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• W2339464862 abstract "Abstract Children with attention deficit/hyperactivity disorder (ADHD) have impaired focus on goal-relevant signals and fail to suppress goal-irrelevant distractions. To address both these issues, we developed a novel neuroplasticity-based training program that adaptively trains the resolution of challenging sensory signals and the suppression of progressively more challenging distractions. We evaluated this sensory signal-to-noise resolution training in a small sample, global mental health study in Indian children with ADHD. The children trained for 30 h over 6 months in a double-blind, randomized controlled trial. Training completers showed steady and significant improvements in ADHD-associated behaviors from baseline to post training relative to controls, and benefits sustained in a 6-month follow-up. Post-training cognitive assessments showed significant positive results for response inhibition and Stroop interference tests in training completers vs controls, while measures of sustained attention and short-term memory showed nonsignificant improvement trends. Further, training-driven improvements in distractor suppression correlated with the improved ADHD symptoms. This initial study suggests utility of signal-to-noise resolution training for children with ADHD; it emphasizes the need for further research on this intervention and substantially informs the design of a larger trial." @default.
• W2339464862 created "2016-06-24" @default.
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• W2339464862 date "2016-04-12" @default.
• W2339464862 modified "2023-10-14" @default.
• W2339464862 title "Training sensory signal-to-noise resolution in children with ADHD in a global mental health setting" @default.
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• W2339464862 doi "https://doi.org/10.1038/tp.2016.45" @default.
• W2339464862 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4872403" @default.
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