Matches in SemOpenAlex for { <https://semopenalex.org/work/W2339961055> ?p ?o ?g. }
- W2339961055 abstract "ABSTRACT The Effect of Samul-tanggahyangbuja on Anti-Depressive Behavior and ImmunityYoon-Jeong Jang, Song-Baek Kim, Chang-Min ChoiYun-Jung Seo, Han-Baek ChoDept. of Korean Gynecology and Obstetrics, College of Korean Medicine, Won-Kwang UniversityObjectives: Samul-tang and Rhizome of Cyperus rotundus L. have been frequently used in gynecologic disease. The purpose of the present study i s to explore the behavioral and neurobiological effects of Samul-tanggahyangbuja (SGH) on ovariectomized rats and to form a basis for clinical treatment.Methods: Ovariectomized rats were repeatedly stressed for over 2 weeks. After orally medicated with SGH (200 or 400 mg/kg/day), the anxiety r esponse was tested using the Elevated Plus Maze (EPM) in rats. The serum levels of estradiol and IL-4, and immunohistochemical changes of IL-4 in the Locus coer uleus (LC) and Paraventricular Nucleus (PVN) were measured.Results:1. In the EPM, SGH 400 mg significantly increased time spent on the open arms and decreased time spent on the closed arms, compared with the control group (p<0.05). 2. SGH tended to increase numbers of crossings in the open and closed arms in the EPM. However, it did not reach statistical significance. 3. SGH significantly increased the serum levels of estradiol co mpared with the control group (p<0.05).4. SGH 400 mg significantly increased the serum levels of IL-4 compared with the control group (p<0.05).5. IL-4 immunoreactivity was reduced in the control group compa red with the normal group (p<0.05). However, SGH groups (200 and 400 mg) did not produce any significant effects on levels of IL-4 in the LC and PVN.Conclusions: These results suggest that SGH possesses the anti-depressant and immuno-modulatory effects on ovariectomized rats.Key Words: Menopausal Depression, Samul-tanggahyangbuja, Elevated Plus Maze (EPM), Estradiol, IL-4, Immunohistochemistry, Rhizome of C yperus Rotundus L., Cyperi Rhizoma" @default.
- W2339961055 created "2016-06-24" @default.
- W2339961055 creator A5005745776 @default.
- W2339961055 creator A5007120692 @default.
- W2339961055 creator A5025147151 @default.
- W2339961055 creator A5066004706 @default.
- W2339961055 creator A5086360882 @default.
- W2339961055 date "2013-11-29" @default.
- W2339961055 modified "2023-09-27" @default.
- W2339961055 title "The Effect of Samul-tanggahyangbuja on Anti-Depressive Behavior and Immunity" @default.
- W2339961055 cites W1964368905 @default.
- W2339961055 cites W1969680120 @default.
- W2339961055 cites W1970374697 @default.
- W2339961055 cites W1977444106 @default.
- W2339961055 cites W1979614696 @default.
- W2339961055 cites W1984858425 @default.
- W2339961055 cites W1985438873 @default.
- W2339961055 cites W1990694352 @default.
- W2339961055 cites W1998520631 @default.
- W2339961055 cites W2000204972 @default.
- W2339961055 cites W2004642795 @default.
- W2339961055 cites W2007185182 @default.
- W2339961055 cites W2012394286 @default.
- W2339961055 cites W2024670298 @default.
- W2339961055 cites W2029707852 @default.
- W2339961055 cites W2033936075 @default.
- W2339961055 cites W2037902391 @default.
- W2339961055 cites W2039819057 @default.
- W2339961055 cites W2040766089 @default.
- W2339961055 cites W2062408214 @default.
- W2339961055 cites W2067202337 @default.
- W2339961055 cites W2067735564 @default.
- W2339961055 cites W2068315260 @default.
- W2339961055 cites W2079714688 @default.
- W2339961055 cites W2080068045 @default.
- W2339961055 cites W2082068743 @default.
- W2339961055 cites W2091507493 @default.
- W2339961055 cites W2091991161 @default.
- W2339961055 cites W2092726363 @default.
- W2339961055 cites W2093943904 @default.
- W2339961055 cites W2106498051 @default.
- W2339961055 cites W2111890533 @default.
- W2339961055 cites W2115193180 @default.
- W2339961055 cites W2124569831 @default.
- W2339961055 cites W2126795224 @default.
- W2339961055 cites W2130055389 @default.
- W2339961055 cites W2164783136 @default.
- W2339961055 cites W2165656154 @default.
- W2339961055 cites W2168451388 @default.
- W2339961055 cites W2317145215 @default.
- W2339961055 cites W2318907828 @default.
- W2339961055 cites W2396787468 @default.
- W2339961055 doi "https://doi.org/10.15204/jkobgy.2013.26.4.014" @default.
- W2339961055 hasPublicationYear "2013" @default.
- W2339961055 type Work @default.
- W2339961055 sameAs 2339961055 @default.
- W2339961055 citedByCount "1" @default.
- W2339961055 countsByYear W23399610552013 @default.
- W2339961055 crossrefType "journal-article" @default.
- W2339961055 hasAuthorship W2339961055A5005745776 @default.
- W2339961055 hasAuthorship W2339961055A5007120692 @default.
- W2339961055 hasAuthorship W2339961055A5025147151 @default.
- W2339961055 hasAuthorship W2339961055A5066004706 @default.
- W2339961055 hasAuthorship W2339961055A5086360882 @default.
- W2339961055 hasConcept C126322002 @default.
- W2339961055 hasConcept C134018914 @default.
- W2339961055 hasConcept C204232928 @default.
- W2339961055 hasConcept C2777164284 @default.
- W2339961055 hasConcept C2778956855 @default.
- W2339961055 hasConcept C556039675 @default.
- W2339961055 hasConcept C65409693 @default.
- W2339961055 hasConcept C71924100 @default.
- W2339961055 hasConcept C8264082 @default.
- W2339961055 hasConceptScore W2339961055C126322002 @default.
- W2339961055 hasConceptScore W2339961055C134018914 @default.
- W2339961055 hasConceptScore W2339961055C204232928 @default.
- W2339961055 hasConceptScore W2339961055C2777164284 @default.
- W2339961055 hasConceptScore W2339961055C2778956855 @default.
- W2339961055 hasConceptScore W2339961055C556039675 @default.
- W2339961055 hasConceptScore W2339961055C65409693 @default.
- W2339961055 hasConceptScore W2339961055C71924100 @default.
- W2339961055 hasConceptScore W2339961055C8264082 @default.
- W2339961055 hasLocation W23399610551 @default.
- W2339961055 hasOpenAccess W2339961055 @default.
- W2339961055 hasPrimaryLocation W23399610551 @default.
- W2339961055 hasRelatedWork W1169446679 @default.
- W2339961055 hasRelatedWork W1998984318 @default.
- W2339961055 hasRelatedWork W2267386046 @default.
- W2339961055 hasRelatedWork W2355369139 @default.
- W2339961055 hasRelatedWork W2363186435 @default.
- W2339961055 hasRelatedWork W2363617884 @default.
- W2339961055 hasRelatedWork W2364394158 @default.
- W2339961055 hasRelatedWork W2365411941 @default.
- W2339961055 hasRelatedWork W2365697557 @default.
- W2339961055 hasRelatedWork W2370142191 @default.
- W2339961055 hasRelatedWork W2378721496 @default.
- W2339961055 hasRelatedWork W2379839406 @default.
- W2339961055 hasRelatedWork W2380426620 @default.
- W2339961055 hasRelatedWork W2386617959 @default.
- W2339961055 hasRelatedWork W2388021066 @default.