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• W2340429488 abstract "Clidemia hirta L., a tropical shrub used for traditional medicine in numerous countries, could constitute a new resource of phytochemicals for cosmetic applications. In vitro micropropagation of C. hirta was used to evaluate the influence of different culture media on plant growth, production of phytochemicals, and the antioxidant and antibacterial properties of leaf extracts. Quoirin and Lepoivre medium and Lloyd and McCown's woody plant medium gave the best results. Both production of phytochemicals (i.e., flavonoids, phenolics and saponins) and biological activities were affected by the culture medium composition with the strongest effects for plants cultivated on Quoirin and Lepoivre medium. Strong correlations were shown between the antibacterial activity and the saponin content and between the antioxidant capacity and the flavonoid content. The present study shows how mineral nutrition influences the production of secondary metabolites in C. hirta, thus modulating the biological activities of extracts with a view to their possible use in the cosmetic industry. Clidemia hirta L., un arbuste tropical utilisé en médecine traditionnelle dans de nombreux pays, pourrait constituer une ressource intéressante pour des applications cosmétiques. La micropropagation de C. hirta in vitro a été utilisée pour évaluer l'influence des milieux de culture sur la croissance des plantes ainsi que le contenu phytochimique et les activités antioxydantes et antibactériennes des extraits de leurs feuilles. Le milieu Quoirin et Lepoivre et le milieu Llyod et Mc Cown donnent les meilleurs résultats. Tant les contenus en flavonoïdes, composés phénoliques et saponines que les activités biologiques sont affectés par la composition du milieu, les meilleures valeurs étant obtenues avec le milieu Quoirin et Lepoivre. Des corrélations fortes sont observées entre activité antibactérienne et contenu en saponines, ainsi qu'entre capacité antioxydante et contenu en flavonoïdes. Cette étude montre l'influence de la nutrition minérale sur la production de métabolites secondaires chez C. hirta et son effet sur les activités des extraits qui peuvent en être dérivés pour une utilisation en cosmétique." @default.
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• W2340429488 date "2016-09-01" @default.
• W2340429488 modified "2023-10-17" @default.
• W2340429488 title "Secondary metabolite accumulation, antibacterial and antioxidant properties of in vitro propagated Clidemia hirta L. extracts are influenced by the basal culture medium" @default.
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• W2340429488 doi "https://doi.org/10.1016/j.crci.2016.03.012" @default.
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