConceptScore W2338755716C2778720950 @default.
• W2338755716 hasConceptScore W2338755716C2778997081 @default.
• W2338755716 hasConceptScore W2338755716C2779703530 @default.
• W2338755716 hasConceptScore W2338755716C28328180 @default.

• next