Matches in SemOpenAlex for { <https://semopenalex.org/work/W2339644604> ?p ?o ?g. }
Showing items 1 to 45 of
45
with 100 items per page.
- W2339644604 endingPage "108" @default.
- W2339644604 startingPage "99" @default.
- W2339644604 abstract "Historically, advanced renal cell cancer stood as a devastating diagnosis due to paucity of systemic therapy options. Cytokine therapy including high dose IL2 and interferon alpha comprised the mainstay of advanced renal cell cancer treatment with modest benefit. With better understanding of the biology of the Von Hippel Lindau axis in the past 2 decades, antiangiogenic therapeutics came on the scene starting late 2005 with currently 7 targeted agents approved by the FDA for the treatment of advanced renal cell cancer. Further, currently in development are check point inhibitors – a form of “targeted immunotherapy” – which have shown significant clinical efficacy in the management of this disease, marking a resurgence of immunotherapy in a more sophisticated fashion. In this review, the historical perspective, current treatment options and guilelines available and what is on the horizon in the treatment of renal cell cancer will be discussed. With advances in our understanding of this disease, treatment armamentarium has remarkably increased, thereby improving overall prognosis of patients affected with this disease." @default.
- W2339644604 created "2016-06-24" @default.
- W2339644604 creator A5020125488 @default.
- W2339644604 creator A5023616396 @default.
- W2339644604 creator A5074947350 @default.
- W2339644604 date "2016-04-07" @default.
- W2339644604 modified "2023-10-03" @default.
- W2339644604 title "Changing landscapes in the treatment of advanced renal cell carcinoma" @default.
- W2339644604 hasPublicationYear "2016" @default.
- W2339644604 type Work @default.
- W2339644604 sameAs 2339644604 @default.
- W2339644604 citedByCount "0" @default.
- W2339644604 crossrefType "journal-article" @default.
- W2339644604 hasAuthorship W2339644604A5020125488 @default.
- W2339644604 hasAuthorship W2339644604A5023616396 @default.
- W2339644604 hasAuthorship W2339644604A5074947350 @default.
- W2339644604 hasConcept C121608353 @default.
- W2339644604 hasConcept C126322002 @default.
- W2339644604 hasConcept C143998085 @default.
- W2339644604 hasConcept C177713679 @default.
- W2339644604 hasConcept C2777472916 @default.
- W2339644604 hasConcept C2777701055 @default.
- W2339644604 hasConcept C2779134260 @default.
- W2339644604 hasConcept C2781068499 @default.
- W2339644604 hasConcept C2781230642 @default.
- W2339644604 hasConcept C71924100 @default.
- W2339644604 hasConceptScore W2339644604C121608353 @default.
- W2339644604 hasConceptScore W2339644604C126322002 @default.
- W2339644604 hasConceptScore W2339644604C143998085 @default.
- W2339644604 hasConceptScore W2339644604C177713679 @default.
- W2339644604 hasConceptScore W2339644604C2777472916 @default.
- W2339644604 hasConceptScore W2339644604C2777701055 @default.
- W2339644604 hasConceptScore W2339644604C2779134260 @default.
- W2339644604 hasConceptScore W2339644604C2781068499 @default.
- W2339644604 hasConceptScore W2339644604C2781230642 @default.
- W2339644604 hasConceptScore W2339644604C71924100 @default.
- W2339644604 hasIssue "1" @default.
- W2339644604 hasOpenAccess W2339644604 @default.
- W2339644604 hasVolume "2" @default.
- W2339644604 isParatext "false" @default.
- W2339644604 isRetracted "false" @default.
- W2339644604 magId "2339644604" @default.
- W2339644604 workType "article" @default.