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- W2339843945 abstract "OBJECTIVE To understand the resistance mechanism of imipenem-resistant Acinetobacter baumannii(ABA) outbreak in intensive care unit(ICU) and make a survey of environmental contamination for making some useful measures to prevent the spread of infection and control such outbreaks.METHODS Three genes including OXA,IMP and VIM were amplified by polymerase chain reaction(PCR) and the products were sequenced by gel electrophoresis.Environmental contamination in ICU was investigated,ABA isolates were identified by API20 NE.Antibiotic susceptibility patterns were performed by disc diffusion technique.RESULTS PCR products of the appropriate size were obtained from ten isolates using primers for OXA23 gene,but no amplicons were obtained with primers targeting the IMP and VIM genes.Fifteen ABA strains and thirteen other colonized bacteria were isolated from forty environmental samples.Four ABA strains came from ventilator were indistinguishable.CONCLUSION Carrying with OXA-23 contributes to the imipenem-resistant ABA in ICU.Environmental contamination plays an important reservoir role in the outbreak.Closure of the wards,patients isolation and terminal disinfection to the wards are the fundamental measures to control such an outbreak." @default.
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- W2339843945 date "2010-01-01" @default.
- W2339843945 modified "2023-09-27" @default.
- W2339843945 title "Imipenem-resistant Acinetobacter baumannii outbreak in intensive care unit: a survey of epidemiology." @default.
- W2339843945 hasPublicationYear "2010" @default.
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