Matches in SemOpenAlex for { <https://semopenalex.org/work/W2339349968> ?p ?o ?g. }
- W2339349968 endingPage "563" @default.
- W2339349968 startingPage "555" @default.
- W2339349968 abstract "Abstract Background In ulcerative colitis ( UC ), dietary supplements may have anti‐inflammatory properties and improve disease course. We investigated the effects of casein glycomacropeptide ( CGMP ), a fraction of bovine whey protein, in active UC . Materials and methods In a randomized open‐label intervention study, 24 patients with active UC involving 10–40 cm of the distal colon were randomized in a 2 : 1 ratio into two groups. The first group was administered their usual treatment plus a daily supplement of CGMP 30 g, and the second group was administered a dose escalation to 4800 mg oral mesalamine daily (standard treatment) for 4 weeks. Clinical, endoscopic, mucosal and circulating disease activity markers were monitored. Acceptance of and adherence to CGMP up to 8 weeks were documented. Results After 4 weeks of treatment, 10 of 16 (63%) patients who received CGMP had an unchanged or decreased Simple Clinical Colitis Activity Index ( SCCAI ), which was similar to the four of eight (50%) ( P = 0·67) patients on the standard treatment. The number of patients in which SCCAI decreased by three or more did not differ between the two groups: nine of 16 (56%) in the CGMP group vs. four of eight (50%) in the standard treatment group ( P = 0·77). Changes in disease extent and severity were similar between the two groups. CGMP was well tolerated and accepted by the patients. Conclusions The addition of CGMP as a nutritional therapy to standard treatment was safe and accepted by patients with active distal UC . The disease‐modifying effect of CGMP was similar to that of the mesalamine dose escalation." @default.
- W2339349968 created "2016-06-24" @default.
- W2339349968 creator A5016277621 @default.
- W2339349968 creator A5016284801 @default.
- W2339349968 creator A5030434452 @default.
- W2339349968 creator A5041140796 @default.
- W2339349968 creator A5045782833 @default.
- W2339349968 creator A5047102264 @default.
- W2339349968 creator A5073497390 @default.
- W2339349968 date "2016-05-14" @default.
- W2339349968 modified "2023-10-17" @default.
- W2339349968 title "Casein glycomacropeptide for active distal ulcerative colitis: a randomized pilot study" @default.
- W2339349968 cites W1859276030 @default.
- W2339349968 cites W1938907407 @default.
- W2339349968 cites W1964990230 @default.
- W2339349968 cites W1971265990 @default.
- W2339349968 cites W1979948289 @default.
- W2339349968 cites W1990435598 @default.
- W2339349968 cites W1997405434 @default.
- W2339349968 cites W1999275712 @default.
- W2339349968 cites W2001617694 @default.
- W2339349968 cites W2027268846 @default.
- W2339349968 cites W2028132552 @default.
- W2339349968 cites W2029226651 @default.
- W2339349968 cites W2031193040 @default.
- W2339349968 cites W2036494355 @default.
- W2339349968 cites W2054714660 @default.
- W2339349968 cites W2060152674 @default.
- W2339349968 cites W2060877129 @default.
- W2339349968 cites W2069386778 @default.
- W2339349968 cites W2076364921 @default.
- W2339349968 cites W2100229363 @default.
- W2339349968 cites W2102547347 @default.
- W2339349968 cites W2108332624 @default.
- W2339349968 cites W2112273094 @default.
- W2339349968 cites W2112827781 @default.
- W2339349968 cites W2115384824 @default.
- W2339349968 cites W2118794829 @default.
- W2339349968 cites W2125936939 @default.
- W2339349968 cites W2130053891 @default.
- W2339349968 cites W2142626121 @default.
- W2339349968 cites W2144353549 @default.
- W2339349968 cites W2150881345 @default.
- W2339349968 cites W2153752812 @default.
- W2339349968 cites W2159610529 @default.
- W2339349968 cites W2170219620 @default.
- W2339349968 cites W2171336112 @default.
- W2339349968 cites W2321624725 @default.
- W2339349968 cites W4210972027 @default.
- W2339349968 cites W4244626580 @default.
- W2339349968 doi "https://doi.org/10.1111/eci.12634" @default.
- W2339349968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27090817" @default.
- W2339349968 hasPublicationYear "2016" @default.
- W2339349968 type Work @default.
- W2339349968 sameAs 2339349968 @default.
- W2339349968 citedByCount "25" @default.
- W2339349968 countsByYear W23393499682017 @default.
- W2339349968 countsByYear W23393499682018 @default.
- W2339349968 countsByYear W23393499682019 @default.
- W2339349968 countsByYear W23393499682020 @default.
- W2339349968 countsByYear W23393499682023 @default.
- W2339349968 crossrefType "journal-article" @default.
- W2339349968 hasAuthorship W2339349968A5016277621 @default.
- W2339349968 hasAuthorship W2339349968A5016284801 @default.
- W2339349968 hasAuthorship W2339349968A5030434452 @default.
- W2339349968 hasAuthorship W2339349968A5041140796 @default.
- W2339349968 hasAuthorship W2339349968A5045782833 @default.
- W2339349968 hasAuthorship W2339349968A5047102264 @default.
- W2339349968 hasAuthorship W2339349968A5073497390 @default.
- W2339349968 hasConcept C126322002 @default.
- W2339349968 hasConcept C168563851 @default.
- W2339349968 hasConcept C178790620 @default.
- W2339349968 hasConcept C185592680 @default.
- W2339349968 hasConcept C2776142715 @default.
- W2339349968 hasConcept C2779134260 @default.
- W2339349968 hasConcept C2780479503 @default.
- W2339349968 hasConcept C535046627 @default.
- W2339349968 hasConcept C71924100 @default.
- W2339349968 hasConcept C90924648 @default.
- W2339349968 hasConceptScore W2339349968C126322002 @default.
- W2339349968 hasConceptScore W2339349968C168563851 @default.
- W2339349968 hasConceptScore W2339349968C178790620 @default.
- W2339349968 hasConceptScore W2339349968C185592680 @default.
- W2339349968 hasConceptScore W2339349968C2776142715 @default.
- W2339349968 hasConceptScore W2339349968C2779134260 @default.
- W2339349968 hasConceptScore W2339349968C2780479503 @default.
- W2339349968 hasConceptScore W2339349968C535046627 @default.
- W2339349968 hasConceptScore W2339349968C71924100 @default.
- W2339349968 hasConceptScore W2339349968C90924648 @default.
- W2339349968 hasIssue "6" @default.
- W2339349968 hasLocation W23393499681 @default.
- W2339349968 hasLocation W23393499682 @default.
- W2339349968 hasOpenAccess W2339349968 @default.
- W2339349968 hasPrimaryLocation W23393499681 @default.
- W2339349968 hasRelatedWork W2363553858 @default.
- W2339349968 hasRelatedWork W2369056725 @default.
- W2339349968 hasRelatedWork W2378399001 @default.
- W2339349968 hasRelatedWork W2381376498 @default.