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- W2340389901 abstract "To the Editor: A devastating complication of severe, chronic constipation is a stercoral perforation (SP), in which hard, impacted stool causes pressure necrosis of the distal colon, leading to ulceration and subsequent perforation of the intestinal wall. Although uncommon, this surgical emergency disproportionally affects older adults.1 and is associated with significant perioperative mortality.2 SP is often diagnosed intraoperatively rather than preoperatively; its apparent rarity may be the result of underrecognition.3 Risk factors and diagnostic criteria for SP have been described,4 but the burden of disease is poorly defined. A retrospective review of surgical records at a tertiary care community teaching hospital was performed to better understand this condition. The goal was to identify further risk factors and to characterize the incidence of SP. After institutional review board approval was received, all individuals undergoing emergency colon resection between January 1, 2003, and December 31, 2012, at a single institution were reviewed. Individuals with SP noted in postoperative documentation were included in the study. Individuals with no clinical SP diagnosis but with suspicious or indeterminate intraoperative findings underwent close review of intraoperative descriptive findings and pathology reports. Individuals were also included in the study if they retrospectively met Maurer's stringent criteria for perforated stercoral ulcers (round or ovoid perforation >1 cm, fecalomas (Figure 1) in colon or abdomen, pressure necrosis, or chronic inflammation).3 Those with other colonic pathology, including diverticulitis, inflammatory bowel disease, and mesenteric ischemic disease, were excluded. The charts of individuals with SP were reviewed for comorbidities, risk factors, and surgical outcomes. Between January 1, 2003, and December 31, 2012, 1,098 individuals underwent colon resection at this tertiary care community teaching hospital; after the exclusion of elective cases, 326 individuals who had undergone emergency colon resection were identified. Twelve individuals with SP were identified according to documented postoperative diagnoses. The operative and pathology reports of the remaining individuals undergoing emergency colon resection with suspicious clinical findings were evaluated. Six individuals were subsequently identified and included in the study based on published SP criteria.3 The 18 individuals with SP accounted for 5.5% of all emergency colon resections over 10 years. Women accounted for 77.8% of the study group (14/18). Mean age was 72.3. Fifteen (83.3%) had a documented recent history of constipation. Twelve (66.7%) had documentation of recent narcotic use. Five (28%) had recently undergone surgery, including several orthopedic procedures. Perforations were uniformly located in the sigmoid colon or rectum and had a mean size of 2.1 cm (1.0–4.5 cm). Seventeen individuals had free perforation into the abdomen (Figure 1). One had perforation of the rectovaginal septum, leading to a colovaginal fistula. All individuals underwent resection with ostomy formation. In-hospital mortality was 28%. SP is an uncommon, life-threatening condition often affecting older adults, who frequently have chronic constipation or fecal impaction.5 Fewer than 150 cases of SP were found in the literature, but larger case series have recently been published.1, 6, 7 and may indicate rising incidence or improved recognition. The current study identified 18 individuals with SP, who accounted for 5.5% of emergency colon resections over 10 years at a tertiary care community teaching hospital. One-third of the cases met pathological criteria without evidence of clinical recognition, which supports the assertion that the condition is more common than described. Mortality (28%) was consistent with previously published results, which range from 25% to as high as 57%.2 Previously identified SP risk factors, which were also noted in this population, include chronic constipation, female sex, older age, nursing facility residence, use of constipating medications (opiates, anticholinergics, tricyclics), and evidence of fecal impaction.1, 4, 6 Several individuals had undergone recent surgical procedures, which may be a unifying etiology by exacerbating constipation and contributing to nursing home stays and opiate use. Individuals often present urgently and require immediate operative intervention. Given the high mortality of the condition, prevention and early recognition are essential, but only 10% of individuals are diagnosed preoperatively.8 Constipation affects up to 74% of elderly nursing home residents and may be seen in individuals who also have chronic abdominal pain and an altered sensorium.9, 10 This can cloud evaluation and make early diagnosis of this acute condition difficult. As useful adjuncts to a thorough history and physical, early radiography or computed tomography may combat the unreliable nature of subjective complaints and facilitate early, accurate diagnosis and treatment. Conflict of Interest: The editor in chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this paper. Author Contributions: Gough, Donovan, Greaney: concept and design; acquisition, analysis, and interpretation of data. Grotts: analysis and interpretation of data. Gough, Greaney: Preparation of manuscript. Sponsor's Role: None." @default.
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- W2340389901 date "2016-04-01" @default.
- W2340389901 modified "2023-09-27" @default.
- W2340389901 title "Perforated Stercoral Ulcer: A 10-Year Experience" @default.
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- W2340389901 doi "https://doi.org/10.1111/jgs.14057" @default.
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