Matches in SemOpenAlex for { <https://semopenalex.org/work/W2340400503> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2340400503 endingPage "1113" @default.
- W2340400503 startingPage "1104" @default.
- W2340400503 abstract "Current strategies for prevention and treatment of pump thrombosis associated with the use of left ventricular assist devices (LVADs) are discussed.LVADs provide morbidity, mortality, and quality-of-life benefits in patients with advanced heart failure. Since continuous-flow LVADs came into wide use, there have been increased reports of pump thrombosis (clot formation in the LVAD system that can lead to pump dysfunction and clinical complications). Anticoagulation and antiplatelet therapies are important for preventing pump thrombosis, although the optimal antithrombotic regimen remains unclear. International Normalized Ratio goals should be determined according to specific device characteristics and patient risk factors. Medication therapy for pump thrombosis provides a less invasive option than surgical pump exchange or heart transplantation but is associated with high risks of bleeding events, recurrent pump thrombosis, and mortality. Decisions regarding medical versus surgical management should be based on clinical status and surgical candidacy. Management of pump thrombosis may include intensified i.v. anticoagulation, i.v. or intraventricular thrombolytics, or glycoprotein IIb/IIIa inhibitors. Optimization and close monitoring of anticoagulation and antiplatelet therapy can help reduce the risk of pump thrombosis.Intensive clinical and laboratory monitoring are important in identifying signs and symptoms of LVAD thrombosis. Medical management of LVAD thrombosis can be considered an early treatment strategy before thrombi become too large and unresponsive to pharmacotherapies, but antithrombotic medications carry a high risk of bleeding complications and should be used judiciously. More definitive treatment with pump exchange or heart transplantation in appropriate candidates may be required." @default.
- W2340400503 created "2016-06-24" @default.
- W2340400503 creator A5016664711 @default.
- W2340400503 creator A5051192397 @default.
- W2340400503 creator A5086948186 @default.
- W2340400503 date "2015-07-01" @default.
- W2340400503 modified "2023-10-10" @default.
- W2340400503 title "Medication management for left ventricular assist device thrombosis" @default.
- W2340400503 cites W1964249543 @default.
- W2340400503 cites W1970183879 @default.
- W2340400503 cites W1986382991 @default.
- W2340400503 cites W1997780004 @default.
- W2340400503 cites W2006479425 @default.
- W2340400503 cites W2007999695 @default.
- W2340400503 cites W2023233861 @default.
- W2340400503 cites W2024526575 @default.
- W2340400503 cites W2026141069 @default.
- W2340400503 cites W2029859302 @default.
- W2340400503 cites W2036553170 @default.
- W2340400503 cites W2041092771 @default.
- W2340400503 cites W2078625990 @default.
- W2340400503 cites W2103149583 @default.
- W2340400503 cites W2109269649 @default.
- W2340400503 cites W2114584771 @default.
- W2340400503 cites W2126617656 @default.
- W2340400503 cites W2127825025 @default.
- W2340400503 cites W2128326189 @default.
- W2340400503 cites W2135346750 @default.
- W2340400503 cites W2164267773 @default.
- W2340400503 cites W2165719156 @default.
- W2340400503 cites W2167180463 @default.
- W2340400503 cites W2221015914 @default.
- W2340400503 cites W2316892681 @default.
- W2340400503 cites W2333144042 @default.
- W2340400503 cites W2335258604 @default.
- W2340400503 doi "https://doi.org/10.2146/ajhp140538" @default.
- W2340400503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26092961" @default.
- W2340400503 hasPublicationYear "2015" @default.
- W2340400503 type Work @default.
- W2340400503 sameAs 2340400503 @default.
- W2340400503 citedByCount "16" @default.
- W2340400503 countsByYear W23404005032016 @default.
- W2340400503 countsByYear W23404005032017 @default.
- W2340400503 countsByYear W23404005032018 @default.
- W2340400503 countsByYear W23404005032019 @default.
- W2340400503 countsByYear W23404005032020 @default.
- W2340400503 countsByYear W23404005032022 @default.
- W2340400503 crossrefType "journal-article" @default.
- W2340400503 hasAuthorship W2340400503A5016664711 @default.
- W2340400503 hasAuthorship W2340400503A5051192397 @default.
- W2340400503 hasAuthorship W2340400503A5086948186 @default.
- W2340400503 hasConcept C126322002 @default.
- W2340400503 hasConcept C141071460 @default.
- W2340400503 hasConcept C164705383 @default.
- W2340400503 hasConcept C177713679 @default.
- W2340400503 hasConcept C2777015399 @default.
- W2340400503 hasConcept C2778198053 @default.
- W2340400503 hasConcept C2778774980 @default.
- W2340400503 hasConcept C2778849806 @default.
- W2340400503 hasConcept C2779326848 @default.
- W2340400503 hasConcept C2780868729 @default.
- W2340400503 hasConcept C2911091166 @default.
- W2340400503 hasConcept C71924100 @default.
- W2340400503 hasConceptScore W2340400503C126322002 @default.
- W2340400503 hasConceptScore W2340400503C141071460 @default.
- W2340400503 hasConceptScore W2340400503C164705383 @default.
- W2340400503 hasConceptScore W2340400503C177713679 @default.
- W2340400503 hasConceptScore W2340400503C2777015399 @default.
- W2340400503 hasConceptScore W2340400503C2778198053 @default.
- W2340400503 hasConceptScore W2340400503C2778774980 @default.
- W2340400503 hasConceptScore W2340400503C2778849806 @default.
- W2340400503 hasConceptScore W2340400503C2779326848 @default.
- W2340400503 hasConceptScore W2340400503C2780868729 @default.
- W2340400503 hasConceptScore W2340400503C2911091166 @default.
- W2340400503 hasConceptScore W2340400503C71924100 @default.
- W2340400503 hasIssue "13" @default.
- W2340400503 hasLocation W23404005031 @default.
- W2340400503 hasLocation W23404005032 @default.
- W2340400503 hasOpenAccess W2340400503 @default.
- W2340400503 hasPrimaryLocation W23404005031 @default.
- W2340400503 hasRelatedWork W1971244460 @default.
- W2340400503 hasRelatedWork W2009140999 @default.
- W2340400503 hasRelatedWork W2011418530 @default.
- W2340400503 hasRelatedWork W2130824384 @default.
- W2340400503 hasRelatedWork W2143015101 @default.
- W2340400503 hasRelatedWork W2335481781 @default.
- W2340400503 hasRelatedWork W2565632862 @default.
- W2340400503 hasRelatedWork W2774859156 @default.
- W2340400503 hasRelatedWork W2920043851 @default.
- W2340400503 hasRelatedWork W4365505301 @default.
- W2340400503 hasVolume "72" @default.
- W2340400503 isParatext "false" @default.
- W2340400503 isRetracted "false" @default.
- W2340400503 magId "2340400503" @default.
- W2340400503 workType "article" @default.