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- W2339810555 abstract "Inhalation of the facultative intracellular bacterium, Rhodococcus equi, can result in a severe pyogranulomatous pneumonia in young horses and immunocompromised people. This organism is able to resist innate immune defenses and establish residence within the intracellular environment of the alveolar macrophage. Virulence determinants of R. equi have yet to be fully elucidated, but all equine isolates possess a large virulence-associated plasmid and express the plasmid-encoded surface lipoprotein, VapA. Furthermore, experimental evidence has confirmed that an intact cellular immune response is necessary for clearance of the organism. Author’s address: Howard Hughes Medical Research Institute, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461. r 1997 AAEP." @default.
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- W2339810555 date "1997-01-01" @default.
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- W2339810555 title "Rhodococcus equi: Pathogenesis and Virulence" @default.
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