Matches in SemOpenAlex for { <https://semopenalex.org/work/W2339657848> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2339657848 endingPage "A343" @default.
- W2339657848 startingPage "A343.1" @default.
- W2339657848 abstract "<h3>Introduction</h3> ELAPE is associated with improved oncological outcome compared to traditional abdominoperineal excision of the rectum (APER) and has become the standard surgical technique for low rectal cancers in many centres. It is however associated with large perineal defect, encouraging some surgeons to routinely reconstruct the pelvic floor using a mesh, and may be associated with high rates of wound morbidity. The aim of study was to review the rate of perineal wound complications following ELAPE in our centre. <h3>Method</h3> All patients undergoing ELAPE for adenocarcinoma of the rectum at Leicester Royal Infirmary between January 2010 and September 2014 were identified from the prospectively maintained colorectal MDT database. Patient notes and computer records were reviewed to obtain data on the perineal closure technique and perineal wound complications, specifically wound breakdown and symptomatic perineal herniation. <h3>Results</h3> 71 patients were included in the study - 38 were male, with a median age of 71 (range 46–88) years. Eighty-nine percent underwent pre-operative long-course chemoradiotherapy. R<sub>0</sub>resection was achieved in 96%. Sixty-eight patients underwent primary perineal wound closure including omentoplasty where possible; biological mesh was used in 1 patient and 2 underwent myocutaneous flap reconstruction. Thirty-nine percent of patients developed a perineal wound complication, with 13 percent developing a deep infection associated with wound breakdown–of these 69% required surgical intervention/Vac therapy. Three patients developed a late perineal sinuses. A symptomatic perineal hernia developed in four patients (5.6%), three of whom opted for conservative management; one is currently awaiting surgical repair. <h3>Conclusion</h3> This is a large single centre series of ELAPE with good R<sub>0</sub>resection rates. ELAPE remains associated with high rates of perineal wound morbidity. We feel that the symptomatic perineal hernia rate is not high enough to justify routine use of biological mesh, and therefore a pragmatic approach to perineal reconstruction should be taken on individual patient basis, depending on tumour size and patient anatomy. <h3>Disclosure of interest</h3> None Declared." @default.
- W2339657848 created "2016-06-24" @default.
- W2339657848 creator A5010518270 @default.
- W2339657848 creator A5011984190 @default.
- W2339657848 creator A5039097526 @default.
- W2339657848 creator A5042360675 @default.
- W2339657848 creator A5063435462 @default.
- W2339657848 date "2015-06-01" @default.
- W2339657848 modified "2023-09-24" @default.
- W2339657848 title "PWE-300 Perineal wound complications in the era of extralevator abdominoperineal excision of the rectum (elape)" @default.
- W2339657848 doi "https://doi.org/10.1136/gutjnl-2015-309861.746" @default.
- W2339657848 hasPublicationYear "2015" @default.
- W2339657848 type Work @default.
- W2339657848 sameAs 2339657848 @default.
- W2339657848 citedByCount "1" @default.
- W2339657848 countsByYear W23396578482022 @default.
- W2339657848 crossrefType "journal-article" @default.
- W2339657848 hasAuthorship W2339657848A5010518270 @default.
- W2339657848 hasAuthorship W2339657848A5011984190 @default.
- W2339657848 hasAuthorship W2339657848A5039097526 @default.
- W2339657848 hasAuthorship W2339657848A5042360675 @default.
- W2339657848 hasAuthorship W2339657848A5063435462 @default.
- W2339657848 hasConcept C121608353 @default.
- W2339657848 hasConcept C126322002 @default.
- W2339657848 hasConcept C141071460 @default.
- W2339657848 hasConcept C2781074409 @default.
- W2339657848 hasConcept C2781163205 @default.
- W2339657848 hasConcept C2781171867 @default.
- W2339657848 hasConcept C2781244320 @default.
- W2339657848 hasConcept C526805850 @default.
- W2339657848 hasConcept C71924100 @default.
- W2339657848 hasConceptScore W2339657848C121608353 @default.
- W2339657848 hasConceptScore W2339657848C126322002 @default.
- W2339657848 hasConceptScore W2339657848C141071460 @default.
- W2339657848 hasConceptScore W2339657848C2781074409 @default.
- W2339657848 hasConceptScore W2339657848C2781163205 @default.
- W2339657848 hasConceptScore W2339657848C2781171867 @default.
- W2339657848 hasConceptScore W2339657848C2781244320 @default.
- W2339657848 hasConceptScore W2339657848C526805850 @default.
- W2339657848 hasConceptScore W2339657848C71924100 @default.
- W2339657848 hasIssue "Suppl 1" @default.
- W2339657848 hasLocation W23396578481 @default.
- W2339657848 hasOpenAccess W2339657848 @default.
- W2339657848 hasPrimaryLocation W23396578481 @default.
- W2339657848 hasRelatedWork W2038820439 @default.
- W2339657848 hasRelatedWork W2071486220 @default.
- W2339657848 hasRelatedWork W2125318862 @default.
- W2339657848 hasRelatedWork W2367575750 @default.
- W2339657848 hasRelatedWork W2412019314 @default.
- W2339657848 hasRelatedWork W2412025933 @default.
- W2339657848 hasRelatedWork W2412695321 @default.
- W2339657848 hasRelatedWork W2413822229 @default.
- W2339657848 hasRelatedWork W2417860966 @default.
- W2339657848 hasRelatedWork W2424755069 @default.
- W2339657848 hasRelatedWork W2521330877 @default.
- W2339657848 hasRelatedWork W2800803577 @default.
- W2339657848 hasRelatedWork W2804013870 @default.
- W2339657848 hasRelatedWork W2804989895 @default.
- W2339657848 hasRelatedWork W2906324742 @default.
- W2339657848 hasRelatedWork W2921101446 @default.
- W2339657848 hasRelatedWork W3019483951 @default.
- W2339657848 hasRelatedWork W3030333644 @default.
- W2339657848 hasRelatedWork W3038165891 @default.
- W2339657848 hasRelatedWork W3120557980 @default.
- W2339657848 hasVolume "64" @default.
- W2339657848 isParatext "false" @default.
- W2339657848 isRetracted "false" @default.
- W2339657848 magId "2339657848" @default.
- W2339657848 workType "article" @default.