Matches in SemOpenAlex for { <https://semopenalex.org/work/W2338821519> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2338821519 abstract "Background:: Recent investigations get focused on characterization and isolation of natural compounds with pharmaceutical applications from terrestrial and aquatic ecosystem. Marine invertebrate natural products have been proposed due to various structural diversity. Ophiocoma eraniceus (O. erinaceus) is a brittle star species belonging to Echinodermata that distributed in Qeshm island in the Persian Gulf. Recent scientist researches have concentrated on discovery of natural resources with pharmacological and biomedical potential. Objectives:: This experiment aimed to discover phytochemical analysis and in vitro antioxidant and anti-inflammatory properties of O. erinaceus methanolic extract. Materials and Methods:: In this experimental study, the phytochemical analysis were conducted to determine saponin, phenolic and flavonoid content of brittle star and the free radical scavenging activity with two in vitro assays. In addition, the effect of methanolic brittle star extract on TGF-β expression were analysed by RT-PCR. Results:: The phytochemical studies established the presence of saponins, phenol, and flavonoids compounds in the brittle star extract and the antioxidant results from DPPH (1, 1-diphenyl-2-picrylhydrazyl), ABTS (azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) revealed that O. erinaceus displayed antioxidant activity as dose dependent manner. On the other hand, O. erinaceus extract inhibited TGF-β expression which indicate anti-inflammatory properties of O. erinaceus. Conclusions:: In conclusion, these results clearly exhibited that the O. erinaceus methanolic extract possess valuable constituents that may correspond as a natural antioxidant and anti-inflammatory agent useful in biomedicine." @default.
- W2338821519 created "2016-06-24" @default.
- W2338821519 creator A5001440552 @default.
- W2338821519 creator A5081344744 @default.
- W2338821519 date "2015-12-26" @default.
- W2338821519 modified "2023-09-26" @default.
- W2338821519 title "Phytochemical Screening, Antioxidant Effect and Down Regulation of TGF-β Induced by Ophiocoma erinaceus Brittle Star Crude Extract" @default.
- W2338821519 cites W1964801668 @default.
- W2338821519 cites W1965698145 @default.
- W2338821519 cites W1975107319 @default.
- W2338821519 cites W1975108157 @default.
- W2338821519 cites W1988581666 @default.
- W2338821519 cites W1994591665 @default.
- W2338821519 cites W1999638036 @default.
- W2338821519 cites W2001842428 @default.
- W2338821519 cites W2004212473 @default.
- W2338821519 cites W2008447537 @default.
- W2338821519 cites W2020942775 @default.
- W2338821519 cites W2042412824 @default.
- W2338821519 cites W2053393895 @default.
- W2338821519 cites W2057834213 @default.
- W2338821519 cites W2060513168 @default.
- W2338821519 cites W2066363375 @default.
- W2338821519 cites W2087902044 @default.
- W2338821519 cites W2135309905 @default.
- W2338821519 cites W2161229173 @default.
- W2338821519 cites W2162817833 @default.
- W2338821519 doi "https://doi.org/10.17795/zjrms-5194" @default.
- W2338821519 hasPublicationYear "2015" @default.
- W2338821519 type Work @default.
- W2338821519 sameAs 2338821519 @default.
- W2338821519 citedByCount "3" @default.
- W2338821519 countsByYear W23388215192020 @default.
- W2338821519 countsByYear W23388215192023 @default.
- W2338821519 crossrefType "journal-article" @default.
- W2338821519 hasAuthorship W2338821519A5001440552 @default.
- W2338821519 hasAuthorship W2338821519A5081344744 @default.
- W2338821519 hasBestOaLocation W23388215191 @default.
- W2338821519 hasConcept C104317684 @default.
- W2338821519 hasConcept C178790620 @default.
- W2338821519 hasConcept C185592680 @default.
- W2338821519 hasConcept C195475562 @default.
- W2338821519 hasConcept C206139338 @default.
- W2338821519 hasConcept C2777545159 @default.
- W2338821519 hasConcept C2778004101 @default.
- W2338821519 hasConcept C2778074487 @default.
- W2338821519 hasConcept C2778539099 @default.
- W2338821519 hasConcept C2779054382 @default.
- W2338821519 hasConcept C2781031786 @default.
- W2338821519 hasConcept C2781401929 @default.
- W2338821519 hasConcept C31903555 @default.
- W2338821519 hasConcept C55493867 @default.
- W2338821519 hasConcept C556039675 @default.
- W2338821519 hasConcept C71924100 @default.
- W2338821519 hasConceptScore W2338821519C104317684 @default.
- W2338821519 hasConceptScore W2338821519C178790620 @default.
- W2338821519 hasConceptScore W2338821519C185592680 @default.
- W2338821519 hasConceptScore W2338821519C195475562 @default.
- W2338821519 hasConceptScore W2338821519C206139338 @default.
- W2338821519 hasConceptScore W2338821519C2777545159 @default.
- W2338821519 hasConceptScore W2338821519C2778004101 @default.
- W2338821519 hasConceptScore W2338821519C2778074487 @default.
- W2338821519 hasConceptScore W2338821519C2778539099 @default.
- W2338821519 hasConceptScore W2338821519C2779054382 @default.
- W2338821519 hasConceptScore W2338821519C2781031786 @default.
- W2338821519 hasConceptScore W2338821519C2781401929 @default.
- W2338821519 hasConceptScore W2338821519C31903555 @default.
- W2338821519 hasConceptScore W2338821519C55493867 @default.
- W2338821519 hasConceptScore W2338821519C556039675 @default.
- W2338821519 hasConceptScore W2338821519C71924100 @default.
- W2338821519 hasIssue "12" @default.
- W2338821519 hasLocation W23388215191 @default.
- W2338821519 hasOpenAccess W2338821519 @default.
- W2338821519 hasPrimaryLocation W23388215191 @default.
- W2338821519 hasRelatedWork W1927350970 @default.
- W2338821519 hasRelatedWork W1993176246 @default.
- W2338821519 hasRelatedWork W2885756390 @default.
- W2338821519 hasRelatedWork W2903197222 @default.
- W2338821519 hasRelatedWork W3011356796 @default.
- W2338821519 hasRelatedWork W3028013457 @default.
- W2338821519 hasRelatedWork W4206222610 @default.
- W2338821519 hasRelatedWork W4229335346 @default.
- W2338821519 hasRelatedWork W72090376 @default.
- W2338821519 hasRelatedWork W2119847046 @default.
- W2338821519 hasVolume "17" @default.
- W2338821519 isParatext "false" @default.
- W2338821519 isRetracted "false" @default.
- W2338821519 magId "2338821519" @default.
- W2338821519 workType "article" @default.