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- W2340251521 abstract "The neuraminidase inhibitor produced by Streptomyces sp. No. 289 has been isolated from a culture filtrate and purified, and the properties of the purified preparation have been investigated. The inhibitor has a molecular weight of about 100, 000, being free from neuraminic acid or its analogs and consisting of 88% of sugar and 12% of protein. The sugar constituent is mainly composed of equal amounts of glucose and mannose, and the protein constituent lacks S-containing amino acids. An elementary analysis gives 37.33% C, 6.12% H and 1.29% N. The activity of the inhibitor is stable to heating at 100°C for 10min and to the actions of various proteolytic enzymes, but is weakened by periodate oxidation. These properties have proved that the inhibitor is completely different from those so far reported." @default.
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- W2340251521 date "1975-01-01" @default.
- W2340251521 modified "2023-10-18" @default.
- W2340251521 title "Viral-neuraminidase inhibitors of microbial origin. III. Isolation, purification, and physical and chemical properties of neuraminidase inhibitor No. 289." @default.
- W2340251521 cites W2101627364 @default.
- W2340251521 doi "https://doi.org/10.1271/bbb1961.39.923" @default.
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