Matches in SemOpenAlex for { <https://semopenalex.org/work/W2340386721> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2340386721 endingPage "100" @default.
- W2340386721 startingPage "95" @default.
- W2340386721 abstract "The origin of excess plasma free cholesterol known to accumulate in plasma of patients or animals given total parenteral nutrition (TPN) with lipid emulsion was investigated. Rats were infused for 8 days with a specially formulated TPN solution plus either lipid emulsion (lipid-TPN) or an equicaloric volume of 25% dextrose (dextrose-TPN). Laboratory diet-fed controls were sham operated. Lipid-TPN suppressed hepatic HMG CoA reductase (HMG CoAR) activity but elevated cholesterol 7α-hydroxylase (7α-OH) activity. HMG CoAR activity, however, was increased in adipose tissue and skeletal muscle by lipid-TPN when compared to dextrose-TPN. Plasma lecithin/cholesterol acyl transfer activity was similar among all groups. It is suggested that in lipid-TPN excess plasma free cholesterol does not arise from decreased hepatic clearance or plasma esterification but may originate from extrahepatic tissue, possibly through leaching of membrane cholesterol by mesophase phospholipid present in the lipid emulsion. The changes in hepatic HMG CoAR and 7α-OH activity imply that during lipid-TPN plasma free cholesterol is cleared by the liver and catabolized to bile acid." @default.
- W2340386721 created "2016-06-24" @default.
- W2340386721 creator A5002204071 @default.
- W2340386721 creator A5032253624 @default.
- W2340386721 date "1983-07-01" @default.
- W2340386721 modified "2023-10-18" @default.
- W2340386721 title "Cholesterol and bile acid synthesis during total parenteral nutrition with and without lipid emulsion in the rat" @default.
- W2340386721 cites W1494740029 @default.
- W2340386721 cites W1507246517 @default.
- W2340386721 cites W1588834902 @default.
- W2340386721 cites W1775749144 @default.
- W2340386721 cites W1946263363 @default.
- W2340386721 cites W1967616450 @default.
- W2340386721 cites W1981309636 @default.
- W2340386721 cites W1985778027 @default.
- W2340386721 cites W1995643417 @default.
- W2340386721 cites W1996546400 @default.
- W2340386721 cites W2014972352 @default.
- W2340386721 cites W2019910947 @default.
- W2340386721 cites W2022567777 @default.
- W2340386721 cites W2024086471 @default.
- W2340386721 cites W20309224 @default.
- W2340386721 cites W2064467377 @default.
- W2340386721 cites W2065472731 @default.
- W2340386721 cites W2065777224 @default.
- W2340386721 cites W2080805159 @default.
- W2340386721 cites W2090931860 @default.
- W2340386721 cites W2095219797 @default.
- W2340386721 cites W2097174011 @default.
- W2340386721 cites W2118313918 @default.
- W2340386721 cites W2148131794 @default.
- W2340386721 cites W2148986433 @default.
- W2340386721 cites W2149677436 @default.
- W2340386721 cites W2156799866 @default.
- W2340386721 cites W2418933934 @default.
- W2340386721 cites W4247033314 @default.
- W2340386721 doi "https://doi.org/10.1093/ajcn/38.1.95" @default.
- W2340386721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6407300" @default.
- W2340386721 hasPublicationYear "1983" @default.
- W2340386721 type Work @default.
- W2340386721 sameAs 2340386721 @default.
- W2340386721 citedByCount "22" @default.
- W2340386721 countsByYear W23403867212013 @default.
- W2340386721 crossrefType "journal-article" @default.
- W2340386721 hasAuthorship W2340386721A5002204071 @default.
- W2340386721 hasAuthorship W2340386721A5032253624 @default.
- W2340386721 hasBestOaLocation W23403867211 @default.
- W2340386721 hasConcept C104950815 @default.
- W2340386721 hasConcept C126322002 @default.
- W2340386721 hasConcept C134018914 @default.
- W2340386721 hasConcept C134651460 @default.
- W2340386721 hasConcept C181199279 @default.
- W2340386721 hasConcept C185592680 @default.
- W2340386721 hasConcept C2778163477 @default.
- W2340386721 hasConcept C2778918659 @default.
- W2340386721 hasConcept C2779564620 @default.
- W2340386721 hasConcept C41625074 @default.
- W2340386721 hasConcept C55493867 @default.
- W2340386721 hasConcept C71924100 @default.
- W2340386721 hasConcept C78722104 @default.
- W2340386721 hasConcept C86803240 @default.
- W2340386721 hasConceptScore W2340386721C104950815 @default.
- W2340386721 hasConceptScore W2340386721C126322002 @default.
- W2340386721 hasConceptScore W2340386721C134018914 @default.
- W2340386721 hasConceptScore W2340386721C134651460 @default.
- W2340386721 hasConceptScore W2340386721C181199279 @default.
- W2340386721 hasConceptScore W2340386721C185592680 @default.
- W2340386721 hasConceptScore W2340386721C2778163477 @default.
- W2340386721 hasConceptScore W2340386721C2778918659 @default.
- W2340386721 hasConceptScore W2340386721C2779564620 @default.
- W2340386721 hasConceptScore W2340386721C41625074 @default.
- W2340386721 hasConceptScore W2340386721C55493867 @default.
- W2340386721 hasConceptScore W2340386721C71924100 @default.
- W2340386721 hasConceptScore W2340386721C78722104 @default.
- W2340386721 hasConceptScore W2340386721C86803240 @default.
- W2340386721 hasIssue "1" @default.
- W2340386721 hasLocation W23403867211 @default.
- W2340386721 hasLocation W23403867212 @default.
- W2340386721 hasOpenAccess W2340386721 @default.
- W2340386721 hasPrimaryLocation W23403867211 @default.
- W2340386721 hasRelatedWork W122993446 @default.
- W2340386721 hasRelatedWork W1966834268 @default.
- W2340386721 hasRelatedWork W2035331946 @default.
- W2340386721 hasRelatedWork W2081729326 @default.
- W2340386721 hasRelatedWork W2166236611 @default.
- W2340386721 hasRelatedWork W2169245865 @default.
- W2340386721 hasRelatedWork W2338318761 @default.
- W2340386721 hasRelatedWork W2396773120 @default.
- W2340386721 hasRelatedWork W2412797501 @default.
- W2340386721 hasRelatedWork W2419267943 @default.
- W2340386721 hasVolume "38" @default.
- W2340386721 isParatext "false" @default.
- W2340386721 isRetracted "false" @default.
- W2340386721 magId "2340386721" @default.
- W2340386721 workType "article" @default.