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- W2339791739 abstract "The success of LDL cholesterol (LDL-C) as a predictor of atherosclerotic cardiovascular disease and a therapeutic target is indisputable. Apolipoprotein B (apoB) is a more contemporary and physiologically relevant measure of atherogenic lipoproteins. This report summarizes recent comparisons of apoB and LDL-C as biomarkers of cardiovascular risk.Multiple recent reports have found that LDL-C methods perform poorly at low concentrations (<70 mg/dl). Several meta-analyses from randomized controlled trials and large prospective observational studies have found that apoB and LDL-C provide equivalent information on risk of cardiovascular disease. More innovative analyses have asserted that apoB is a superior indicator of actual risk when apoB and LDL-C disagree.ApoB is more analytically robust and standardized biomarker than LDL-C. Large population studies have found that apoB is at worst clinically equivalent to LDL-C and likely superior when disagreement exists. Realistically, many obstacles prevent the wide spread adoption of apoB and for now providers and their patients must weigh the costs and benefits of apoB." @default.
- W2339791739 created "2016-06-24" @default.
- W2339791739 creator A5008815192 @default.
- W2339791739 creator A5075187080 @default.
- W2339791739 creator A5075435687 @default.
- W2339791739 date "2016-08-01" @default.
- W2339791739 modified "2023-09-23" @default.
- W2339791739 title "Should apolipoprotein B replace LDL cholesterol as therapeutic targets are lowered?" @default.
- W2339791739 cites W1554329500 @default.
- W2339791739 cites W1583447426 @default.
- W2339791739 cites W1594116599 @default.
- W2339791739 cites W1899603104 @default.
- W2339791739 cites W1904177816 @default.
- W2339791739 cites W1922367751 @default.
- W2339791739 cites W1967312649 @default.
- W2339791739 cites W1967742445 @default.
- W2339791739 cites W1982036768 @default.
- W2339791739 cites W1984852178 @default.
- W2339791739 cites W1984970871 @default.
- W2339791739 cites W1988034716 @default.
- W2339791739 cites W199262836 @default.
- W2339791739 cites W1992887494 @default.
- W2339791739 cites W1996258616 @default.
- W2339791739 cites W2001085422 @default.
- W2339791739 cites W2011719194 @default.
- W2339791739 cites W2015624825 @default.
- W2339791739 cites W2016678257 @default.
- W2339791739 cites W2016918979 @default.
- W2339791739 cites W2019071303 @default.
- W2339791739 cites W2030344916 @default.
- W2339791739 cites W2034831662 @default.
- W2339791739 cites W2037669982 @default.
- W2339791739 cites W2040433877 @default.
- W2339791739 cites W2041101952 @default.
- W2339791739 cites W2047213390 @default.
- W2339791739 cites W2047955620 @default.
- W2339791739 cites W2050552569 @default.
- W2339791739 cites W2052341239 @default.
- W2339791739 cites W2054299101 @default.
- W2339791739 cites W2054328698 @default.
- W2339791739 cites W2054841945 @default.
- W2339791739 cites W2059870401 @default.
- W2339791739 cites W2062834072 @default.
- W2339791739 cites W2062922797 @default.
- W2339791739 cites W2065603504 @default.
- W2339791739 cites W2073940497 @default.
- W2339791739 cites W2079102359 @default.
- W2339791739 cites W2085312558 @default.
- W2339791739 cites W2090796532 @default.
- W2339791739 cites W2101333957 @default.
- W2339791739 cites W2101864445 @default.
- W2339791739 cites W2102177480 @default.
- W2339791739 cites W2107424758 @default.
- W2339791739 cites W2107443630 @default.
- W2339791739 cites W2109095803 @default.
- W2339791739 cites W2116404316 @default.
- W2339791739 cites W2118780561 @default.
- W2339791739 cites W2123027967 @default.
- W2339791739 cites W2126397375 @default.
- W2339791739 cites W2132847836 @default.
- W2339791739 cites W2136901433 @default.
- W2339791739 cites W2143745061 @default.
- W2339791739 cites W2144684988 @default.
- W2339791739 cites W2149178462 @default.
- W2339791739 cites W2151722413 @default.
- W2339791739 cites W2152610091 @default.
- W2339791739 cites W2154836846 @default.
- W2339791739 cites W2155152595 @default.
- W2339791739 cites W2157541343 @default.
- W2339791739 cites W2160296653 @default.
- W2339791739 cites W2160452475 @default.
- W2339791739 cites W2160812379 @default.
- W2339791739 cites W2163853417 @default.
- W2339791739 cites W2164576143 @default.
- W2339791739 cites W2171921241 @default.
- W2339791739 cites W2172232070 @default.
- W2339791739 cites W2196906371 @default.
- W2339791739 cites W2207843920 @default.
- W2339791739 cites W2312580977 @default.
- W2339791739 cites W2337032743 @default.
- W2339791739 cites W3001764054 @default.
- W2339791739 cites W3031812472 @default.
- W2339791739 cites W35016999 @default.
- W2339791739 cites W4230870013 @default.
- W2339791739 cites W4234215706 @default.
- W2339791739 cites W4235564602 @default.
- W2339791739 cites W4236703259 @default.
- W2339791739 cites W4247150025 @default.
- W2339791739 cites W4255633290 @default.
- W2339791739 cites W4293084779 @default.
- W2339791739 doi "https://doi.org/10.1097/mol.0000000000000313" @default.
- W2339791739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27389631" @default.
- W2339791739 hasPublicationYear "2016" @default.
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