Matches in SemOpenAlex for { <https://semopenalex.org/work/W2339953088> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2339953088 abstract "Author(s): Urisman, Anatoly | Advisor(s): DeRisi, Joseph | Abstract: DNA microarray-based approaches to viral detection and discovery help overcome many limitations of the existing diagnostic methods. A panviral detection microarray has been developed in our laboratory and is comprised of oligonucleotides derived from ~1200 viral species representing all viral sequences present in the NCBI Nucleotide database as of Fall 2004. The array is capable of detecting viruses from all know viral families, including novel viruses through the use of oligonucleotides derived from the most conserved viral sequences. The platform was successfully used to discover a novel coronavirus in a viral culture sample derived from a patient with Severe Acute Respiratory Syndrome (SARS) during the 2003 outbreak. In addition, a novel retrovirus has been discovered in a subset of prostate tumors from patients with a mutation in the RNASEL gene. The platform has also been applied to clinical diagnostics for detecting viruses associated with acute respiratory infections in pediatric patients. The success of the platform has been linked to the development of new algorithms for microarray oligonucleotide selection, tools for microarray-based species identification, optimized techniques for viral nucleic acid extraction and amplification, and novel strategies for viral sequence recovery from analyzed samples." @default.
- W2339953088 created "2016-06-24" @default.
- W2339953088 creator A5015627096 @default.
- W2339953088 date "2007-11-07" @default.
- W2339953088 modified "2023-09-27" @default.
- W2339953088 title "Viral detection and discovery using DNA microarrays" @default.
- W2339953088 hasPublicationYear "2007" @default.
- W2339953088 type Work @default.
- W2339953088 sameAs 2339953088 @default.
- W2339953088 citedByCount "0" @default.
- W2339953088 crossrefType "journal-article" @default.
- W2339953088 hasAuthorship W2339953088A5015627096 @default.
- W2339953088 hasConcept C104317684 @default.
- W2339953088 hasConcept C129312508 @default.
- W2339953088 hasConcept C150194340 @default.
- W2339953088 hasConcept C159047783 @default.
- W2339953088 hasConcept C186836561 @default.
- W2339953088 hasConcept C54355233 @default.
- W2339953088 hasConcept C70721500 @default.
- W2339953088 hasConcept C86803240 @default.
- W2339953088 hasConcept C95371953 @default.
- W2339953088 hasConceptScore W2339953088C104317684 @default.
- W2339953088 hasConceptScore W2339953088C129312508 @default.
- W2339953088 hasConceptScore W2339953088C150194340 @default.
- W2339953088 hasConceptScore W2339953088C159047783 @default.
- W2339953088 hasConceptScore W2339953088C186836561 @default.
- W2339953088 hasConceptScore W2339953088C54355233 @default.
- W2339953088 hasConceptScore W2339953088C70721500 @default.
- W2339953088 hasConceptScore W2339953088C86803240 @default.
- W2339953088 hasConceptScore W2339953088C95371953 @default.
- W2339953088 hasLocation W23399530881 @default.
- W2339953088 hasOpenAccess W2339953088 @default.
- W2339953088 hasPrimaryLocation W23399530881 @default.
- W2339953088 hasRelatedWork W2087839385 @default.
- W2339953088 hasRelatedWork W2156117787 @default.
- W2339953088 hasRelatedWork W2338021250 @default.
- W2339953088 hasRelatedWork W2395606266 @default.
- W2339953088 hasRelatedWork W2412120234 @default.
- W2339953088 hasRelatedWork W2564837112 @default.
- W2339953088 hasRelatedWork W2621055106 @default.
- W2339953088 hasRelatedWork W2805540097 @default.
- W2339953088 hasRelatedWork W2890665816 @default.
- W2339953088 hasRelatedWork W2949195841 @default.
- W2339953088 hasRelatedWork W2955453545 @default.
- W2339953088 hasRelatedWork W3020036550 @default.
- W2339953088 hasRelatedWork W3091910085 @default.
- W2339953088 hasRelatedWork W3134443673 @default.
- W2339953088 hasRelatedWork W3163423704 @default.
- W2339953088 hasRelatedWork W3166780695 @default.
- W2339953088 hasRelatedWork W3177110445 @default.
- W2339953088 hasRelatedWork W3196674905 @default.
- W2339953088 hasRelatedWork W325185826 @default.
- W2339953088 hasRelatedWork W749139523 @default.
- W2339953088 isParatext "false" @default.
- W2339953088 isRetracted "false" @default.
- W2339953088 magId "2339953088" @default.
- W2339953088 workType "article" @default.