FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2340209243> ?p ?o ?g. }

• W2340209243 endingPage "5" @default.
• W2340209243 startingPage "1" @default.
• W2340209243 abstract "Anxiety disorders are among the most prevalent psychological disorders, have significant negative impacts on quality of life and the healthcare system, and yet effective treatments remain elusive. Manipulating the endocannabinoid system has demonstrated potential for treating anxiety, although the side effects of direct manipulations of cannabinoid receptors keeps them from widespread clinical use. Disrupting the degradation enzyme fatty acid amide hydrolase (FAAH) enhances endogenous signaling and may produce similar efficacy without the side effects. The current experiments examine the effects of low (5.6mg/kg) or moderate (10.0mg/kg) doses of OL-135, a FAAH inhibitor, on the acquisition and consolidation of classical fear conditioning, a common model of trauma-induced anxiety. The acquisition of contextual, but not auditory, fear conditioning was disrupted by both doses of OL-135. Shock reactivity was not affected. Due to the additional neural circuitry required for contextual, but not auditory, fear conditioning, these data suggest that endocannabinoid signaling outside the amygdala may be critical for a subset of fearful memories." @default.
• W2340209243 created "2016-06-24" @default.
• W2340209243 creator A5023949725 @default.
• W2340209243 creator A5037574560 @default.
• W2340209243 creator A5049235255 @default.
• W2340209243 creator A5061424119 @default.
• W2340209243 creator A5062356903 @default.
• W2340209243 creator A5082883417 @default.
• W2340209243 date "2016-07-01" @default.
• W2340209243 modified "2023-10-12" @default.
• W2340209243 title "FAAH inhibitor OL-135 disrupts contextual, but not auditory, fear conditioning in rats" @default.
• W2340209243 cites W1968933287 @default.
• W2340209243 cites W1969338731 @default.
• W2340209243 cites W1978677134 @default.
• W2340209243 cites W1984506322 @default.
• W2340209243 cites W1986766287 @default.
• W2340209243 cites W1989558275 @default.
• W2340209243 cites W2003956791 @default.
• W2340209243 cites W2004981165 @default.
• W2340209243 cites W2005190428 @default.
• W2340209243 cites W2007924093 @default.
• W2340209243 cites W2008356945 @default.
• W2340209243 cites W2013190169 @default.
• W2340209243 cites W2023048273 @default.
• W2340209243 cites W2024935427 @default.
• W2340209243 cites W2031806630 @default.
• W2340209243 cites W2034331710 @default.
• W2340209243 cites W2083025616 @default.
• W2340209243 cites W2084784577 @default.
• W2340209243 cites W2095256251 @default.
• W2340209243 cites W2097747770 @default.
• W2340209243 cites W2101099418 @default.
• W2340209243 cites W2141747781 @default.
• W2340209243 cites W2159551965 @default.
• W2340209243 cites W2162244350 @default.
• W2340209243 cites W2164229784 @default.
• W2340209243 cites W2614602784 @default.
• W2340209243 doi "https://doi.org/10.1016/j.bbr.2016.04.014" @default.
• W2340209243 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4877211" @default.
• W2340209243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27083303" @default.
• W2340209243 hasPublicationYear "2016" @default.
• W2340209243 type Work @default.
• W2340209243 sameAs 2340209243 @default.
• W2340209243 citedByCount "10" @default.
• W2340209243 countsByYear W23402092432017 @default.
• W2340209243 countsByYear W23402092432019 @default.
• W2340209243 countsByYear W23402092432020 @default.
• W2340209243 countsByYear W23402092432021 @default.
• W2340209243 crossrefType "journal-article" @default.
• W2340209243 hasAuthorship W2340209243A5023949725 @default.
• W2340209243 hasAuthorship W2340209243A5037574560 @default.
• W2340209243 hasAuthorship W2340209243A5049235255 @default.
• W2340209243 hasAuthorship W2340209243A5061424119 @default.
• W2340209243 hasAuthorship W2340209243A5062356903 @default.
• W2340209243 hasAuthorship W2340209243A5082883417 @default.
• W2340209243 hasBestOaLocation W23402092432 @default.
• W2340209243 hasConcept C100798922 @default.
• W2340209243 hasConcept C105795698 @default.
• W2340209243 hasConcept C118552586 @default.
• W2340209243 hasConcept C126322002 @default.
• W2340209243 hasConcept C148001335 @default.
• W2340209243 hasConcept C15744967 @default.
• W2340209243 hasConcept C16837860 @default.
• W2340209243 hasConcept C169760540 @default.
• W2340209243 hasConcept C170493617 @default.
• W2340209243 hasConcept C2776885963 @default.
• W2340209243 hasConcept C2779144063 @default.
• W2340209243 hasConcept C2780871563 @default.
• W2340209243 hasConcept C2781144285 @default.
• W2340209243 hasConcept C33923547 @default.
• W2340209243 hasConcept C39617858 @default.
• W2340209243 hasConcept C45262634 @default.
• W2340209243 hasConcept C46721173 @default.
• W2340209243 hasConcept C558461103 @default.
• W2340209243 hasConcept C71924100 @default.
• W2340209243 hasConceptScore W2340209243C100798922 @default.
• W2340209243 hasConceptScore W2340209243C105795698 @default.
• W2340209243 hasConceptScore W2340209243C118552586 @default.
• W2340209243 hasConceptScore W2340209243C126322002 @default.
• W2340209243 hasConceptScore W2340209243C148001335 @default.
• W2340209243 hasConceptScore W2340209243C15744967 @default.
• W2340209243 hasConceptScore W2340209243C16837860 @default.
• W2340209243 hasConceptScore W2340209243C169760540 @default.
• W2340209243 hasConceptScore W2340209243C170493617 @default.
• W2340209243 hasConceptScore W2340209243C2776885963 @default.
• W2340209243 hasConceptScore W2340209243C2779144063 @default.
• W2340209243 hasConceptScore W2340209243C2780871563 @default.
• W2340209243 hasConceptScore W2340209243C2781144285 @default.
• W2340209243 hasConceptScore W2340209243C33923547 @default.
• W2340209243 hasConceptScore W2340209243C39617858 @default.
• W2340209243 hasConceptScore W2340209243C45262634 @default.
• W2340209243 hasConceptScore W2340209243C46721173 @default.
• W2340209243 hasConceptScore W2340209243C558461103 @default.
• W2340209243 hasConceptScore W2340209243C71924100 @default.
• W2340209243 hasFunder F4320332161 @default.
• W2340209243 hasLocation W23402092431 @default.
• W2340209243 hasLocation W23402092432 @default.
• W2340209243 hasLocation W23402092433 @default.

• next