FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2338900000> ?p ?o ?g. }

• W2338900000 endingPage "e0139375" @default.
• W2338900000 startingPage "e0139375" @default.
• W2338900000 abstract "Background Main impact of Schmallenberg virus (SBV) on livestock consists in reproductive disorders, with teratogenic effects, abortions and stillbirths. SBV pathogenesis and viral placental crossing remain currently poorly understood. Therefore, we implemented an experimental infection of ewes, inoculated with SBV at 45 or 60 days of gestation (dg). Methodology “Mourerous” breed ewes were randomly separated in three groups: eight and nine ewes were subcutaneously inoculated with 1 ml of SBV infectious serum at 45 and 60 dg, respectively (G45 and G60). Six other ewes were inoculated subcutaneously with sterile phosphate buffer saline as control group. All SBV inoculated ewes showed RNAemia consistent with previously published studies, they seroconverted and no clinical sign was reported. Lambs were born at term via caesarian-section, and right after birth they were blood sampled and clinically examined. Then both lambs and ewes were euthanatized and necropsied. Principal Findings/Significance No lambs showed any malformation suggestive of SBV infection and none of them had RNAemia or anti-SBV antibodies prior to colostrum uptake. Positive SBV RNA detection in organs was rare in both G45 and G60 lambs (2/11 and 1/10, respectively). Nevertheless most of the lambs in G45 (9/11) and G60 (9/10) had at least one extraembryonic structure SBV positive by RTqPCR. The number of positive extraembryonic structures was significantly higher in G60 lambs. Time of inoculation (45 or 60 dg) had no impact on the placental colonization success rate but affected the frequency of detecting the virus in the offspring extraembryonic structures by the time of lambing. SBV readily colonized the placenta when ewes were infected at 45 or 60 dg but infection of the fetuses was limited and did not lead to congenital malformations." @default.
• W2338900000 created "2016-06-24" @default.
• W2338900000 creator A5042434598 @default.
• W2338900000 creator A5048564209 @default.
• W2338900000 creator A5059141841 @default.
• W2338900000 creator A5062815961 @default.
• W2338900000 creator A5076143859 @default.
• W2338900000 creator A5082784374 @default.
• W2338900000 date "2015-09-29" @default.
• W2338900000 modified "2023-09-23" @default.
• W2338900000 title "Experimental Infection of Sheep at 45 and 60 Days of Gestation with Schmallenberg Virus Readily Led to Placental Colonization without Causing Congenital Malformations" @default.
• W2338900000 cites W1421504552 @default.
• W2338900000 cites W1797251532 @default.
• W2338900000 cites W1842829238 @default.
• W2338900000 cites W1967041605 @default.
• W2338900000 cites W1969218644 @default.
• W2338900000 cites W1969488249 @default.
• W2338900000 cites W1971118980 @default.
• W2338900000 cites W1979562687 @default.
• W2338900000 cites W1981915442 @default.
• W2338900000 cites W1987086317 @default.
• W2338900000 cites W1994703561 @default.
• W2338900000 cites W1998576642 @default.
• W2338900000 cites W20015979 @default.
• W2338900000 cites W2003918274 @default.
• W2338900000 cites W2011802185 @default.
• W2338900000 cites W2020524132 @default.
• W2338900000 cites W2022567100 @default.
• W2338900000 cites W2024419872 @default.
• W2338900000 cites W2025260755 @default.
• W2338900000 cites W2031249009 @default.
• W2338900000 cites W2047142803 @default.
• W2338900000 cites W2050786488 @default.
• W2338900000 cites W2053165219 @default.
• W2338900000 cites W2065955341 @default.
• W2338900000 cites W2066578441 @default.
• W2338900000 cites W2073611168 @default.
• W2338900000 cites W2078954942 @default.
• W2338900000 cites W2082610369 @default.
• W2338900000 cites W2085441330 @default.
• W2338900000 cites W2086067253 @default.
• W2338900000 cites W2090427940 @default.
• W2338900000 cites W2092178923 @default.
• W2338900000 cites W2092679691 @default.
• W2338900000 cites W2098659695 @default.
• W2338900000 cites W2112910721 @default.
• W2338900000 cites W2122422137 @default.
• W2338900000 cites W2136279222 @default.
• W2338900000 cites W2144340783 @default.
• W2338900000 cites W2145598084 @default.
• W2338900000 cites W2156414085 @default.
• W2338900000 cites W2161777943 @default.
• W2338900000 cites W2168452687 @default.
• W2338900000 cites W2488097258 @default.
• W2338900000 cites W4244606672 @default.
• W2338900000 cites W52741950 @default.
• W2338900000 doi "https://doi.org/10.1371/journal.pone.0139375" @default.
• W2338900000 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4587791" @default.
• W2338900000 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26418420" @default.
• W2338900000 hasPublicationYear "2015" @default.
• W2338900000 type Work @default.
• W2338900000 sameAs 2338900000 @default.
• W2338900000 citedByCount "21" @default.
• W2338900000 countsByYear W23389000002015 @default.
• W2338900000 countsByYear W23389000002016 @default.
• W2338900000 countsByYear W23389000002017 @default.
• W2338900000 countsByYear W23389000002018 @default.
• W2338900000 countsByYear W23389000002019 @default.
• W2338900000 countsByYear W23389000002020 @default.
• W2338900000 countsByYear W23389000002021 @default.
• W2338900000 crossrefType "journal-article" @default.
• W2338900000 hasAuthorship W2338900000A5042434598 @default.
• W2338900000 hasAuthorship W2338900000A5048564209 @default.
• W2338900000 hasAuthorship W2338900000A5059141841 @default.
• W2338900000 hasAuthorship W2338900000A5062815961 @default.
• W2338900000 hasAuthorship W2338900000A5076143859 @default.
• W2338900000 hasAuthorship W2338900000A5082784374 @default.
• W2338900000 hasBestOaLocation W23389000001 @default.
• W2338900000 hasConcept C112672928 @default.
• W2338900000 hasConcept C140793950 @default.
• W2338900000 hasConcept C159047783 @default.
• W2338900000 hasConcept C159654299 @default.
• W2338900000 hasConcept C16685009 @default.
• W2338900000 hasConcept C172680121 @default.
• W2338900000 hasConcept C203014093 @default.
• W2338900000 hasConcept C2522874641 @default.
• W2338900000 hasConcept C2776482104 @default.
• W2338900000 hasConcept C2778706330 @default.
• W2338900000 hasConcept C2779073587 @default.
• W2338900000 hasConcept C2779234561 @default.
• W2338900000 hasConcept C42407357 @default.
• W2338900000 hasConcept C46973012 @default.
• W2338900000 hasConcept C54355233 @default.
• W2338900000 hasConcept C71924100 @default.
• W2338900000 hasConcept C86803240 @default.
• W2338900000 hasConceptScore W2338900000C112672928 @default.
• W2338900000 hasConceptScore W2338900000C140793950 @default.
• W2338900000 hasConceptScore W2338900000C159047783 @default.

• next