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- W2340033016 abstract "In 1965, [5] initiated exploratory trials of immunotherapy for chronic myeloid leukemia. Patients with leukemia under satisfactory control were immunized with cultured cells, believed to be myeloblasts, in the hope that this would prevent or delay myeloblastic transformation. There was some evidence that this line of cultured cells possessed an antigen in common with the buffy coat of patients with myeloid leukemia, but not with leukocytes from normal individuals. The goal of immunization was to induce strong delayed hypersensitivity against antigens of these cultured cells. The first trial was with irradiated cells injected i.m. This resulted in antibody production, but not delayed hypersensitivity to the target cells. Our present immunization technique was then adopted. This uses living BCG organisms as adjuvant, and i.d. vaccination." @default.
- W2340033016 created "2016-06-24" @default.
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- W2340033016 date "1974-01-01" @default.
- W2340033016 modified "2023-09-24" @default.
- W2340033016 title "Immunization with Cultured Cell-BCG Mixtures" @default.
- W2340033016 cites W1981067568 @default.
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- W2340033016 doi "https://doi.org/10.1007/978-3-642-49284-6_74" @default.
- W2340033016 hasPublicationYear "1974" @default.
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