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- W2340230878 abstract "Although fecal hydroxy fatty acids are known to be increased in steatorrhea, we found this increase to be inconstant in different types of steatorrhea. In eight normal subjects, hydroxy acids were undetectable in three and in no case exceeded 1.2 per cent of total fecal fatty acids. In 15 patients with steatorrhea from causes other than pancreatic insufficiency, hydroxy acid excretion per day ranged from 0.2 to 11.4 gm, representing from 5.1 to 20.9 per cent of their total fecal fat loss. In five patients with comparable steatorrhea caused by pancreatic disease, hydroxy acids were undetectable in two, were below 1 per cent of fecal fat loss in two and in the fifth amounted to 2.2 per cent of this loss. The significant difference in excretion of hydroxy acids between patients with pancreatic disease and those with other types of steatorrhea may prove diagnostically useful and suggests that only nonesterified fatty acids serve as substrate for hydroxylation by intestinal bacteria." @default.
- W2340230878 created "2016-06-24" @default.
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- W2340230878 date "1968-12-26" @default.
- W2340230878 modified "2023-09-25" @default.
- W2340230878 title "Hydroxy Acid Excretion in Steatorrhea of Pancreatic and Nonpancreatic Origin" @default.
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- W2340230878 doi "https://doi.org/10.1056/nejm196812262792604" @default.
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