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- W2340341260 abstract "Diabetic nephropathy is associated with increased mortality in diabetic patients and is a major cause of end stage renal disease in most countries. Diabetic nephropathy seems to occur as a result of an interaction between metabolic and hemodynamic factors .Glucose dependent pathway are activated with in diabetic kidney.These include increased oxidative stress and accumulation of advanced glycated end‐product. Hemodynamic factors are also implicated in the pathogenesis of diabetic nephropathy and include increased systemic and intraglomerular pressure and activation of various vasoactive hormone pathways including renin‐angiotensin and endothelin .The purpose of this review is to bring together the current information concerning the factors involved in the pathogenesis of diabetic nephropathy." @default.
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- W2340341260 date "2010-01-01" @default.
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- W2340341260 title "PATHOGENESIS OF DIABETIC NEPHROPATHY" @default.
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