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- W2340484502 abstract "1 OZET: Tedaviye direncli depresyonlarda yeni antipsi- kotiklerin yeri Yeterli dozda, yeterli surede, uygun antidepresan ilaclar ve- rildii halde major depresif hastalar›n yaklafl›k 1/3'u anti- depresan tedavilere cevap vermemekte ve tedaviye di- rencli kalmaktad›r. Ayr›ca intihar dufluncesine sahip dep- resyonlu hastalara verilen antidepresan ilaclar›n, etkisinin c›k›fl›na kadar gecen birkac haftal›k gecikme de onemli ve cozulememifl bir sorun olarak karfl›m›zda durmaktad›r. An- tidepresan tedavi ile ilgili bir dier onemli sorun ise, devam eden tedaviye zamanla tolerans›n geliflerek antidepresan etkinliin kaybolmas› ve hastal›¤›n depreflmesidir. Butun bu gibi sebepler, gunumuzde antidepresan tedavilere di- rencli bu gibi olgularda alternatif tedavi yaklafl›mlar›n›n ge- lifltirilmesine neden olmufltur. Guclendirme tedavileri bu alternatif yontemlerden biridir. Bu yaz›da k›saca antidepre- san tedaviye direnc ve direncli olgularda atipik antipsikotik ilaclar›n etkinlii konular› gozden gecirilecektir. ABSTRACT: The place of atypical antipsychotics in the treatment- resistant depressions A third of major depressive disorder patients do not respond to treatment and are declared treatment resistant despite being prescribed appropriate antidepressants at adequate dose for adequate duration. Also few weeks lag period between the start of antidepressants and the emergence of antidepressant effect remains as a significant and unresolved problem, as suicidality in depressed patients is a serious condition requiring urgent treatment. Another significant problem about antidepressant treatment is the development of tolerance to ongoing treatment over time resulting in relapse of depression. These and similar issues caused the development of alternative treatment approaches for treatment resistant cases. Adding other medications and augmentation are examples of these approaches. In this article we reviewed the resistance to antidepressants in depression and the effectiveness of atypical antipsychotics in treatment resistant cases." @default.
- W2340484502 created "2016-06-24" @default.
- W2340484502 creator A5071350230 @default.
- W2340484502 date "2010-01-01" @default.
- W2340484502 modified "2023-09-23" @default.
- W2340484502 title "Tedaviye Dirençli Depresyonlarda Yeni Antipsikotiklerin Yeri" @default.
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